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Readouts that define the physiological distributions of drugs in tissues are an unmet challenge and at best imprecise, but are needed in order to understand both the pharmacokinetic and pharmacodynamic properties associated with efficacy. Here we demonstrate that it is feasible to follow the in vivo transport of unlabeled drugs within specific organ and tissue compartments on a platform that appli
The key step in the reaction mechanism of multicopper oxidases (MCOs)-the cleavage of the O-O bond in O-2-has been investigated using combined quantum mechanical and molecular mechanical (QM/MM) methods. This process represents a reaction pathway from the peroxy intermediate after it accepts one electron from the nearby type-1 Cu site to the experimentally-observed native intermediate, which is th
Anthropogenic N deposition may change soil conditions in forest ecosystems as demonstrated in many studies of coniferous forests, whereas results from deciduous forests are relatively scarce. Therefore the influence of N deposition on several variables was studied in situ in 45 oak-dominated deciduous forests along a N deposition gradient in southern Sweden, where the deposition ranged from 10 to
Abstract in UndeterminedRelevant source area of pollen (RSAP) and pollen productivity for 11 key taxa characteristic of the pasture woodland landscape of the Jura Mountains, Switzerland, were estimated using pollen assemblages from moss polsters at 20 sites. To obtain robust pollen productivity estimates (PPEs), we used vegetation survey data at a fine spatial-resolution (1 x 1 m(2)) and randomize
Surface water is vital resources for terrestrial life, while the rapid development of urbanization results in diverse changes in sizes, amounts, and quality of surface water. To accurately extract surface water from remote sensing imagery is very important for water environment conservations and water resource management. In this study, a new Multi-Band Water Index (MBWI) for Landsat 8 Operational
Purpose: Sustainability is an area of increasing interest for industry and its stakeholders, and some companies now aspire to address sustainability issues (e.g. carbon emissions) at strategic and operational levels. As companies are exploring the issues, they attempt to embed sustainability in their planning and management systems. It is at this point that the domains of environmental concern and
To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel
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Sveriges Farmacevtförbund Stockholm 2011-02-21 Rapport från Studieresa i USA Anna Nörby Gennerud och Malm Schiratzki från Sveriges Farmacevtförbund besökte i januari New York och Washington DC för att få kunskap och inspiration kring hur vi kan förbättra vår medlemrekrytering och medlemskommunikation, inte minst med hjälp av sociala medier. Här följer en rapport från vår resa. Vi vill understryka
Fracture Liaison Services are the best model to prevent secondary fractures. The International Osteoporosis Foundation developed a Best Practice Framework to provide a quality benchmark. After a year of implementation, we confirmed that a single framework with set criteria is able to benchmark services across healthcare systems worldwide. Introduction Despite evidence for the clinical effectivenes
P å forumet Familjeliv vädjar en frustrerad kvinna om råd. Hur ska hon hantera sin makes poddberoende? Han går runt med hörlurar mest hela tiden: när han lagar mat, diskar, snabbrastar hunden, går ut med soporna eller ner i källaren samt när han ska sova. Eftersom ”de förbannade lurarna” är ”av en bra modell som stänger ute alla ljud utifrån” är det som att hon lever med en döv – för att påkalla h
https://www.lmc.lu.se/sites/lmc.lu.se/files/2025-05/Articles.2025-05-08T09_58_53.447148428.pdf - 2026-07-13
Affilierad forskare Kontaktinformation E-post: monika [dot] lindbekk [at] soclaw [dot] lu [dot] seOrganisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsMonika Lindbekks profil i Lunds universitets forskningsportalAndra roller Postdoc Rättssociologiska institutionenForskningsområdenRättskulturer och komparativ rättGenusBeslutsfattande i domstolarPågående forskningMonika Lindbekks for
https://www.soclaw.lu.se/monika-lindbekk - 2026-07-12
Background: Biomarkers serve as a quantitative measure of brain injury and may predict cognitive outcome after cardiac arrest. This study investigates the association and predictive accuracy of acute changes in Alzheimer disease-associated biomarkers to cognitive outcome in cardiac arrest survivors.Methods: Retrospective study of the Target Temperature Management after Out-of-Hospital cardiac arreBackground: Biomarkers serve as a quantitative measure of brain injury and may predict cognitive outcome after cardiac arrest. This study investigates the association and predictive accuracy of acute changes in Alzheimer disease-associated biomarkers to cognitive outcome in cardiac arrest survivors.Methods: Retrospective study of the Target Temperature Management after Out-of-Hospital cardiac arre
The steel industry in Sweden is responsible for 10% of the annual Swedish CO2 emissions. As a way to abate this sector, H2 Green Steel are establishing a new green steel production site in Boden. Their way of producing steel, through the EAF route and by using hydrogen-reduced DRI will reduce the CO2 emissions by over 90%. Besides iron ore, steel scrap is the most important input raw material for
FORESTRY, AIR POLLUTANTS AND MULTIPLE USE ASPECTS ON BERRY PRODUCTION OF FORESTS IN SOUTH SWEDEN by Georgios Gaitanis Lund University Master' s Programme in Environmental Sciences Honours Thesis Supervisor: Bengt Nihlgård Department of Plant Ecology Lund University Summary Various methods of forest management affect the occurrence of berry species in many different ways. It is also known that atmo
https://www.lumes.lu.se/sites/lumes.lu.se/files/gaitanis_georgios.pdf - 2026-07-13
Redan i 30-årsåldern saktar det mentala tempot ner och det är dags att börja sätta in på hjärnkontot. Med en stor kognitiv reserv är det större chans att hjärnan hittar vägar för att kompensera för åldrandet, så att vi kan hålla hjärnan i trim. En frisk hjärna är en förutsättning för ett långt liv. Demens handlar inte bara om glömska utan också om att nervceller i hjärnan förstörs och gradvis förs
https://www.medicin.lu.se/forskning/vad-forskar-du-om/bygg-upp-en-hjarnbuffert - 2026-07-12
Background: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data collected from pollution monitoring sites to predict exposures at subject locations. Land-use regression (LUR) and universal kriging (UK) have been suggested as potential prediction methods. We evalua
Many modern office buildings have highly glazed facades. Their energy efficiency and indoor climate is, however, being questioned. Therefore more and more of these buildings are being built with double skin facades, which can provide: a thermal buffer zone, energy savings, wind protection with open windows, fire protection, aesthetics, solar preheating of ventilation air, sound protection, polluta
Inferential models have long been used to determine pollutant dry deposition to ecosystems from measurements of air concentrations and as part of national and regional atmospheric chemistry and transport models, and yet models still suffer very large uncertainties. An inferential network of 55 sites throughout Europe for atmospheric reactive nitrogen (N-r) was established in 2007, providing ambien
