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Amyloid-β (Aβ) is hypothesized to facilitate the spread of tau pathology beyond the medial temporal lobe. However, there is evidence that, independently of Aβ, age-related tau pathology might be present outside of the medial temporal lobe. We therefore aimed to study age-related Aβ-independent tau deposition outside the medial temporal lobe in two large cohorts and to investigate potential downstr

Background: Hypertension is the leading risk factor for cerebral small vessel disease. We aimed to determine whether antihypertensive drug classes differentially affect microvascular function in people with small vessel disease. Methods: We did a multicentre, open-label, randomised crossover trial with blinded endpoint assessment at five specialist centres in Europe. We included participants aged

Recombinant adeno-associated viruses (AAVs) are popular in vivo gene transfer vehicles. However, vector doses needed to achieve therapeutic effect are high and some target tissues in the central nervous system remain difficult to transduce. Gene therapy trials using AAV for the treatment of neurological disorders have seldom led to demonstrated clinical efficacy. Important contributing factors are

The activated B cell (ABC-like) subtype of diffuse large B cell lymphoma (DLBCL) is characterized by chronic activation of signaling initiated by immunoglobulin m (IgM). By analyzing the DNA copy number profiles of 1000 DLBCL tumors, we identified gains of 18q21.2 as the most frequent genetic alteration in ABC-like DLBCL. Using integrative analysis of matched gene expression profiling data, we fou

Incidence of differentiated thyroid carcinoma (DTC) varies considerably between ethnic groups, with particularly high incidence rates in Pacific Islanders. Here, we conducted a genome-wide association study (GWAS) involving 1,554 cases/1,973 controls of European ancestry and 301 cases/348 controls of Oceanian ancestry from the EPITHYR consortium. Our results confirmed the association with the know

Microsoft Word - Lunds universitets sommarlista 2019 – massor av experter-2.docx Lunds universitets sommarlista 2019 – massor av experter på sommarens frågor Vissa ämnen skrivs det särskilt ofta i media om under sommaren. Här finns en lista över forskare vid Lunds universitet som kan svara på vanliga sommarfrågor och en rad andra ämnen som ofta är aktuella. Medicin, mat och hälsa Fästingsmitta och

https://www.lu.se/sites/www.lu.se/files/lunds_universitets_sommarlista_2019_-_massor_av_experter.pdf - 2026-05-15

Metabolite-related dietary patterns and the development of islet autoimmunity 1Scientific RepoRtS | (2019) 9:14819 | https://doi.org/10.1038/s41598-019-51251-4 www.nature.com/scientificreports Metabolite-related dietary patterns and the development of islet autoimmunity Randi K. Johnson 1, Lauren Vanderlinden2, Brian c. Defelice3, Katerina Kechris2, Ulla Uusitalo 4, oliver fiehn 3,5, Marci Sontag1

https://www.teddy.lu.se/sites/teddy.lu.se/files/metabolite-related_dietary_patterns_pdf.pdf - 2026-05-15

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children RESEARCH ARTICLE Open Access The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children Nicole M. Frank1* , Kristian F. Lynch2, Ulla Uusitalo2, Jimin Yang2, Maria Lönnrot3, Suvi M. Virtanen4,5,6,7, Heikki Hyöty3,8, Jill M

https://www.teddy.lu.se/sites/teddy.lu.se/files/the_relationship_between_breastfeeding_and_reported_respiratory_and_gastrointestinal_infection_rates_in_young_children_pdf.pdf - 2026-05-15

Background Hexavalent chromium (Cr(VI)) is a carcinogen. Exposure to Cr(VI) may occur in different industrial processes such as chrome plating and stainless steel welding. The aim of this study was to assess occupational exposure to Cr(VI) in Denmark. Methods This cross-sectional study included 28 workers and 8 apprentices with potential Cr(VI) exposure and 24 within company controls, all recruite

Hypoglycaemia (low plasma glucose) is a serious and potentially fatal complication of insulin-treated diabetes. In healthy individuals, hypoglycaemia triggers glucagon secretion, which restores normal plasma glucose levels by stimulation of hepatic glucose production. This counterregulatory mechanism is impaired in diabetes. Here we show in mice that therapeutic concentrations of insulin inhibit g

Permanent ponds are key landscape units that supply various ecosystem services. Notably, the export of aquatic subsidies to land via emerging insects may significantly influence terrestrial food webs. Polyunsaturated fatty acids (PUFA), which enhance consumer fitness, are among the essential exported components. The patterns and drivers of dietary exports from ponds via insects remain poorly known

BACKGROUND: Circulating adiponectin and leptin have been associated with risk of pancreatic cancer. However, the relationship between long-term exposure to these adipokines in the prediagnostic period with patient survival has not been investigated.METHODS: Adipokine levels were measured in prospectively collected samples from 472 patients with pancreatic cancer. Because of sex-specific difference

The Alzheimer’s Association and the Society of Nuclear Medicine and Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) and to develop AUC for tau PET. Methods: The workgroup identified key research questions that guided a systematic literature review on clinical amyloid/tau PET. Building on this review, t

Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk nutrients Article Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk Ulla Uusitalo 1,*,†, Carin Andren Aronsson 2,† , Xiang Liu 1, Kalle Kurppa 3,4, Jimin Yang 1, Edwin Liu 5, Jennifer Skidmore 6, Christiane Winkler 7,8,9, Marian J. Rewers 10, William A. Hagopian 6, Ji

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-12/108%2009192019_679_108_MP108_Uusitalo_Nutrients_2019.pdf - 2026-05-15

Här hittar du avhandlingar av doktorander inom SWEAH. Doktorandprojekten inom SWEAH bidrar med tvärvetenskapliga perspektiv på åldrande och hälsa. Doktorandprojekten utvecklas vid SWEAH:s partnerlärosäten över hela Sverige. 2026Samskapad implementering av proaktiva samtal inför vård och omsorg i livets sista tid på särskilt boende för äldreÅsa Mikaelsson Olsson, Karolinska InstitutetOlder adults'

https://sweah.lu.se/doktorander/avhandlingar-inom-sweah - 2026-05-13

Den svenske stemme i Danmark Bente Rosenbeck Jeg stødte på Valfrid Palmgren Munch-Petersen i 00’erne, da jeg skrev på bogen Har videnskaben køn? Kvinder i forskning, som udkom i 2014.  Jeg fandt ud af, at Valfrid Palmgren havde været ansat på Københavns Universitet - ovenikøbet på mit institut, dengang Nordisk Filologi. Hun blev faktisk den første kvindelige ansatte lektor på Frue Plads i 1916. De

https://www.cors.lu.se/valfrid-palmgren-munch-petersen - 2026-05-13

Introduction to Third-Cycle Studies at the Faculties of Humanities and Theology (HTG003F), 5 credits REQUIRED READING, 2025 1. Introducing the Humanities (24-25 September) Ekström, Anders & Sverker Sörlin. “The integrative humanities – and the third research policy regime”. Smart Policies for Societies in Transition, edited by Mats Benner, Göran Marklund & Sylvia Schwaag Serger, Cheltenham, Edward

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Utbildning/doktorand/Kursplaner_och_litteraturlistor/Required_reading_2025.pdf - 2026-05-14

Universitetslektor Kontaktinformation E-post: nicklas [dot] guldaker [at] keg [dot] lu [dot] se Telefon: +462223279 Mobil: +46 72 541 10 66Organisation Institutionen för kulturgeografi och ekonomisk geografi Besöksadress: Geocentrum I, Sölvegatan 10, Lund Hämtställe: 16 WebbplatsNicklas Guldåkers profil i Lunds universitets forskningsportalAndra roller Docent Institutionen för kulturgeografi och e

https://www.cencip.lu.se/nicklas-guldaker - 2026-05-14

Översvämningsmodellering Idag används matematiska modeller, i form av datorprogram, för att simulera konsekvenser av framtida översvämningar. Det finns en stor uppsjö av modeller med olika möjligheter och begränsningar, så hur går vi egentligen till väga för att välja modell? Översvämningar hör till de naturliga katastrofer som gör störst skada. Mellan 1998 och 2009 krävde de 216 största översväHydraulic models can be used to predict the consequences of flooding events. In this project, three hydraulic models were constructed using the software HEC-RAS, and compared through a case study on Höje river catchment. The models include (i) a 1-dimensional (1D) model, where river and floodplain flow is modeled in 1D, (ii) a coupled 1D-2D model, where river flow is modeled in 1D and floodplain f