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Din sökning på "julie" gav 5476 sökträffar

ECG Quantification of Myocardial Scar in Cardiomyopathy Patients With or Without Conduction Defects Correlation With Cardiac Magnetic Resonance and Arrhythmogenesis

Background-Myocardial scarring from infarction or nonischemic fibrosis forms arrhythmogenic substrate. The Selvester QRS score has been extensively validated for estimating myocardial infarction scar size in the absence of ECG confounders. but has not been tested to quantify scar in patients with hypertrophy, bundle branch/fascicular blocks, or nonischemic cardiomyopathy. We assessed the hypothese

Discovery of epi-enprioline as a novel drug for the treatment of vincristine resistant neuroblastoma

Neuroblastoma is a childhood solid tumour originating from undifferentiated neural progenitor cells of the sympathetic nervous system. Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. In the present study, we aimed to identify novel drugs that can inhibit the growth and survival of chemoresistant neuroblastoma. High-throughput screening identified a small molecule,

Biallelic KRT5 mutations in autosomal recessive epidermolysis bullosa simplex, including a complete human keratin 5 “knock-out”

Epidermolysis bullosa simplex (EBS) is usually inherited as an autosomal dominant disease due to monoallelic gain-of-function mutations in KRT5 or KRT14. Although autosomal recessive forms of EBS have been associated with mutations in at least 10 genes, recessive EBS due to homozygous biallelic KRT5 mutations has not been reported previously; it has been hypothesized that it would result in prenat

DBT-skills system for cognitively challenged individuals with self-harm: a Swedish pilot study

Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group

Genetic regulation of spermine oxidase activity and cancer risk : a Mendelian randomization study

Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention. Here we test causality of SMOX levels with cancer risk using a Mendelian randomization analysis. We performed a GWAS of spermidine/spermine ratio to

PcoB is a defense outer membrane protein that facilitates cellular uptake of copper

Copper (Cu) is one of the most abundant trace metals in all organisms, involved in a plethora of cellular processes. Yet elevated concentrations of the element are harmful, and interestingly prokaryotes are more sensitive for environmental Cu stress than humans. Various transport systems are present to maintain intracellular Cu homeostasis, including the prokaryotic plasmid-encoded multiprotein pc

Structure of the human ClC-1 chloride channel

ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with myotonia congenita, a disease impairing muscle relaxation. Here, we present the cryo-electron microscopy (cryo-EM) structure of human ClC-1, uncovering an architecture reminiscent of that of bovine ClC-K and CLC tran

How Do Modifiable Risk Factors Affect Alzheimer's Disease Pathology or Mitigate Its Effect on Clinical Symptom Expression?

Epidemiological studies show that modifiable risk factors account for approximately 40% of the population variability in risk of developing dementia, including sporadic Alzheimer's disease (AD). Recent findings suggest that these factors may also modify disease trajectories of people with autosomal-dominant AD. With positron emission tomography imaging, it is now possible to study the disease many

Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics

Antibody radionuclide conjugates are an emerging modality for targeted imaging and potent therapy of disseminated disease. Coupling of radionuclides to monoclonal antibodies (mAbs) is typically achieved by applying non-site-specific labelling techniques. With the ambition of reducing variability, increasing labelling efficacy and stability, several site-specific conjugation strategies have been de

News and events from 2022

News updates and events from the 2030 Graduate School. NewsDecemberReduced flow of plasticsAt Helsingborg's hospital, doctors have switched from disposable to reusable items and reduced the flow of plastics, writes Sjukhusläkaren. The Agenda 2030 PhD student Linn Boberg researches plastic articles in healthcare and is interviewed in the article.Tog bort onödiga verktyg - minskade plastflödet i ope

https://www.agenda2030graduateschool.lu.se/activities/news-2025/news-and-events-2022 - 2026-04-21

Deltagarlista doktorspromotionen 2016

Jubeldoktorer Kjell Ove Nilsson Hedersdoktor Joel Robbins Marilynne Robinson Doktorer efter avlagda prov Sara Gehlin Johan Herbertsson Hedersdoktorer Catherine Barnard Kirsten Sandberg Doktorer efter avlagda prov Britta Sjöstedt Jubeldoktorer Åke Ahlberg (absens) Arne Brun Torsten Denneberg (absens) Berndt Ehinger Viking Falk (absens) Bengt Johansson Bertil Linder (absens) Thorvald Löfkvist Per Oh

https://www.lu.se/sites/www.lu.se/files/deltagarlista_doktorspromotionen_2016.pdf - 2026-04-22

Pressmeddelande-arets-framtidsbyggare-2018-181115

Pressmeddelande 2018-11-15 De blir Årets Framtidsbyggare 2018: Stort hållbarhetspris till Skanska Sverige och Malmö stad Långsiktigt arbete med energieffektivisering och hållbart byggande – det är bakgrunden till att Skanska Sverige och Malmö stad utses till Årets Framtidsbyggare 2018. Priset delas ut av Stiftelsen för utveckling av energieffektivt byggande i samarbete med Lunds universitet. För a

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/pressmeddelande-arets-framtidsbyggare-2018-181115.pdf - 2026-04-22

Blankett doktorandsamtal avstamning forvantning

Diskussionsunderlag vid antagande av ny doktorand Diskussionsunderlag för introduktion av nyantagen doktorand Namn:................................................ Syftet med detta underlag är att identifiera områden där doktorandens och handledarens förväntningar inför doktorandstudierna skiljer sig åt. Det består av en enkät som fylls i enskilt av både doktorand och handledare, och med den speci

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/blankett_doktorandsamtal_avstamning_forvantning.pdf - 2026-04-22

Nyhetsbrev fran vicerektor 12 april 2016

Microsoft Word - nyhetsbrev från vicerektor 12 april 2016.docx Nyhetsbrev  från  vicerektor  april  2016:     Strategisk  plan.  Arbetet  med  den  strategiska  planen  går  framåt  och  nu  föreligger  ett  förslag  som  ska   diskuteras  med  universitetsstyrelsen  och  i  en  grupp  av  särskilt  inbjudna  så  kallade  kritiska  vänner.   Dessa  är  representanter  från  andra  universitet  och

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/nyhetsbrev_fran_vicerektor_12_april_2016.pdf - 2026-04-22

Vår forskning i media

Psykologi är ett ämne som engagerar och forskning från institutionen förekommer flitigt i media. I dragspelsmenyn nedan kan du ta del av ett urval av tillfällen där vår forskning och våra forskare förekommit i media det senaste året. 2026 Personlighetsdraget har stark koppling till ondska, Aftonbladet, aprilSwaggap,  cirka 38 min in i avsnittet. Talkshow i P1, 7 aprilDärför söker sig inte femmor t

https://www.psy.lu.se/forskning/var-forskning-i-media - 2026-04-21

Är det fortfarande rea? – En studie kring teorierna om börsintroduktioners avvikande avkastning

Title Still on sale? – A study on the theories about the abnormal return of IPO:s Seminar date: 12/1 2017 Course: FEKH89, Corporate Finance Degree Project, Undergraduate level, Business Administration, 15 ECTS Authors: Julia Borrebaeck, Viktor Lloyd, Jesper Vamborg, Advisor/s: Tore Eriksson Key words: IPO:s, Nasdaq OMX Stockholm, underpricing, long term underperformance, comparative research Purpo