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During the period of June 2011 until July 2013, the thorax surgeon Paolo Macchiarini carried out four transplants with synthetic trachea on three different patients at the Karolinska University Hospital. These transplants entailed the later death of all the patients. Macchiarini was notified suspicion of a crime in June 2016, causing another's death, gross felony, alternatively, causing bodily
The Market Abuse Regulation (MAR) came into force on 3 July 2016 and replaced the previous Market Abuse Directive (MAD). Among the obligations regulated by MAR, there is a duty for the issuer to publish inside information. According to article 17 (1) MAR, the issuer is obligated to inform the public concerning inside information directly affecting the issuer as soon as possible. The issuer must al
On 8 July 2019, ICC Trial Chamber VI found Congolese commander Bosco Ntaganda guilty for rape as a crime against humanity. In March 2021, the appealed verdict was upheld by the Appeals Chamber of the ICC, making it the first conviction in history to sentence someone as individually criminally responsible for rape as a crime against humanity. Sexual violence in armed conflicts has been a highly to
År 2008 brakade den finansiella marknaden samman och följdes av en recession världen över som vi till viss del fortfarande brottas med. OTC-derivat, ett skräddarsytt bilateralt finansiellt instrument, har i finanskrisens efterdyningar beskyllts vara en av bovarna i dramat. Särskilt tros OTC-derivaten ha bidragit till en icke-transparens på marknaden som gjorde det omöjligt att både förutse och förIn 2008 the financial market collapsed and what followed was a worldwide recession which the market has yet to fully recover from. OTC-derivatives, which are tailor-made bilateral financial instruments, have in the aftermath of the collapse been accused of being one of the culprits. More specifically, OTC-derivatives are believed to have contributed to the opaque financial market that made it impo
Patients with systemic lupus erythematosus (SLE) face an approximately 30 % risk of thrombosis post-diagnosis. However, there remains significant knowledge gaps regarding causative mechanisms, and there is a lack of specific antithrombotic guidelines. This systematic review aims to examine the existing literature regarding the mechanisms contributing to thrombosis risk in SLE, focusing on five pre
Polycyclic aromatic hydrocarbons (PAHs) have endocrine disrupting properties and they cross the placental barrier, but studies on gestational exposure and child anthropometry are inconclusive. We aimed to elucidate the impact of early gestational PAH exposure on anthropometry from birth to 10 years of age in 1295 mother-child pairs from a nested sub-cohort of the MINIMat trial in Bangladesh. Sever
We have previously identified UMP-CMP kinase (CMPK1) as a prognostic marker for triple negative breast cancer (TNBC) by mass spectrometry (MS). In this study we evaluated CMPK1 association to prognosis in an independent set of samples by immunohistochemistry (IHC) and assessed biological pathways associated to its expression through gene set enrichment analysis (GSEA). A total of 461 TNBC paraffin
Retinal implant devices are becoming an increasingly realizable way to improve the vision of patients blinded by photoreceptor degeneration. As an electrode material that can improve restored visual acuity, carbon nanotubes (CNTs) excel due to their nanoscale topography, flexibility, surface chemistry, and double-layer capacitance. If vertically aligned carbon nanotubes (VACNTs) are biocompatible
Tree planting is widely advocated and applied in urban areas, with large-scale projects underway in cities globally. Numerous potential benefits are used to justify these planting campaigns. However, reports of poor tree survival raise questions about the ability of such projects to deliver on their promises over the long-term. Each potential benefit requires different supporting conditions-relati
Purpose Asthma is frequently reported in endurance athletes. The aim of the present study was to assess the long-term airway inflammatory response to endurance exercise in high-level athletes with and without asthma. Methods In a cross-sectional design, 20 asthmatic athletes (10 swimmers and 10 cross-country skiers), 19 athletes without asthma (10 swimmers and 9 cross-country skiers), and 24 healt
Chronic Obstructive Pulmonary Disease (COPD) is often caused by smoking and other stressors. This causes oxidative stress, which induces numerous changes on both the transcriptome and proteome of the cell. We aimed to examine if the endomembrane pathway, including the endoplasmic reticulum (ER), Golgi, and lysosomes, was disrupted in fibroblasts from COPD patients as opposed to healthy ever-smoker
Background:Transcriptomic profiles have shown promise as predictors of response to neoadjuvant chemotherapy in breast cancer (BC). This study aimed to explore their predictive value in the advanced BC (ABC) setting.Methods:In a Phase 3 trial of first-line chemotherapy in ABC, a fine needle aspiration biopsy (FNAB) was obtained at baseline. Intrinsic molecular subtypes and gene modules related to i
På biologifaktasidorna förekommer bilder från följande upphovspersoner. Ett stort tack till dem.Encyclopedia of LifeJ.C. SchouNobu TamuraAlex DunkelArthur ChapmanZbyszek BoratynskiDick CulbertTassilo RauMalcolm StoreN. SlothJennifer A. ClackDavid BlankMalcolm StoreyCarlos Henrique Luz Nunes de AlmeidaJerzy StrzeleckiGerald och Buff CorsiThe Darwin Initiative Centre for Bat ResearchA. NeumannLaia L
https://www.biologi.lu.se/bilder-och-videoer-pa-webbplatsen - 2026-05-17
1921 spreds ryktet över världen att det fanns en fungerande behandling vid svår barndiabetes. Desperata föräldrar till döende diabetesbarn vädjade om insulinbehandling men den kanadensiska kvartetten bakom upptäckten tvingades nästan alltid säga nej. Bristen var för stor och forskarna klarade inte av att tillverka insulin i stor skala. Bertram Collip, en av de fyra bakom upptäckten i Toronto, hade
https://www.diabetesportalen.lu.se/diabeteshistoria/efter-desperat-vantan-nar-antligen-insulinet-patienterna - 2026-05-17
FinansieringsmöjligheterStörre delen av Medicinska fakultetens doktorander studerar på deltid med en anställning inom framförallt sjukvården. Utbildningen bedrivs då delvis inom ramen för den kliniska anställningen. De doktorander som bedriver studier på heltid finansieras primärt genom en doktorandanställning vid Medicinska fakulteten. Heltidsstudier Vid heltidsstudier används primärt en doktoran
https://www.intramed.lu.se/doktorera/att-utbilda-sig-pa-forskarniva/finansiering-av-forskarutbildning - 2026-05-17
