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The European XFEL is a research facility that delivers extremely bright and short coherent X-ray pulses of tunable energy at MHz repetition rate, providing unprecedented capabilities to conduct scientific research across multiple domains. Among the suite of deployed detectors, several ePix100 modules, belonging to the family of ePix detectors developed at SLAC, are used. These charge-integrating h
Excited state dynamics of three iron(II) carbene complexes that serve as prototype Earth-abundant photosensitizers were investigated by ultrafast optical spectroscopy. Significant differences in the dynamics between the investigated complexes down to femtosecond time scales are used to characterize fundamental differences in the depopulation of triplet metal-to-ligand charge-transfer (3MLCT) excit
IMPORTANCE AND AIMS: Diabetic microvascular complications significantly impact morbidity and mortality. This review focuses on machine learning/artificial intelligence (ML/AI) in predicting diabetic retinopathy (DR), diabetic kidney disease (DKD), and diabetic neuropathy (DN).METHODS: A comprehensive PubMed search from 1990 to 2023 identified studies on ML/AI models for diabetic microvascular comp
Soil moisture (i.e., the changes in the gravimetric soil water content) redistribution is closely linked with root distribution and preferential flow in soils. This study aimed at exploring the soil water content distribution in the presence of root-enhanced preferential flow in deciduous (Quercus variabilis BI.) and coniferous forests (Platycladus orientalis (L.)).
Mental health problems often appear at a young age. As the labour market places higher demands for education and competence, mental health services are focusing on young adults’ support needs for school and career opportunities. This study is a single case of an integrated supported education and employment unit in Sweden over an 18-month period. Multiple data sources illustrate the process of sup
Aqueous dispersions of charged-neutral block copolymers (poly(acrylamide)-b-poly(acrylate)) complexed with an oppositely charged surfactant (dodecyltrimethylammonium) have been prepared by different approaches: the simple mixing of two solutions (MS approach) containing the block copolymer and surfactant, with their respective simple counterions, and dispersion of a freeze-dried complex salt prepa
Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro
Migration has a global impact, but it also intersects with local and nationalissues. In 2020, 281 million people lived outside their country of birth or citizenship, according to the United Nations Global Migration Database. The number of persons displaced across international borders is increasing due to conflict, persecution, and violence. Most of the world’s refugees and asylum seekers live i
The determination of lead in permanent teeth is a useful measure of past exposure in early childhood since these teeth are mineralized in early childhood. Particle-induced X-ray emission (PIXE) analysis has been shown to be a method with good applicability for the contamination-free analysis of elements heavier than calcium in dental hard tissues. The method is rapid and nondestructive. The purpos
Purpose – This study aims to explore how municipalities incorporate circular requirements into construction project procurement processes. The aim is to identify practical strategies that support circular implementation in construction projectsDesign/methodology/approach – Using a qualitative approach based on a case study and semi-structured interviews with Swedish public purchasers, the research
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis is shaped not only by viral entry mechanisms but also by interactions with host and microbial factors. The viral spike (S) protein can bind Gram-negative bacterial lipopolysaccharide (LPS), a driver of hyperinflammation in severe COVID-19. How viral evolution over the years alters this interaction remains unclear. Here, we i
BACKGROUND: GP recruitment and retention difficulties challenge the traditional general practice model. Task-shifting and relieving GPs from financial risk have been suggested to make primary care more attractive. In Sweden's multiprofessional team-based primary care system, GPs usually work as salaried employees and there is extensive task-shifting. Salaried employment facilitates mobility, poten
We have adapted an optical transmission microscope to multispectral imaging in order to diagnose Plasmodium falciparum without using fluorescent labels for parasites as is the case for the thick and thin blood smears. We show how a set of monochromatic Light Emitting Diodes (LEDs) has provided an efficient contrast and spatial resolution to identify the parasites inside the erythrocytes. The obtai
Background: Obstetrical anal sphincter injuries are complications of vaginal birth that have the potential to cause substantial maternal morbidity. Predicting these injuries might help to improve maternal care as well as antenatal counseling and patient education. Previous attempts to create prediction models have in many cases involved variables only known postpartum, which limits their use in an
Health-related quality of life (HRQoL) has been shown to predict overall survival (OS) in several different malignancies, but not in patients with small intestinal neuroendocrine tumours (siNET). We evaluated the influence of HRQoL on survival in patients with siNET. We included 85 patients with advanced siNET who completed the validated HRQoL instruments, EORTC QLQ-C30 and GI.NET21. We used Cox p
Background: Bioresorbable scaffolds have been associated with inferior outcomes compared to contemporary permanent metallic drug-eluting stents (DES) for percutaneous coronary intervention, particularly within the initial years after implantation; however, their long-term performance remains uncertain. This study aimed to evaluate the long-term outcomes of Swedish patients treated with Absorb bior
This article examines bordering via bureaucratic violence in Myanmar in relation to civil documentation. We categorize bureaucratic encounters into five modalities of bureaucratic violence: deferred citizenship and higher evidentiary burdens; negative discretion in administrative decision-making; denationalization; administrative erasure; and movement restrictions. Since the 2021 military coup, su
Purpose: The PET Response Criteria in Solid Tumours (PERCIST) 1.0 provides a standardized framework for evaluating treatment response using [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography – computed tomography (PET-CT), but its clinical use is hindered by manual complexity. This study presents coPERCIST, an artificial intelligence (AI)-assisted module integrated into the RECOMIA pl
