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Osteoarthritis (OA) of the knee can be defined as primary (non-traumatic) or secondary (post-traumatic). Both non-traumatic OA and post-traumatic OA have been described predominantly in the medial compartment of the knee. The objective of this study was to compare the location of structural radiographic changes in non-traumatic OA and post-traumatic OA. A non-traumatic cohort, consisting of 155 pa
Peptide hormones may occur in particularly low amounts in samples from small animals. Hence, in a rat microdialysis study conventional immunoassays were not sufficiently sensitive to measure gastrin in the dialysis samples. We therefore exploited the observation that antibodies raised against the homologous hormone cholecystokinin (CCK) occasionally bind gastrin peptides with significantly higher
Objective: To evaluate the impact of an extruded muesli product based on -glucan-rich oat bran on postprandial glycaemia and insulinaemia. Subject/Design: The study is divided in two series. Blood glucose and serum insulin responses were studied after subjects consuming test meals including a serving of muesli with 3 g (series 1) and 4 g (series 2) of -glucans, respectively. The muesli was a comp
The posttranslational modification of proteins has the potential to generate neoepitopes that may subsequently trigger immune responses. The carbamylation of lysine residues to form homocitrulline may be a key mechanism triggering inflammatory responses. We evaluated the role of carbamylation in triggering immune responses and report a new role for this process in the induction of arthritis. Immun
A resonant enhancement of the water-(1)H relaxation rate at three distinct frequencies in the range 0.5-3MHz has been observed in a variety of aqueous biological systems. These so-called quadrupole (Q) peaks have been linked to a dipolar flip-flop polarization transfer from (1)H nuclei to rapidly relaxing amide (14)N nuclei in rotationally immobilized proteins. While the Q-peak frequencies conform
Organometal halide (OMH) perovskites have attracted lots of attention over the last several years due to their very promising performance as the materials for solar cells and light-emitting devices. Photophysical processes in these hybrid organic inorganic semiconductors are still heavily debated. To know precise absorption spectra is absolutely necessary for quantitative understanding of the fund
Previous studies on the extreme thermophile Caldicellulosiruptor saccharolyticus revealed that the organism produces high yields of hydrogen on glucose and xylose, the major components of lignocellulosic hydrolysates. Preliminary experiments on mixed sugar substrates, however, indicated that xylose was preferred over glucose. The sugar preference of some other extreme thermophiles, including Caldi
Aims: To analyse, at a one year follow up, cost offset and outcomes of changing the physical activity (PA) behaviour due to a primary care intervention. Methodology: Participants were 528 inactive individuals with life-style related health problems, 18-84 years, and randomised into a high-dose intervention group (n=270) or a low-dose intervention group (n=258). The four month lasting intervention
The purpose of this study is to examine the extent to which Swiss companies engage in corporate entrepreneurship. To that end, a case study was undertaken to better understand how corporate entrepreneurship is practiced in the watch-making industry. Using a stratified sampling method, 18 corporate-level managers of Swiss watch manufacturers were interviewed over a 5-month period to determine their
The fillet of the gear tooth is highly stressed in operation; so for heavily loaded gears, the fillet geometry must be controlled. The manufacturer's task is to, within acceptable tolerances, produce the gear to the designer's specifications regardless of the manufacturing method. Most often gear cutting tools are used that work under generating conditions. The tool will form the gear tooth; so to
Context: Most previous prospective studies suggest that low serum IGF-1 associates with increased risk of cardiovascular disease (CVD) events whereas other studies suggest that high serum IGF-1 associates with increased risk of CVD events. Objective: We tested the hypothesis that not only low, but also high serum IGF-1 levels associate with increased risk of CVD events in elderly men. Setting and
We present a quantized model of a harmonically confined dot atom with inherent damping in the presence of a transverse magnetic field. The model leads to a non-Hermitian Hamiltonian in coordinate space. We have analytically studied the effects of damping on Rabi type oscillations of the system. The model explains the decoherence of Rabi oscillations in a Josephson Junction.
Structural properties and the topology of polyelectrolyte complexes (PECs) formed in solution have been investigated under different conditions by Monte Carlo simulations using a coarse-grained model. The extension of individual polyions has been characterized by their radius of gyration, whereas the composition of the complexes has been investigated by their net charge and their internal topologi
L-2,L-3-edge X-ray absorption spectroscopy (XAS) has demonstrated unique capabilities for the analysis of the electronic structure of di-Ru complexes such as the blue dimer cis,cis-[(Ru2O)-O-III(H2O)(2)(bpy)(4)](4+) water oxidation catalyst. Spectra of the blue dimer and the monomeric [Ru(NH3)(6)](3+) model complex show considerably different splitting of the Ru L-2,L-3 absorption edge, which refl
Frequent or chronic tension-type headache in children is a prevalent and debilitating condition for the child, often leading to medication overuse. To explore the relationship between physical factors and tension-type headache in children, the quality of repeated measures was examined. The aim of the present study was to determine the test-retest repeatability of parameters determining isometric n
Servicizing is a business model that holds the potential to support a shift towards more sustainable production and consumption by selling to the consumer the product's function, rather than the material product itself. This can offer direct environmental benefits by reducing the material and energy intensity of market transactions. Servicizing based business offers are starting emerging on the ma
Lymphoedema after breast cancer surgery is a chronic condition. Lymphoedema treatment consists of information/advice, compression, physical exercise, skin care, and manual lymph drainage. Little is known about how patients experience, adapt, and respond to lymphoedema treatment. Thus, the purpose of the study was to investigate and describe women's perceptions of lymphoedema treatment after breast
A dietary survey was performed during a large screening study in Sweden among 13-year-old adolescents. The aim was to study how the intake of food groups was affected by a screening-detected diagnosis of coeliac disease (CD) and its gluten-free (GF) treatment. Food intake was reported using a FFQ, and intake reported by the adolescents who were diagnosed with CD was compared with the intake of two
We present how dramatically the nonequilibrium nature of an oppsitely charged polyelectrolyte/surfactant mixture can affect the interfacial properties. We show for the first time that the cliff edge peak in the surface tension of the poly(diallydimethylammonium chloride)/sodium dodecyl surfate system is produced as a direct result of depletion of surface-active material from the bulk solution due
