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OBJECTIVES: Up to 50% of patients qualified for cardiac resynchronization therapy (CRT) have documented atrial fibrillation (AF) prior to CRT-implantation. This finding is associated with worse prognosis but few studies have evaluated the importance of post-implant device-detected AF. This study aimed to assess the prognostic impact of device-detected atrial high rate episodes (AHRE), as a surroga
IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns
A heel ulcer is considered to be a serious complication in patients with diabetes, and there is limited information regarding outcome. In most of the literature, a poor prognosis is described. The aim of this study was to investigate a large cohort of ulcers located in the heel in patients with diabetes. Seven hundred and sixty-eight patients [median age 73 (17-98)], presenting with a heel ulcer a
A comparative study of the antioxidant activity of hydroxytyrosol (HT) and phosphatidyl derivatives of hydroxytyrosol (PHT) added at increasing concentrations to diverse edible oils (lard oil, refined olive oil, and diacylglycerol-rich oil) was performed. Antioxidant activity index was estimated as the ratio of induction time in presence of the compounds to induction time in their absence, after o
The present research aims at understanding the value of travel guidebooks as an object of consumption in the context of the digital age. It does so by applying a consumer value perspective to an object that has traditionally been studied as an information channel or as a cultural text and not as an object of consumption. Holbrook’s consumer value framework was adopted to identify the value dimensi
In this paper, a new class of continuous distributions with two extra positive parameters is introduced and is called the Type II General Exponential (TIIGE) distribution. Some special models are presented. Asymptotics, explicit expressions for the ordinary and incomplete moments, moment residual life, reversed residual life, quantile and generating functions and stress-strengh reliability functio
Consistency in civil servant decisions is paramount to upholding judicial equality for citizens and individuals seeking safety through governmental intervention. We investigated refugee status decisions made by a sample of civil servants at the Swedish Migration Agency. We hypothesized, based on the emotional demands such decisions bring with them, that participants would exhibit a compassion fade
Increasing evidence links intraneuronal β-amyloid (Aβ 42) accumulation with the pathogenesis of Alzheimer's disease (AD). In Aβ precursor protein (APP) mutant transgenic mice and in human AD brain, progressive intraneuronal accumulation of Aβ42 occurs especially in multivesicular bodies (MVBs). We hypothesized that this impairs the MVB sorting pathway. We used the trafficking of the epidermal grow
To investigate the genetic identities of the mucins secreted in cystic fibrosis (CF) airways, sputum was collected from five individuals. Samples were separated into gel and sol phases by high-speed centrifugation and the gel phase was extracted in 6 M guanidinium chloride. The 'insoluble' residue remaining after extraction of the gel phase was brought into solution by reduction/alkylation. Densit
Low-density polethylene disks with smooth or course surfaces were implanted in the abdominal wall of rats, and the tissue response was evaluated after 1, 6, or 12 weeks. Cell damage was detected by two different methods. Cells with increased membrane permeability could be identified using fluorescence microscopy by injection of propidium iodide prior to the killing of the rats. Second, cell death
Objective: There is a growing view that inherited or acquired thrombophilia may predispose a woman towards an adverse pregnancy outcome. The aim of this study was to investigate whether risk factors for placental abruption because of such thrombophilias (such as carriership of factor V Leiden (FVL), prothrombin G20210A gene mutation and homozygous MTHFR C677T) might be used as a predictor for plac
In Sweden there has been a move towards more cost reflective price models for district heating in order to reduce economic risks that comes with variable heat demand and high shares of fixed assets. The keywords in the new price models are higher shares of fixed cost, seasonal energy prices and charging for capacity. Also components that are meant to serve as incentives to affect behaviour are int
Purpose: Effective engineering asset management is essential in delivering public services safely whilst avoiding breakdowns and accidents. To ensure asset safety and sustainability, public sector firms have to adopt new processes and practices. It is the role of supervisors to implement the changes, and as part of the New Public Management (NPM) public sector reforms, public sector asset managers
Background: Incidental gallbladder cancer is a rare event, and its prognosis is largely affected by the tumour stage and treatment. The aim of this study was to analyse the management, treatment and survival of patients with incidental gallbladder cancer in a national cohort over a decade. Methods: Patients were identified through the Swedish Registry of Gallstone Surgery (GallRiks). Data were cro
The physiology underlying the intracranial pressure (ICP) curve morphology is not fully understood. Recent research has suggested that the morphology could be dependent on arterial cerebral inflow and the physiological and pathophysiological properties of the intracranial cavity. If understood, the ICP curve could provide information about the patient’s cerebrovascular state important in individua
In this note, we show that the first-order logic IK! is sound with regard to the models obtained from continuum-valued Łukasiewicz-models for first-order languages by treating the quantifiers as infinitary strong disjunction/conjunction rather than infinitary weak disjunction/conjunction. Moreover, we show that these models cannot be used to provide a new consistency proof for the theory of truth
In this research a method to calibrate a river hydraulic model (HEC-RAS) using ground-based measurements of an observed flash flood is presented. Applications of the ground truth measurement of flood water depths and flooded areas within a reach of Neka River in Northern of Iran are discussed. The model is calibrated using the Manning's roughness coefficient based on 200-year flood event that took
This study examines the interdependence between research and development (R&D) resources, coopetitive performance, and extent of cooperation in development-related standardization settings that involve network effects. Coopetitive performance is measured as the firm’s influence on the change process of standards. Cooperation is measured as the number of firm technology partners in influencing
