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Popular Abstract in Swedish Det är sedan länge känt att för samma bildkvalitet kan patientstråldosen variera kraftigt mellan två olika sjukhus för en och samma röntgenundersökning. Det finns ett stort utrymme för sänkning av patientstråldosen utan att undersökningens kvalitet påverkas. Vid optimering inom röntgendiagnostik balanseras patientstråldos mot bildkvalitet. Optimeringen kräver att man haOptimisation in diagnostic radiology requires accurate methods for determination of patient absorbed dose and clinical image quality. Simple methods for evaluation of clinical image quality are at present scarce and this project aims at developing such methods. Two methods are used and further developed; fulfilment of image criteria (IC) and visual grading analysis (VGA). Clinical image quality de

The argument in this paper is that Hobbes’ theory of freedom in Leviathan allows for four ways of being free to act – corporal freedom by nature, freedom from obligation by nature, the freedom to disobey, and the freedom of no-rule – each corresponding to a particular absence, some of which make sense only in the civil state. Contrary to what some have claimed, this complexity does not commit Hobb

It is still impossible to make an accurate, purely theoretical prediction of the free energy of a ligand binding to a protein in aqueous environment. The two main problems are the immense number of nuclear configurations contributing to the binding free energy and the impossibility to apply accurate quantum-chemical methods to such a large system, even for a single configuration. In this thesis, t

Popular Abstract in Swedish Artros är en av de vanligaste kroniska sjukdomarna och en av de främsta orsakerna till funktionshinder för människor världen över. Artros angriper ofta knä- och höftlederna och bryter ner det brosk som finns där. För den som drabbats av artros tar förloppet ofta många år, med successivt ökande smärtor och rörelsesvårigheter. Ofta upptäcks dessutom inte sjukdomen förrän Osteoarthritis (OA) is a common chronic disease and one of the major global causes for functional disabilities. The disease is characterized by loss and degradation of cartilage, commonly affecting the knees and hips. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a previously presented method for identification of early OA using magnetic resonance imaging (MRI). By quantifying the T1 p

BACKGROUND: Nearly a quarter of patients with locally advanced (T4 stage) or perforated colon cancer are at risk of developing peritoneal metastases, often without curative treatment options. We aimed to determine the efficacy of adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with locally advanced colon cancer.METHODS: This multicentre, open-label trial was done in nine hos

Introduction: Pancreatic cancer is a highly lethal disease with a close association between incidence and mortality. First-line (FL) palliative chemotherapy prolongs survival and alleviates cancer-related symptoms. However, the survival benefit of second-line (SL) treatment is uncertain, as studies fail to consistently show prolonged survival for any given SL treatment, and in the absence of progn

Background: The range of onset ages within some PSEN1 families is wide, and a few cases of reduced penetrance of PSEN1 mutations have been reported. However, published data on reduced penetrance have been limited to clinical histories, often collected retrospectively and lacking biomarker information. We present a case of reduced penetrance of the PSEN1 H163Y mutation in a carrier prospectively fo

Background We designed the EURAMOS-1 trial to investigate whether intensified postoperative chemotherapy for patients whose tumour showed a poor response to preoperative chemotherapy (≥10% viable tumour) improved event-free survival in patients with high-grade osteosarcoma. Methods EURAMOS-1 was an open-label, international, phase 3 randomised, controlled trial. Consenting patients with newly diag

This MSc Thesis’s main objective is to determine the impact of transformer inrush currents in the grid and develop a tool that helps E.ON Energidistribution AB evaluate transformer sizing. The motivation of E.ON is to have a more precise way to estimate the energization consequences of increasing the transformer size in the grid, since currently is being used a rule of thumb that relates the trans

Many new models of smartphones and small electronic devices are using their wireless charging feature as a key selling point. This is due to the convenience of cable-free charging as well as not requiring multiple power adapters for charging different devices. However, with the increasing use of devices having wireless charging capability, safety and efficiency issues arise. Safety concerns are cr

Purpose: Radiomics entails the extraction of quantitative imaging biomarkers (or radiomics features) hypothesized to provide additional pathophysiological and/or clinical information compared to qualitative visual observation and interpretation. This retrospective study explores the variability of radiomics features extracted from images acquired with the 0.35 T scanner of an integrated MRI-Linac.

Background and objective: There is an unmet need to avoid long-term morbidity associated with standard cytotoxic treatment for low-volume metastatic seminoma. Our aim was to assess the oncological efficacy and surgical safety of retroperitoneal lymph node dissection (RPLND) as treatment in a population-based cohort of metastatic seminoma patients with limited retroperitoneal lymphadenopathy. Metho

BACKGROUND: The scapular free flap has increasingly gained popularity as an alternative to the fibular free flap in osseous head and neck reconstruction. The present study aimed to evaluate their use in maxillomandibular reconstructions and examine surgical and patient outcomes.METHODS: Osseous head and neck defects reconstructed with an angular artery-based scapular flap or fibular flap from 2016

Background: Infants with congenital heart defects (CHD) are at risk for white matter brain injury. This novel rat pup model characterizes the systemic effects of intravasal cell-free hemoglobin and hyperoxia, hypothesizing that immature endogenous scavenging systems relate to increased vulnerability to conditions present during cardiopulmonary bypass (CPB).Methods: Plasma pharmacokinetics of cell-

Popular Abstract in Swedish I Sverige och Norden har elproduktion traditionellt skett med huvudsakligen vattenkraft och kärnkraft. Detta håller dock på att förändras i takt med en allt större vindkraftsutbyggnad. Vindkraften skiljer sig i vissa avseenden från de traditionella produktionsslagen, ett av dessa är hur anslutningen till elnätet är utformad. Detta innebär att vindkraften, sedd från näteTraditionally the predominant generation has been large synchronous generators providing the system inertia. Nowadays when wind power and other non-synchronously connected units displaces this synchronous generation, the system inertia is reduced. Hence higher rate of change of frequency and larger frequency deviations are expected. This thesis deals with the impact on rate of change of frequency

Important steps when requesting samples and/or data from the Malmö Cohorts Feel free to make an initial preliminary contact to get more information (see contact list below).   Apply for ethical approval. Only approvals by The Swedish Ethical Review Authority are accepted. Researchers from universities outside Sweden should contact us to make sure that an approval is already available, but if not,

https://www.malmo-kohorter.lu.se/malmo-cohorts - 2026-07-21

The Malmö Offspring Study started on March 1st, 2013 and aims to map family patterns behind major diseases on the basis of gene-environment interaction [5-7]. Finding patterns to different chronic diseases It is well known that a number of large chronic disease groups tend to congregate within certain families, but the reason for this is unknown. However, one knows that the purely genetic componen

https://www.malmo-kohorter.lu.se/malmo-offspring-study-mos-0 - 2026-07-21

LUCAT is the Lund University online staff directory and contains information about you, like title, telephone number, and placement. The information in LUCAT is used in all areas and by several systems. It is therefore important that the information in LUCAT is accurate and current. Update to be findableWithin the department, we use the information for IT support, display online contact informatio

https://www.biology.lu.se/internal/employment/lucat-our-online-staff-directory - 2026-07-21

Head: Karin Stenkula My research group is focused on experimental cell biology research within the diabetes and obesity field. The overall purpose of our research is to explore both normal adipose cell function and the cellular mechanisms causing impaired glucose- and lipid metabolism associated with insulin resistance and type 2 diabetes. At a single cell level, we have shown that the GLUT4 trans

https://www.ludc.lu.se/glucose-transport-and-protein-trafficking - 2026-07-21