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Popular Abstract in Swedish Prostatacancer är en mycket vanlig form av cancer, och det har visats att cirka hälften av alla män över 70 år har tumör i prostata. Prostatacancer är ofta en latent form av cancer, vilket innebär att den sällan ger kliniska symtom förrän i ett framskridet stadium. Sedan PSA testet började användas på 90-talet har antalet diagnostiserade fall av prostatacancer blivit alProstate cancer is currently the most common form of cancer in Sweden. Currently, the only biomarker used in the clinic is serum PSA, and there is a great need for new biomarkers that may increase the diagnostic and prognostic information so that better predictions can be made, and treatment may be tailored. Here, we have investigated two proposed biomarkers microseminoprotein-β (MSMB) and cystein

Prostate cancer (PCa) is one of the most common cancers in men and is the second leading cause of cancer-related deaths in the USA. In the United States, it is the second most frequently diagnosed cancer after skin cancer, and in Europe it is number one. According to the American Cancer Society, approximately 221,000 men in the United States would be diagnosed with PCa during 2015, and approximate

A combination of normal-incidence x-ray standing-wave (NIXSW) spectroscopy, x-ray photoelectron spectroscopy (XPS), scanning tunneling microscopy (STM), and density-functional theory (DFT) has been used to investigate the interaction of a number of phthalocyanine molecules (specifically, SnPc, PbPc, and CoPc) with the Ag(111) surface. The metal-surface distances predicted by the DFT calculations f

Many flying animals use both flapping and gliding flight as part of their routine behaviour. These two kinematic patterns impose conflicting requirements on wing design for aerodynamic efficiency and, in the absence of extreme morphing, wings cannot be optimised for both flight modes. In gliding flight, the wing experiences uniform incident flow and the optimal shape is a high aspect ratio wing wi

Atmospheric N deposition is known to severely impact forest ecosystem functioning by influencing soil biogeochemistry and nutrient balance, and consequently tree growth and overall forest health and biodiversity. Moreover, because climate greatly influences soil processes, climate change and atmospheric N deposition must both be taken into account when analysing the evolution of forest ecosystem s

Background and purpose With an ageing population and an increasing incidence of diabetes, reduction of the number of diabetes-related amputations becomes increasingly difficult to achieve and maintain. There is controversy in this respect regarding the degree of success. We started a multidisciplinary treatment program for diabetic foot ulcers in 1982, and have now assessed incidence rates of ampu

This dissertation contains three independent studies that analyze labor markets in transformation. They focus on two central elements of labor markets in developing countries: non-agricultural employment in the rural economy and informal employment in the urban economy. Rural non-agricultural employment (RNAE) is being increasingly emphasized as a potential pathway out of rural poverty for people

This dissertation explores intervention practices for children and young persons with developmental disabilities. It focuses especially health and medically related services provided by the local children habilitation centres (CHC: s), where everyday services are carried out by interprofessional teams of habilitation specialists.The objective was to critically examine the CHC as a human service or

Diabetes Mellitus is a chronic disease of impaired blood glucose control due to degraded or absent bodily-specific insulin production, or utilization. To the affected, this in many cases implies relying on insulin injections and blood glucose measurements, in order to keep the blood glucose level within acceptable limits. Risks of developing short- and long-term complications, due to both too high

Popular Abstract in Swedish Hjärtsvikt är en sjukdom som beror på att hjärtat inte kan pumpa ut tillräckligt med blod till kroppens vävnader. I Sverige drabbas årligen 30000 personer av hjärtsvikt, och prognosen är jämförbar med de vanligaste cancerformerna. Trots att det är så vanligt och allvarligt, saknas i dagsläget objektiva mått på hjärtsvikt – det finns alltså ingen ”linjal” för att mäta huHeart failure is a clinical syndrome characterized by an inability of the heart to meet the metabolic demands of the body. Approximately 1-2% of the population in the western society has the diagnosis, and the 5-year mortality rate is comparable with the common cancer diagnoses. The lack of reliable objective measures of heart failure motivates research in this direction. Blood flow is an essentia