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Haemophilia B (HB) is a rare inherited bleeding disorder caused by the deficiency of coagulation factor IX (FIX). The major clinical issues are bleedings, often targeting the joints, and the development of neutralising antibodies, i.e. inhibitors, to the FIX replacement therapy. Historically HB has been seen as identical to the more common haemophilia A (HA), i.e. deficiency of coagulation factor

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Under de senaste åren har det skett en förskjutning i forskningen från att försöka förstå vem som löper risk att bli radikaliserad, till att undersöka vad som gör att vissa individer har större benägenhet att bli radikaliserad. Känslor av exkludering, diskriminering och marginalisering har tidigare kopplats till extremistiska handlingar. Trots det finns det få empiriska studier som utforskar samba

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Accurate and timely mapping of inundation extents during flood periods is essential for disaster evaluation and development of rescue strategies. With unique advantages over the optical sensors (e.g., little effect of clouds, and observations at day and night), Synthetic aperture radar (SAR) sensors provide an important data source for mapping inundation, particularly during flood periods. Freely

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INTRODUCTION: Neurological complications after surgery for acute type A aortic dissection (ATAAD) increase patient morbidity and mortality. Carbon dioxide flooding is commonly used in open-heart surgery to reduce the risk of air embolism and neurological impairment, but it has not been evaluated in the setting of ATAAD surgery. This report describes the objectives and design of the CARTA trial, in

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AIMS/HYPOTHESIS: Genetic and environmental factors are believed to cause type 1 diabetes. The aim of this study was to investigate the influence of maternal BMI and gestational weight gain on the subsequent risk of childhood type 1 diabetes.METHODS: Children in the Swedish National Quality Register for Diabetes in Children were matched with control children from the Swedish Medical Birth Register.

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De senaste teknologiska framstegen har lett till skapandet av högspecialiserade system inom olika industrier, vilket möjliggör uppgifter som tidigare varit otänkbara. I takt med att den globala efterfrågan på hållbara och effektiva energilösningar ökar, har behovet av innovation inom teknik aldrig varit större. Dessa framsteg representerar transformativa förändringar som omformar hela sektorer. Fr

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Surface soil moisture (SM) is a crucial variable representing the water content in soil at the topmost soil layer. Accurate data of SM are essential for various purposes, including the monitoring of drought, vegetation modeling, weather forecasting, and agriculture management. Over the past decades, microwave remote sensing has been employed to estimate SM at large scales, with the Sentinel-1 sate

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Introduction Atrial fibrillation (AF) is a major risk factor for ischaemic stroke and transient ischaemic attack (TIA), and AF detection can be challenged by asymptomatic and paroxysmal presentation. Long-term ECG monitoring after ischaemic stroke or TIA is recommended by all major societies in cardiology and cerebrovascular medicine as a secondary prophylactic measure. However, data on stroke red

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Avhandlingen är en sammanläggning av fyra artiklar om universell utformning i praktiken. Att designa för alla människor är en vägledande princip som Sveriges riksdag och regering beslutat om som del av implementeringen av FN:s konvention om rättigheter för personer med funktionsnedsättning. Avhandlingen bidrar med kunskap om förståelse, genomförande och samskapande gällande universell utformning. The thesis is a compilation of four articles and deals with Universal design in practice. This concept for designing for all is according to the Swedish Parliament and Government a guiding principle for the society. It is part of the implementation of the UN Convention on the Rights of Persons with Disabilities. The thesis contributes with knowledge about the understanding, implementation and co-c

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Denna uppsats har undersökt rätten för en icke-skadad stat att vidta kollektiva kontraåtgärder enligt folkrättens statsansvarsregler. Kollektiva kontraåtgärder innebär att en icke-skadad stat (enligt Artikel 42 ARSIWA) kan vidta kontraåtgärder mot en annan stat, när den staten brutit mot förpliktelser erga omnes (partes), även kallade kommunitära normer (på engelska communitarian norms). Sådana föThis thesis has examined the right of a non-injured state to take collective countermeasures under international state responsibility law. The concept of collective countermeasures refers to countermeasures that are taken by non-injured states (in the sense of Article 42 ARSIWA) in response to breaches of obligations erga omnes (partes), otherwise referred to as communitarian norms. Such obligatio

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The textile industry represents a major economic sector with millions employed. With over 200 trillion litres of water consumed each year, it is responsible for a tenth of global emissions, dwarfing aviation and maritime shipping, combined. The wastewater generated is predominantly non-biodegradable, constituting a complex matrix of various contaminants that have long-lasting effects on aquatic an