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Linkage disequilibrium (LD), the nonrandom occurrence of alleles in haplotypes, has long been of interest to population geneticists. Recently, the rapidly increasing availability of genomic polymorphism data has fueled interest in LD as a tool for fine-scale mapping, in particular for human disease loci(1). The chromosomal extent of LD is crucial in this context, because it determines how dense a
Topological qubits based on Majorana Fermions have the potential to revolutionize the emerging field of quantum computing by making information processing significantly more robust to decoherence. Nanowires are a promising medium for hosting these kinds of qubits, though branched nanowires are needed to perform qubit manipulations. Here we report a gold-free templated growth of III-V nanowires by
The realization that the extraction and combustion of fossil fuels is having serious effects on the environment and the climate, together with the ever-growing need for fuels, has led to the development of the concept of the biorefinery. Biorefineries are refineries in which fossil resources, such as oil, are replaced by renewable biomaterials to produce biofuels and biochemicals. Non-edible bioma
The majority of research in second language acquisition has traditionally focused on classroom-based, instructed learning. However, with the spread of new technologies and the concomitant globalisation of popular culture, informal second language practices (ISLPs; e.g. watching films and television, using social media, or playing video games in another language) are increasingly becoming part of t
The Inter- American Court of Human Rights has developed an interpretative approach in the recent years that considers all international instruments that deliver protection to human beings as part of the same legal system, that is, the corpus juris of international human rights law. Consequently, different branches of international law, such as international humanitarian law, refugee law, consular
A dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, operator-dependent image quality, and subjective image sampling methods have led to difficulty in establishing robust diagnostic measures relating to the progression of diabet
The centrality dependence of the mean charged-particle multiplicity as a function of pseudorapidity is measured in approximately 1 (Formula presented.) b (Formula presented.) of proton–lead collisions at a nucleon–nucleon centre-of-mass energy of (Formula presented.) (Formula presented.) using the ATLAS detector at the Large Hadron Collider. Charged particles with absolute pseudorapidity less th
Before industrialisation the Nordic countries (Denmark, Finland, Norway and Sweden) were part of Europe's poor periphery, but over the last century these countries have become some of the richest in the world. This article analyses the origins of Nordic growth from the late nineteenth century, focusing on a previously neglected topic: the role of transportation. We argue that transportation, and m
Deuteration of biomolecules has a major impact on both quality and scope of neutron scattering experiments. Cholesterol is a major component of mammalian cells, where it plays a critical role in membrane permeability, rigidity and dynamics, and contributes to specific membrane structures such as lipid rafts. Cholesterol is the main cargo in low and high-density lipoprotein complexes (i.e. LDL, HDL
This article examines how subsidiarity can limit the exercise of EU procedural criminal law competence. It argues for a narrow understanding of subsidiarity, suggesting that EU procedural criminal law legislation can only be directed at problems which are of a cross-border nature. By analysing a specific piece of EU legislation, the new Victims Directive, it is shown how the subsidiarity principle
We present charged-particle distributions sensitive to the underlying event, measured by the ATLAS detector in proton-proton collisions at a centre-of-mass energy of 13 TeV, in low-luminosity Large Hadron Collider fills corresponding to an integrated luminosity of 1.6 nb−1. The distributions were constructed using charged particles with absolute pseudorapidity less than 2.5 and with transverse mom
Changes to agricultural systems in Sub-Saharan Africa are subject to a wide range of drivers, often resulting in rapid and nonlinear dynamics. Such dynamics are however rarely recognized in studies of trends and drivers, which usually rely on assumptions of gradual progressions, and often using highly aggregated data. This paper addresses this lack of recognition and understanding of nonlinear pro
