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Here, we summarise the results after carrying out a large survey regarding the assessment of vascular alterations, both vessel changes and vascular lesions in an inter-laboratory setting. In total, 32 neuropathologists from 22 centres, most being members of BrainNet Europe (BNE), participated by filling out a questionnaire with emphasis on assessment of common vascular alterations seen in the brai

Popular Abstract in Swedish För att förse en byggnad med rätt luftkvalitet och temperatur behövs ett inneklimatsystem som i denna avhandling är ett samlingsnamn för ventilations-, värme- och kylsystem. Hittills har val av inneklimatsystem i byggnader mest baserats på en lägsta initialkostnad. Med ett livscykel-perspektiv borde de totala kostnaderna och miljöpåverkan från systemen kunna minskas. MoThe indoor climate system, which serves a building with a proper indoor air quality and thermal comfort, has been predominantly designed based on the initial cost. A life cycle approach could improve both the economic and environmental performance since the energy use could decrease. There has been a lack of knowledge, models and tools for determining the life cycle cost (LCC) for an indoor climat

On 7 December 1975 Indonesian troops invaded the former Portuguese colony of East Timor, which had unilaterally declared itself independent on 28 November the same year. The immediate background to the Indonesian invasion of East Timor was that the old regime in Portugal was overthrown in April 1974, resulting in a decolonisation programme for Portugal's colonies. Immediately after the invasion In

Genetic engineering has been used for fusion of the peptide tag, Trp-Pro-Trp-Pro, on a protein to study the effect on partitioning in aqueous two-phase systems. As target protein for the fusions the cellulase, endoglucanase I (endo-1,4-β-d-glucan-4-glucanohydrolase, EC 3.2.1.4, EGI, Cel7B) of Trichoderma reesei was used. For the first time a glycosylated two-domain enzyme has been utilized for add

The increasing emissions of carbon dioxide from fossil fuel burning are today thought to be one of the main contributors to global warming. At the same time, developing countries are striving for an increased welfare and burning more fossil fuel, which in turn is augmenting the greenhouse gas effect. In this thesis the current understanding of the connection between greenhouse gases and the climat

Popular Abstract in Swedish Gliom är en familj av hjärntumörer som är graderade beroende på hur snabbt och på vilket sätt de växer. Grad IV även kallad glioblastoma multiforme, är den mest elakartade av dessa. Patienter har en medelöverlevnadsprognos på ca 12 månader med behandling, såsom kirurgi, kemo- och strålningsterapi. Tumörerna är heterogena, vilket innebär att celler har flera typer av mutGliomas are neoplasms arising in the central nervous system (CNS), and constitute the most common primary brain tumor. They are classified depending on the grade and morphology, from grade I, pilocytic astrocytoma, to grade IV, glioblastoma multiforme (GBM). Glioblastomas constitute a great challenge in treatment due to their disseminating nature. Classical treatments such as surgery, radiation th

Popular Abstract in Swedish Idag lagras allt fler kartor digitalt och nya metoder krävs för att förbättra denna digitala hantering. Ett område som studerats under senare tid är automatiska metoder för kartografisk generalisering. Kartografisk generalisering innebär att man förenklar informationen i en karta för att göra den mer lättläst i den önskade skalan. Denna avhandling beskriver en optimerinCartographic generalisation is the process of simplifying a representation to suit the scale and purpose of a map. As such, generalisation has always been a central part in map production. This thesis is a contribution to the ongoing work on automating cartographic generalisation. Two topics are treated: optimisation methods in graphic generalisation, and propagation of updates between cartographi

Popular Abstract in English We won’t give up Anatolia! Shouting this slogan, thousands of villagers marched towards Ankara, protesting against the projects that threaten to channel Anatolian rivers into hydro-power plants. The majority of demonstrators did not reach Ankara. The police stopped them at the city gates for disturbing the public order: hydroelectricity development is a national prioritPrivate Rivers is a study of contested processes whereby use rights to water are privatised for electricity production. It engages with the issues of renewable energy solutions and the sustainability of run-of-river hydro projects in Turkey by investigating the connection between these policies and justice for rural populations, whose livelihood depends on the rivers. Since 2001, water privatisati

Popular Abstract in Swedish Självmord och självmordsförsök orsakar mycket lidande för många människor i vårt samhälle. I Sverige begår ungefär 1800 personer självmord varje år. De flesta av dessa personer hade vid tiden för självmordet en psykisk sjukdom. Man har funnit att åtminstone hälften av dessa personer hade en depressionssjukdom, minst en fjärdedel hade alkoholproblem och c:a 5% led av schA suicide attempt is one of the most powerful predictors of eventual suicide. The aim of this thesis was to investigate the social situation, including social support of suicide attempters. One part of the investigations concerned patients admitted to a psychiatric ward following a suicide attempt. Another part concerned significant others (SOs) of suicide attempters, interviewed directly after th

Popular Abstract in Swedish Att kunna lokalisera och bedöma en partner är en av de, evolutionärt sett, viktigaste egenskaperna hos alla sexuellt reproducerande organismer. För att möjliggöra detta använder sig ett djur sig av olika (visuella, taktila, akustiska och kemiska) signaler för inomartskommunikation. Jag har genom att studera kemiska signaler för inomartskommunikation (s.k. feromoner) hoLocating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. This is made possible by use of conspecific signals picked up by one or several sensory systems, the most well investigated bei

A committee has to address a complex question, the answer to which requires answering several sub-questions. Two different voting procedures can be used. On one procedure, the committee members vote on each sub-question and the voting results then are used as premises for the committee’s conclusion on the main issue. This premise-based procedure (pbp) can be contrasted with the conclusion-based pr

Popular Abstract in Swedish Tillväxthormon (GH) är ett hormon som produceras och insöndras stötvis från hypofysen. GH-insöndringen styrs av stimulerande och hämmande signaler från hypothalamus, men hämmas även av sin egen insöndring. GH produceras under hela livet men mängden insöndrat hormon sjunker med stigande ålder. Under barn- och ungdomsåren har GH en viktig funktion att stimulera längdtillvA risk for premature atherosclerosis and increased cardiovascular mortality has been reported in adult patients suffering from growth hormone deficiency (GHD) and receiving conventional hormone substitution without growth hormone (GH) replacement. GHD patients are resistant to insulin, which is a potential risk factor for cardiovascular mortality. Insulin resistance can develop from an unfavourabl

The use of restricted access media and other stationary phases for clean-up and trace enrichment of environmental samples coupled on-line to liquid chromatography using diode array detection as well as thermospray MS is described. This on-line configuration was compared with commercially available ELISAs for the determination of triazines in complex matrices, showing superior precision and accurac

Surfaces subjected to rolling and sliding contacts may suffer from contact fatigue. The cam and roller follower mechanism is a typical rolling and sliding contact. This thesis deals with the running in aspects to avoid high stress variation that leads to fatigue wear and the aspect of what happens to indentation damages that occurs on the surface if there are any particles in the lubricant. The pa

This paper describes the distribution of accusative case and discusses the nature of the nominative / accusative distinction in the standard Germanic languages. In addition, it illustrates and discusses the well-known fact that inherent accusatives and certain other types of accusatives do not behave in accordance with Bruzio’s Generalization. In spite of these Non-Burzionian accusatives, there is