Sökresultat

Susceptibility to lung cancer may in part be attributable to inter-individual variability in metabolic activation or detoxification of tobacco carcinogens. The glutathione S-transferase M1 (GSTM1) genetic polymorphism has been extensively studied in this context; two recent meta-analyses of case-control studies suggested an association between GSTM1 deletion and lung cancer. At least 15 studies ha

The structural effect on the metal-to-ligand charge transfer (MLCT) excited-state lifetime has been investigated in bis-tridentate Ru(II)-polypyridyl complexes based on the terpyridine-like ligands [6-(2,2'-bipyridyl)](2-pyridyl)methane (1) and 2-[6-(2,2'-bipyridyl)]-2-(2-pyridyl)propane (2). A homoleptic ([Ru(2)(2)](2+)) and a heteroleptic complex ([Ru(ttpy)(2)](2+)) based on the new ligand 2 hav

Monocot residues such as corn stover and straw are often not fully exploited and constitute a potential substrate for bioethanol production. However, a number of factors such as high enzyme loadings make large-scale utilization economically difficult. Addition of non-ionic surfactants and poly(ethylene glycol) to enzymatic hydrolysis of various lignocellulosic substrates has been found to increase

The collections of fungus gnats by Johan Wilhelm Zetterstedt (1785-1874), lodged in the Museum of Zoology in Lund, Sweden, are examined for all species belonging in the tribe Exechiini Edwards. The majority of the material was collected in Fennoscandia, mainly in Sweden, in the first half of the 19(th) century. Altogether 37 species of the tribe Exechiini could be safely identified. Three addition

As coexisting vestibular and cochlear lesions are of etiological importance, evaluation of children with congenital or early acquired hearing impairment (HI) should include vestibular assessment. A rotation test requires specific equipment and allows only detection of bilateral vestibular impairment. An impulse or head thrust test allows assessment of one ear at a time, detects more pronounced cal

A new member of the human cystatin multigene family has been cloned from a genomic library using a cystatin C cDNA probe. The complete nucleotide sequence of a 4.3-kilobase DNA segment, containing a complete gene with structure very similar to those of known Family 2 cystatin genes, was determined. The novel gene, called CST4, is composed of three exons and two introns. It contains the coding info

Objective. Ankylosing spondylitis (AS) is a progressive, debilitating disease with complex symptoms, unclear etiology and pathogenesis, and difficult diagnosis. Current imaging methods are useful in diagnosing AS and other spondyloarthropathies, and are frequently used in investigations of sacroiliitis. The radiographic diagnosis of sacroiliitis has large interobserver variations. Computed tomogra

Lower urinary tract (LUT) smooth muscle can be relaxed by drugs that increase intracellular concentrations of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). Both of these substances are degraded by phosphodiesterases (PDEs), which play a central role in the regulation of smooth muscle tone. The distribution and functional significance of PDE enzymes vary in differ