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Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor

Popular Abstract in Swedish I avhandlingen försöker jag visa hur polis, socialtjänst, rättsväsen, massmedia, olika intressegrupper, allmänhet och inte minst ungdomar själva skapar föreställningar om vad som är ett ungdomsproblem. De rutiner som de olika organisationernas aktörer utvecklar och det sätt som ungdomar och vi övriga "pratar" om ungdomsproblem bidrar till att den framställda bilden som The main aim of my dissertation is to investigate som conceptions, power relations, and practices in the discourse of youth problems. I have studied some of the actors that are involved in the social constructing of the "juvenile delinquent" such as the police, the judical system, the social service, the media, the general public and last but not least, the young people themselves. The bulk of my

In this thesis, the importance of cobalt and humic substances of terrestrial origin for the growth of some bloom-forming marine phytoplankton species is examined. Cobalt (Co) is considered an essential and potentially limiting trace metal for phytoplankton growth and is needed for the synthesis of vitamin B12. Since Co can be mobilised from soils at low pH values, acidification may have led to an

We are constantly reminded of the problem of evil. There are a number of models to cope with theodicy, but the problem with most of them is that, in different ways, they tend to legitimate evil and accuse the victims. In this article it is suggested that theodicy may serve as a hermeneutical key when reading often marginalised or misunderstood text belonging to the Jewish and Christian traditions.

Basic statistics courses for engineering students often focus on general applications in engineering, using course literature intended for ‘engineers’. However, these students are not a homogeneous group, and the differences among engineering programmes appear to be increasing. One way to meet the challenge of the diversity of needs within a discipline is to adapt the courses for different program

Parabolic planar compound refractive lenses (CRLs) made from glassy carbon by means of laser ablation are presented. They have radii of curvatures of 5 and 200 mu m and geometric apertures of 40 and 900 mu m, respectively. The numbers of biconcave elements in the CRLs were 4, 7, and 200. The planar lenses allow formation of a linear focus of length comparable with the depths of their profiles. Usa

Stratospheric ozone levels are near their lowest point since measurements began, so current ultraviolet-B (UV-B) radiation levels are thought to be close to their maximum. Total stratospheric content of ozone-depleting substances is expected to reach a maximum before the year 2000. All other things being equal, the current ozone losses and related UV-B increases should be close to their maximum. I

Remnants of more than 3 million transposable elements, primarily retroelements, comprise nearly half of the human genome and have generated much speculation concerning their evolutionary significance. We have exploited the draft human genome sequence to examine the distributions of retroelements on a genome-wide scale. Here we show that genomic densities of 10 major classes of human retroelements

The Transition Radiation Tracker (TRT) sits at the outermost part of the ATLAS Inner Detector, encasing the Pixel Detector and the Semi-Conductor Tracker (SCT). The TRT combines charged particle track reconstruction with electron identification capability. This is achieved by layers of xenonfilled straw tubes with periodic radiator foils or fibers providing TR photon emission. The design and choic

The gene responsible for X-linked agammaglobulinemia (XLA) has been recently identified to code for a cytoplasmic tyrosine kinase (Bruton's agammaglobulinemia tyrosine kinase, BTK), required for normal B cell development. BTK, like many other cytoplasmic tyrosine kinases, contains Src homology domains (SH2 and SH3), and catalytic kinase domain. SH3 domains are important for the targeting of signal

Popular Abstract in Swedish I denna avhandling studeras skolsituationen för elever med båda föräldrarna födda utomlands. Samband mellan elevernas bakgrund, övriga faktorer som i tidigare forskning visat sig betydelsefulla och skolresultat identifieras och analyseras. Studien utgår från de data som insamlades inom ramen för "Det nationella programmet för utvärdering", som genomfördes 1992. Utvärder