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Protein structural flexibility is important for catalysis, binding, and allostery. Flexibility has been predicted from amino acid sequence with a sliding window averaging technique and applied primarily to epitope search. New prediction parameters were derived from 92 refined protein structures in an unbiased selection of the Protein Data Bank by developing further the method of Karplus and Schulz

By a mixture density is meant a density of the form pi(mu) (.) = f pi(theta) (.) x mu(d theta), where (pi(theta))(theta Theta is an element of) is a family of probability densities and mu is a probability measure on Theta. We consider the problem of identifying the unknown part of this model, the mixing distribution A, from a finite sample of independent observations from pi(mu). Assuming that the

The influence of subphase characteristics (ionic strength, pH, and the presence of bridging cations) on the conformation and lateral orientation of the hydrophobic polypeptide poly-(L)-leucine (p-leu) has been investigated at the air-water interface with the surface film balance technique as well as with Brewster angle microscopy (BAM). In addition, Langmuir-Blodgett films of p-leu deposited on qu

A laboratory procedure is described for measuring methane potentials of organic solid waste. Triplicate reactors with 10 grams of volatile solids were incubated at 55 degreesC with 400 ml of inoculum from a thermophilic biogas plant and the methane production was followed over a 50-day period by regular measurements of methane on a gas chromatograph. The procedure involves blanks as well as cellul

The flame propagation in a spark-ignition engine has been studied using laser-induced fluorescence (LIF) of species formed during the first ignition stage of hydrocarbon combustion. The detected two-dimensional LIF images showed the distribution of unburned regions. For the excitation, two Nd:YAG lasers operating at 355 mn were used for two consecutive measurements within the same engine cycle wit

Starting from the assumption that travelling has negative consequences for the ecological environment, this study deals with travel behaviour in Malmö. The study focuses on how households with different demographic and socio-economic characteristics and transport needs, confronted with different restrictions and possibilities in the surrounding structures, choose to travel in their everyday life.

Alpha-1 microglobulin (alpha(1)m), a lipocalin, is an evolutionarily conserved immunomodulatory plasma protein. In all species studied, alpha(1)m is synthesized by hepatocytes and catabolized in the renal proximal tubular cells. alpha(1)m deficiency has not been reported in any species, suggesting that its absence is lethal and indicating an important physiological role for this protein To clarify

Popular Abstract in Swedish Beslutsinkompetenta patienter behöver en ställföreträdande beslutsfattare som kan fatta vårdbeslut för deras räkning. En av de etiska frågor som aktualiseras i detta sammanhang är vilka riktlinjer som bör gälla för sådant beslutsfattande. Enligt ?the Substituted Judgment Standard? (SJS) bör en ställföreträdare fatta det beslut som patienten själv hade fattat, om denne h

Movement data are analyzed to elucidate principles of articulator coordination. Procedures for tracking articulator gestures from x-ray motion films, and results obtained from Swedish and Bulgarian work are reported in Wood [J. Phon. 19, 281–292 (1991), Proc. 3rd Congress I.C.P.L.A., 191-200, Helsinki (1994), Proc. 13th I.C.Ph.Sc., Vol. 1, 392–395, Stockholm (1995), J. Phon. (in press)]. Coarticul