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Christopher Polhem: Technical innovations and the metaphorical mind

Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a

Christopher Polhem: Tekniska innovationer och det metaforiska tänkandet

Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a

The role of B cells and Th2 cytokines in physiological and pathological inflammation

Popular Abstract in Swedish Vårt immunförsvar har utvecklats genom evolutionen för att kunna motstå infektioner från diverse mikrober (parasiter, bakterier, virus). Kroppen svarar då med en inflammationsrespons för att kunna bekämpa infektionen. Immunsvaret kan delas upp i det icke specifika immunsvaret, bestående av bl.a. fagocyterande celler samt det specifika immunsvaret, bestående av sk T och The CD4+ T cells have an important role in inflammation. Based on the local cytokine milieu, these cells can differentiate into either a Th1 population promoting cellular immunity or Th2 population involved in humoral immunity. Th2 cells produce the anti-inflammatory cytokines IL-4 and IL-10, which might have a protective role in autoimmune diseases like rheumatoid arthritis (RA) and multiple scle

Stellar Abundances in Giant Stars in the Metal-Rich Globular Cluster NGC 6528

We present the first results of a detailed abundance analysis, based on VLT observations, of giant stars in the very metal-rich globular cluster NGC 6528. We will be able to tie the horizontal branch abundances (see e.g. Carretta et al. 2001) to those of the more luminous giants (see CMDs). For the very similar cluster NGC 6553 studies of different types of stars have yielded very disparate result

Extracorporeal immunoadsorption

Popular Abstract in Swedish Bakgrund Kroppen har många olika försvarsmekanismer för att skydda sig mot angrepp av olika slag. Bland försvarsmekanismerna i immunförsvaret finns förmågan att bilda antikroppar. Antikroppar, eller immunglobulin, är lösliga protein och består av fyra polypeptidkedjor som hålls samman av svavelbindningar. Dessa kedjor har en variabel ände som ger upphov till molekylensAntibodies are important protein structures in the immunological defence. Occasionally the regulation of the production of these antibodies fails and antibodies directed against self structures are produced in large scale. Antibody production can also complicate or make transfusions and transplantations impossible. Purified protein A from Staphylococcus aureus immobilised to beaded agarose can ads

Are there general principles of community law affecting private law?

The purpose of conference of the Swedish Network for European Legal Studies in Stockholm on March 22 and 23 was to detect and evaluate general principles of European community law. The conference was a follow up to the 1999 Malmö conference on the subject and the question was if there had been any new development. In 1999 general principles of Community law was discussed from the perspective of hu

Comparison of different powered-wheelchair control modes for individuals with severe motor impairments

This paper presents the preliminary evaluation of different powered-wheelchair control modes for individuals with severe motor impediments. To this end, a C400 Permobil wheelchair has been updated with a control command communication interface and equipped with a scanning laser sensor to carry out the automation algorithms that are part of the robot operating system framework. A pilot test was per

Engineering Work - On Peer Reviewing as a Method of Horizontal Control

The existing research has produced a useful palette of ideas that help us make sense of the phenomenon of organizational control. But there is a trend that hampers the interpretative possibilities: a heavy bias towards vertical forms of control. It is frequently assumed that the control that operates in organizations has its origin in the actions of managers. This assumption is especially problema

Origin and evolution of the mitochondrial proteome

The endosymbiotic theory for the origin of mitochondria requires substantial modification. The three identifiable ancestral sources to the proteome of mitochondria are proteins descended from the ancestral alpha -proteobacteria symbiont, proteins with no homology to bacterial orthologs, and diverse proteins with bacterial affinities not derived from alpha -proteobacteria. Random mutations in the f

Exploring the Multiple Roles of Lund University in Strengthening Scania's Regional Innovation System: Towards Institutional Learning?

Universities are increasingly seen as potential contributors to regional innovative capacity by serving as local knowledge conduits, bringing global state-of-the-art science and technology into the region. In practice, however, more active university engagement with their regional innovation systems is not as straightforward as it may seem. The article uses examples from a successful case by which

Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

Age at menarche is a strong and consistent predictor of breast cancer risk in the general population, but has not been well studied in women with a family history of breast cancer. We conducted this study to examine whether the presence of a deleterious BRCA1 or BRCA2 mutation influences age at menarche and to investigate whether or not there is an association between age at menarche and the risk

Blue stragglers as stellar collision products: the angular momentum question

We investigate the structure and evolution of blue straggler stars, which were formed from direct stellar collisions between main-sequence stars in globular clusters. In particular, we look at the rotational evolution of the products of off-axis collisions. As found in previous work, such blue stragglers initially have too high an angular momentum to contract down to the main sequence. We consider