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Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos kvinnor i Sverige, men även män kan drabbas. Hos män är det dock en mycket ovanlig cancerform. I Sverige insjuknar cirka 40 män per år av bröstcancer jämfört med cirka 8000 kvinnor per år. Bröstcancer hos män och kvinnor är på många sätt lika. Till exempel är sjukdomstecknen desamma och visar sig oftast som en knöl eller knCancer is today a major healthcare problem worldwide. There are many forms of cancer, which is a genetic disease, believed to result from a multistep process with genetic and epigenetic changes accumulating over time. Breast cancer is one of the most common forms of cancer in women, while it is much more rare in men. Male breast cancer (MBC) exhibits both similarities and differences with female b

The authors have collected data for the silver market, shedding light on market size, stocks in society and silver flows in society. The world supply from mining, depletion of the remaining reserves, reducing ore grades, market price and turnover of silver was simulated using the SILVER model developed for this study. The model combines mining, trade markets, price mechanisms, populations dynamics

This paper is the fourth in a series discussing experiences in applying the Strategic Systemic Thinking (SST) framework. The framework was originally proposed for the purpose of supporting contextual analysis into complex problem spaces as part of information systems analysis. Previous papers have dealt with an application supporting strategic development of work in an academic university departme

Utilizing time series modeling entails estimating the model parameters and dispersion. Classical estimators for autocorrelated observations are sensitive to presence of different types of outliers and lead to bias estimation and misinterpretation. It is important to present robust methods for parameters estimation which are not influenced by contaminations. In this article, an estimation method en

Highly protonated histone-derived peptides impede a sufficient mass spectrometry (MS) -based epigenetic analysis since their relatively low m/z due to a high degree of proton addition to peptides would difficult to analyze the resulting complex MS/MS spectra. In order to reduce the degree of protonations, we have developed a new interface, the IVU, in which peptides are ionized under a vaporized o

The hypothesis that human reasoning and decision-making can be roughly modeled by Expected Utility Theory has been at the core of decision science. Accumulating evidence has led researchers to modify the hypothesis. One of the latest additions to the field is Dual Process theory, which attempts to explain variance between participants and tasks when it comes to deviations from Expected Utility The

Migraine is a neurovascular disorder characterized by recurrent unilateral headaches accompanied by nausea, vomiting, photophobia and phonophobia. Current theories suggest that the initiation of a migraine attack involves a primary event in the central nervous system (CNS), probably involving a combination of genetic changes in ion channels and environmental changes, which renders the individual m

There is overwhelming evidence that hypertension is an important risk factor for both macrovascular and microvascular complications in patients with diabetes, but the problem remains to identify appropriate goals for preventive therapies. A number of guidelines (the European Society of Cardiology (ESC)/European Association for the Study of Diabetes (EASD) 2007, the Joint National Committee (JNC)-V

Hyperbaric oxygen therapy (HBO) is a short-term, high-dose oxygen inhalation and diffusion therapy, delivered systemically through airways and blood under high pressure using hyperbaric chambers. HBO stimulates angiogenesis, reduces edema, augments granulation tissue formation by enhancing fibroblasts, and improves leukocyte function by elevating the partial pressure of oxygen in tissue. The numbe

Afforestation has been proposed as a strategy to mitigate the often high greenhouse gas (GHG) emissions from agricultural soils with high organic matter content. However, the carbon dioxide (CO2) and nitrous oxide (N2O) fluxes after afforestation can be considerable, depending predominantly on site drainage and nutrient availability. Studies on the full GHG budget of afforested organic soils are s