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A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure
Wood modification as a tool to understand moisture in wood
EU Law and the Discretion of Private National Decision-Makers, in Light of the Court’s Judgment in Case C-22/18, TopFit and Biffi
This contribution aims to introduce the reader to a judgement from the Court of Justice which seems to broaden the scope of application of EU free movement rules to private regulatory bodies in two ways. On the one hand, this judgment expands our understanding of what type of private regulation can fall within this scope. On the other hand, it shows that EU law requires a private prior authorisati
Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors
Age-specific mortality and short-term changes in the standard of living : Sweden, 1751-1859
Hormonal male contraception
The demand for availability of efficient and safe contraceptive methods is strengthened by the predic-tions made by the United Nations regarding the future growth of the human population. So far, women are not only the main victims of the unsafe procedures related to terminating unwished pregnancies but do also carry the main responsibility for family planning. There is a significant desire among
The Pahlavis and the Other Side of the Coins
User evaluation of a national e-library for standardized chemotherapy regimens
An e-library for standardized chemotherapy regimens has been developed and is, since 2015, available as a national resource for healthcare staff and patients in cancer treatment in Sweden. The library was developed in a user-centered design process and is now evaluated to understand how it is used and if it is used in the intended way. This paper presents the e-library in brief together with preli
Limonene and linalool hydroperoxides review : Pros and cons for routine patch testing
Limonene and linalool are among the most common fragrance terpenes used in everyday products. They are pre-haptens, forming hydroperoxides (Lim-OOHs, Lin-OOHs) upon oxidation and inducing frequent positive patch test reactions in patients with dermatitis, and yet they are not routinely tested in Europe. This review evaluates current patch testing with Lim-OOHs and Lin-OOHs by asking whether hydrop
Crystallisation of the Glycyl-tRNA synthetase from thermus thermophilus and initial crystallographic data
The glycyl-tRNA synthetase from Thermus thermophilus is a dimer of molecular mass 115 kDa, which has been crystallised using the vapour diffusion method from 5 to 7% polyethylene glycol 6000, 0.8 to 1.4 M NaCl at protein concentrations of 2 to 8 mg/ml. Nucleation is carried out at 4°C and crystals are subsequently transferred to 15°C to maximise growth. Crystals are truncated rhombohedra measuring
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Comparison of historical medical spending patterns among the BRICS and G7
The global biogeography of avian haemosporidian parasites is characterized by local diversification and intercontinental dispersal
The biogeographic histories of parasites and pathogens are infrequently compared with those of free-living species, including their hosts. Documenting the frequency with which parasites and pathogens disperse across geographic regions contributes to understanding not only their evolution, but also the likelihood that they may become emerging infectious diseases. Haemosporidian parasites of birds (
The Impact of Inter-Firm Collaborations on SME Internationalisation
Several studies have proposed that small- and medium-sized enterprises (SMEs) lack resources and experiential knowledge to internationalise to distant markets. The authors argue that SMEs can handle the lack of these tangible and intangible internal resources through external collaborations; they can achieve success in international markets by collaborating with business partners. The role of inte
Anomalous Schottky Signals from a Laser-Cooled Ion Beam
Estrogenic activity of surface waters using zebrafish- and human-based in vitro assays : The Danube as a case-study
Most in vitro reporter gene assays used to assess estrogenic contamination are based on human estrogen receptor α (hERα) activation. However, fish bioassays can have distinct response to estrogenic chemicals and mixtures, questioning the relevance of human-based bioassays for assessing risk to this species. In this study, zebrafish liver cells stably expressing zebrafish ERβ2 (ZELHβ2) and human br
Luminescence and vacuum ultraviolet excitation spectroscopy of cerium doped Gd3Ga3Al2O12 single crystalline scintillators under synchrotron radiation excitations
Experiences of meaning in garden therapy in outpatient psychiatric care in Sweden. A narrative study
Background: Support has been found for using garden therapy as form of intervention for clients with common mental disorders, but no consensus has been found for what contributes to perceived meaningfulness of garden therapy. Aims: To investigate whether participants perceived garden therapy as meaningful, and if so, what contributed to the meaningfulness. Material and methods: Narrative individua
Optimized generation of high resolution breast anthropomorphic software phantoms
Purpose: The authors present an efficient method for generating anthropomorphic software breast phantoms with high spatial resolution. Employing the same region growing principles as in their previous algorithm for breast anatomy simulation, the present method has been optimized for computational complexity to allow for fast generation of the large number of phantoms required in virtual clinical t
