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Unsolved Asymmetries and Complex Productive Structures in the Eurozone

The severity of the crisis in the Southern Eurozone countries is frequently attributed to inflated economies and reckless spending. Thus, it isn’t surprising that the main interpretation is that the crisis ought to be solved by decreasing government spending and lowering wages. This paper argues, instead, that one of the core underlying reasons for the severity of the crisis in the Southern Eurozo

Enabling Reuse in Extended Producer Responsibility Schemes for White Goods : Legal and Organisational Conditions for Connecting Resource Flows and Actors

Extended producer responsibility (EPR) schemes have proliferated across Europe and other parts of the world in recent years and have contributed to increasing material and energy recovery from waste streams. Currently, EPR schemes do not provide sufficient incentives for moving towards the higher levels of the waste hierarchy, e.g. by reducing the amounts of waste through incentivising the design

A Retardation Factor Considering Solute Transfer Between Mobile and Immobile Water in Porous Media

In advective-dispersive simulations of aquifers, retardation factors using linear adsorption isotherms are commonly employed to represent the adsorption-desorption process for solutes in soil. In particular, the retardation factors that use entire pore space (total porosity) or effective pore space (effective porosity) are widely used. Although another retardation factor that describes solute tran

Advances in immune therapies in hematological malignancies

Immunotherapy in cancer takes advantage of the exquisite specificity, potency, and flexibility of the immune system to eliminate alien tumor cells. It involves strategies to activate the entire immune defense, by unlocking mechanisms developed by tumor cells to escape from surrounding immune cells, as well as engineered antibody and cellular therapies. What is important to note is that these are t

High-frequency news sentiment and its application to forex market prediction

Financial news has been identified as an important alternative information source for modeling market dynamics in recent years. While most of the attention goes to stock markets, the foreign exchange (Forex) market, in contrast, is much less studied. Most of the existing text mining research for the Forex market combine news sentiment with other text features, making the contribution of each facto

Progress towards Clinical Use of iPS Cell Derived Therapies

A decade has passed since Shinya Yamanaka published his landmarking publication on how to produce pluripotent stem-cell-like cells and the term induced pluripotent stem cells, iPS cells, was coined. This past decade has been a decade devoted to pluripotent cells, scrutinizing molecular mechanisms in cell identity, and optimizing derivation methods, culture conditions and characterization methods t

Modeling psychiatric disorders : from genomic findings to cellular phenotypes

Major programs in psychiatric genetics have identified >150 risk loci for psychiatric disorders. These loci converge on a small number of functional pathways, which span conventional diagnostic criteria, suggesting a partly common biology underlying schizophrenia, autism and other psychiatric disorders. Nevertheless, the cellular phenotypes that capture the fundamental features of psychiatric diso

Evaluation of TRAP-sequencing technology with a versatile conditional mouse model

Gene expression profiling of various cell lineages has provided invaluable insights into the molecular mechanisms regulating cellular development and differentiation. However, in vivo molecular profiling of rare and interspersed cell populations, such as endothelial cells, has remained challenging. We have generated a versatile floxed translating ribosome affinity purification (TRAP) mouse model,

Can water cause brittle fracture failures of composite non-ceramic insulators in the absence of electric fields?

It was postulated in [1], based on experimental evidence, that brittle fracture failures of composite (non-ceramic) HV insulators could be caused by water and mechanical stresses. It was also claimed therein that the brittle fracture process was more likely to happen with water than acids. This postulation could be of major importance as its ramifications might affect the entire composite insulato

The Øresund bridge from imagination to innovation

After its inauguration in 2000, the Oresund bridge has allowed major mobility and flow of manpower, goods, and services between Sweden and Denmark. Was this the vision that Danes and Swedes have imagined over the past century and a half, when thinking of a bridge over the Sound? And, if so, why did it take more than one hundred years in order to start the construction of the øresundsförbindelsen?