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Activation of human B cells with the Moraxella catarrhalis IgD-binding protein MID
Popular Abstract in Swedish Moraxella catarrhalis är en bakterie som tillhör vår normala bakterieflora. Den är dock också en luftvägspatogen som kan orsaka öroninflammation hos barn, nedre luftvägsinfektioner hos vuxna och äldre, och bihåleinflammation hos både barn och vuxna. Intresset kring M. catarrhalis som patogen har ökat de senaste 20 åren, både på grund av ökat antal insjuknande personer oMoraxella catarrhalis is a respiratory tract pathogen that causes significant health problems, including acute otitis media in children, lower respiratory tract infections in adults and the elderly and sinusitis in both children and adults. The interest in M. catarrhalis bacteria has increased over the past 20 years, both because of the emergence of the bacteria as a human pathogen and because of
A Late Silurian extinction event and anachronistic period
Resurgence of microbialites and anachronistic facies in the aftermath of Phanerozoic extinction events has hitherto only been documented among the "major five." Based on the classical Silurian carbonate platform strata of Gotland, Sweden, a "minor" biotic event is herein for the first time related to a substantial increase in anachronistic facies. Strata deposited during and shortly after the Lau
Giving language a hand: gesture as a cue based communicative strategy *
Polymorphism and recombination events at the ABO locus: a major challenge for genomic ABO blood grouping strategies
The blood group ABO gene codes for a glycosyltransferase that adds the ultimate monosaccharide to a glycoconjugate and forms the A or B blood group specific antigen. The DNA structure of the three major alleles of the human blood group ABO system was first described in 1990. This review describes the subsequent developments, including the increasing number of variants of these common alleles and t
Distribution of preproatrial natriuretic peptide mRNA in rat brain detected by in situ hybridization of DNA oligonucleotides: enrichment in hypothalamic and limbic regions
The expression and distribution of mRNA encoding preproatrial natriuretic peptide (ppANP) in rat brain has been investigated by in situ hybridization of two 35S-labeled synthetic DNA oligonucleotides, based on a cDNA clone sequence that encodes rat ppANP. The highest relative concentrations of ppANP mRNA were detected in the medial preoptic hypothalamic nucleus ("anteroventral/third ventricle regi
Thin and Thick Disk Results for α-, r- and s-Process Elements
We present the first results from several ongoing studies of the stellara bundances, ages, and chemical trends in the long-lived dwarf stars in the solar neighborhood that belong to the thin and thick galactic disk.We confirm that the trends of α-elements in the thin and thick disk are distinct, and we also find that the thick disk show the typical signature of SN Ia contribution to the chemical e
Enzymatic metal-chelation by porphyrins
Popular Abstract in Swedish Vad har jag gjort de senaste åren? Och varför? Det är det många som har undrat. Så stundtals även jag. Vad jag skriver nedan syftar inte till att förklara detta, utan är bara ämnat som en kort introduktion. Jag har de senaste åren jobbat med gener och proteiner från både växter och bakterier. Både gener och proteiner är väldigt små saker, men även den minsta lilla sak This thesis deals with the structure and function of two different enzymes, ferrochelatase and magnesium chelatase, that catalyse similar reactions. When this work started, a three-dimensional model of ferrochelatase existed. Much was known about the enzyme, but some details remained unclear. The focus has been to establish where the metal and the porphyrin binds to the enzyme, and how they are pu
Vitreoscilla Haemoglobin. Genetic Fusions and Metabolic Characterisation
Popular Abstract in Swedish Genteknik innebär stora möjligheter att förändra och förbättra organismers egenskaper. Genom att i en organism föra in en främmande gen kan man ge den helt nya egenskaper som den aldrig skulle ha förvärvat på naturlig väg. Genmodifierade bakterier odlas idag industriellt i stora bioreaktorer för tillverkning av olika proteiner, till exempel insulin till diabetiker, humaVitreoscilla is an obligate aerobic bacterium living in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla expresses a homodimeric haemoglobin (VHb) when subjected to oxygen-limited conditions. In several organisms, expression of VHb has been shown to increase microaerobic cell growth and enhance oxygen-dependent cell metabolism. Moreover, the presence of V
Double Layer Forces: the Role of Molecular Solvents
The dielectric continuum model has rightfully been and continues to be a major workhorse for theory and modelling in Surface and Colloid Chemistry. Due to the implicit description of water, entering only as a scaling constant for charge-charge interactions, one would not expect it to work for short distances. However, considerable evidence has been accumulated over the years which shows that t
Bullied into it: bullying, power and the conduct of conduct
Determination of the b quark mass at the M-Z scale with the DELPHI detector at LEP
An experimental study of the normalized three-jet rate of b quark events with respect to light quarks events (light = l equivalent to u, d, s) has been performed using the CAMBRIDGE and DURHAM jet algorithms. The data used were collected by the DELPHI experiment at LEP on the Z peak from 1994 to 2000. The results are found to agree with theoretical predictions treating mass corrections at next-to-
Multicentre Patch Testing with Compositae Mix by the Swedish Contact Dermatitis Research Group.
Sesquiterpene lactone mix detects contact allergy to these compounds present in the plant family Asteraceae. This marker is present in many baseline series. An additional marker is Compositae mix, which is not present in many baseline series. To investigate whether this allergen should be inserted into the Swedish baseline series, sex dermatology centres representing the Swedish Contact Dermatitis
The agricultural revolution and the conditions of the rural poor, southern Sweden 1750–1860
Flame Sizes in a Small Scale Stack: Pilot Experiments
The need for nutrition support teams in pediatric units: A commentary by the ESPGHAN Committee on Nutrition
Coarse-grained modeling of proline rich protein 1 (PRP-1) in bulk solution and adsorbed to a negatively charged surface
Framväxten av en diagnos--synen på psykiska krigsreaktioner under 1900-talet med fokus på FN-svenskarna i Kongo 1960 - 64
Psychiatric casualties among soldiers constitute an inevitable part of modem warfare. For the past hundred years Medicine and Society have shown a growing interest in the combat reactions. The focus has shifted from an organic one towards a psychological and psychiatric perspective. Cultural, social, economical and political forces have influenced the scientific development from the Shell shock to
An efficient screening procedure detecting six novel mutations in the LDL receptor gene in Swedish children with hypercholesterolemia
Familial hypercholesterolemia (FH) is an autosomal semi-dominant disorder caused by defects in the low density lipoprotein receptor (LDLR) gene and is a well-documented risk factor for developing cardiovascular disease. The LDLR genes of five Swedish children with FH were examined in this study. Initial mutation screening was performed by denaturing gradient gel electrophoresis (DGGE) with enzymat
Maximizing the Use of Computational Resources in Multi-Camera Feedback Control
In vision-based feedback control systems, the time to obtain sensor information is usually non-negligible, and these systems thereby possess fundamentally different timing behavior compared to standard real-time control applications. For many image-based tracking algorithms, however, it is possible to trade-off the computational time versus the accuracy of the produced position/orientation estimat
