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Histidine oxidation in lytic polysaccharide monooxygenase
The lytic polysaccharide monooxygenases (LPMOs) comprise a super-family of copper enzymes that boost the depolymerisation of polysaccharides by oxidatively disrupting the glycosidic bonds connecting the sugar units. Industrial use of LPMOs for cellulose depolymerisation has already begun but is still far from reaching its full potential. One issue is that the LPMOs self-oxidise and thereby deactiv
Second-hand clothing markets and a just circular economy? Exploring the role of business forms and profit
Real-time fouling monitoring in food and biorefining industries – Needs and possibilities
Fouling is a constant challenge in membrane-based technologies. As conventional fouling monitoring and control methods are often based on process performance or product quality, they might reveal fouling so late that it has already damaged the membrane in severe and non-reversible way. Thus, surface sensitive online monitoring techniques capable of providing early warning capacity and information
Analysis and optimization by micro-beam X-ray diffraction of Al- GaInAs heterostructures obtained by Selective Area Growth for optoelectronic applications
Growth of AlGaInAs/InP heterostructures by Selective Area Metal Organic Vapour Phase Epitaxy is investigated in this paper using advanced characterization techniques and numerical modelling. Synchrotron radiation and X-Ray optics allow to have micro or sub-micro X-Ray probe. With this probe, it is possible to characterize our samples by X-Ray Diffraction on very restricted area. This technique was
Organisational Response Strategies to COVID-19 in the Sharing Economy
DIFFUSE RETINAL VASCULAR LEAKAGE AND CONE-ROD DYSTROPHY IN A FAMILY WITH THE HOMOZYGOUS MISSENSE C.1429G>A (P.GLY477ARG) MUTATION IN CRB1
PURPOSE: To describe a specific cone-rod dystrophy phenotype in a family with the homozygous c.1429G>A; p.Gly477Arg mutation in CRB1. The detailed phenotype of subjects with this specific mutation has not been described previously. METHODS: Clinical examination included full-field electroretinography and high-resolution and widefield retinal imaging and uveitis workup. Molecular genetic analysis i
Comparative Analysis of Flooding in Gothenburg, Sweden and Mumbai, India: A Review
To cope with flooding in cities, a combination of well working stormwater system and a resilient city is needed. As the future is uncertain, cities have to be built resilient, meaning that they can be flexible and adaptable, as it is not possible to protect the city from floods totally. Green areas in the city can provide resilience, as water can be led here e.g. during heavy rainfall. In this art
Moisture Buffer Value of Building Materials
Building materials and furnishing used in contact with indoor air may have a positive effect to moderate the variations of indoor humidity seen in occupied buildings. Thus, very low humidity can be alleviated in winter, as well as can high indoor humidity in summer and during high occupancy loads. This way, materials can be used as a passive means of establishing indoor climatic conditions, which
Some results on convolutional codes over rings
Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library
Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein-ligand struct
Novel strategies for the treatment of grass pollen-induced allergic rhinitis
Introduction: Allergic rhinitis (AR) affects over 20% of the population of Europe and the United States. Allergen immunotherapy (AIT) is currently the only form of treatment that affects symptoms and modifies the progression of disease. Established forms of AIT include subcutaneous (SCIT) and sublingual (SLIT) immunotherapy and are widely effective, yet only 2-9% of eligible patients undergo thera
The flicker fusion frequency of budgerigars (Melopsittacus undulatus) revisited
Decision making process for constructing low-energy buildings in the public housing sector in Sweden
The built environment accounts for a significant share of energy consumption and energy efficiency in this sector is important for the Swedish environmental objectives. Only a limited share of the total new construction of multifamily houses are constructed as low-energy buildings. Current building regulations lay down requirements for energy efficiency for new construction, and these will be tigh
The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy
HAMLET – A protein-lipid complex with broad tumoricidal activity
HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a tumoricidal protein-lipid complex with broad effects against cancer cells of different origin. The therapeutic potential is emphasized by a high degree of specificity for tumor tissue. Here we review early studies of HAMLET, in collaboration with the Orrenius laboratory, and some key features of the subsequent development of the HAML
Thermal stability and structural changes in bacterial toxins responsible for food poisoning
The staphylococcal enterotoxins (SEs) are secreted by the bacteria Staphylococcus aureus and are the most common causative agent in staphylococcal food poisoning. The staphylococcal enterotoxin A (SEA) has been associated with large staphylococcal food poisoning outbreaks, but newer identified SEs, like staphylococcal enterotoxin H (SEH) has recently been shown to be present at similar levels as S
