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Implementation of open source development practices within commercial settings can bring benefits such as improved source code quality, lower maintenance costs, and increased innovation. However, a widespread in-house implementation of the practices has not been observed. The goal of this research is to understand factors which hinder the implementation. For the purpose, development practices of a

Acute pancreatitis (AP) is a common clinical condition with an incidence of about 300 or more patients per million annually. About 10%-15% of patients will develop severe acute pancreatitis (SAP) and of those, 10%-30% may die due to SAP-associated complications. Despite the improvements done in the diagnosis and management of AP, the mortality rate has not significantly declined during the last de

We report whole-rock elemental and Sm-Nd isotope geochemical data from mafic-ultramafic supracrustal rocks from the Nunatak 1390 area in southern West Greenland. Additionally, we report the metamorphic temperature history for these rocks as derived from tourmaline thermometry on a tourmalinite inlier, as well as in situ U-Pb, Hf and O isotopic data from zircons extracted from tonalite-trondhjemite

Two new pyrazolate-based ligands, N'-[1-(3-acetyl-4-methyl-1H-pyrazol-5-yl)ethylidene]-2-(hydroxyimino)propanehydrazide (L1) and 5-[(E)-1-(2-{(E)-2-(hydroxyimino}propanoyl}hydrazono)ethyl]-4-methyl-1H-pyrazole-3-carboxylic acid (L2), were synthesized and studied for zinc(II) complexation. A set of pH-dependent UV/Vis measurements has been performed to determine the complex formation properties of

The secondary motion induced by flow through curves and bifurcations has been subject to investigation over long time due to its importance in physiological and technological applications. In contrast to the flow in a straight pipe, curvature leads to the formation of secondary flow which is often unsteady. Streamline curvature occurs also in bifurcating pipes leading to some corresponding seconda

The DEK oncogene is highly expressed in cells from most human tissues and overexpressed in a large and growing number of cancers. It also fuses with the NUP214 gene to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. Originally characterized as a member of this translocation, DEK has since been implicated in epigenetic and transcriptional regulation but its role in these proc

We have performed a systematic study of the entropy term in the MM/GBSA (molecular Mechanics combined with generalized Born and surface area solvation) approach to calculate ligand-binding affinities The entropies are calculated by a normal mode analysis of harmonic frequencies from minimized snapshots of molecular dynamics simulations. For computational reasons, these calculations have normally b

OBJECT: The aim is to describe the development of the scientific literature on dementia. METHODS: We present a quantitative, bibliometric study of the literature on dementia, based on Medline, covering 36 years (1974-2009). Two samples of references to dementia papers were retrieved: The main sample based on the MeSH term Dementia holds more than 88 500 references. We have compared the annual

Popular Abstract in Swedish Populärvetenskaplig sammanfattning: (Popularized summary in swedish) I den här avhandlingen har vi studerat bindväven i brosk. Bindväv är ett samlingsnamn för de stödjevävnader som ger form och struktur åt brosk, ben, senor, hud etc. Bindväven skyddar även inre organ från yttre påverkan. Det är bindväven som ger brosket dess speciella egenskaper och som gör att brosketThis thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. Here we show that chondroadherin also have a different exon-intron organization and chromosomal localiz