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In this work the syntheses, structure and SOD activity of covalently grafted Fe(III)-complexes formed with various N- or C-protected amino acid ligands (L-histidine and L-tyrosine) inspired by the active site of the Fe SOD enzyme are presented. Chloropropylated silica gel was used as support to mimic the proteomic skeleton of the enzyme. Anchored complexes having uniform amino acids as well as the

This paper reports results of a reexamination of some poorly understood peculiarities of laccases, an enzyme family which has been extensively studied in our laboratories as well as by others for some years. The issue that is reconsidered here is the previously proposed existence of ''active" and "resting" forms of laccases. The presence of fungal laccases with partly reduced active sites is demon

The present status of prompt particle emission from high-spin states in the mass A~60 region is shortly summarized. The focus lies on recent results from a GAMMASPHERE experiment, which aimed at the combined in-beam high-resolution spectroscopy of light charged particles and γ rays. More detailed studies of known cases as well as the identification of new cases of discrete prompt proton and α-part

Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. The main cause of death for women with breast cancer is secondary tumors. Downregulation of Wnt5a in primary ductal breast cancer has been correlated with poor outcome and higher tumor grade and found to be an independent predictor of recu

Based on sequence and phylogenetic analyses, glycoside hydrolase (GH) 3 can be divided into several clusters that differ in the length of their primary sequences. However, structural data on representatives of GH3 are still scarce, since only three of their structures are known and only one of them has been thoroughly characterized-that of an exohydrolase from barley. To allow a deeper structural

High-density lipoprotein (HDL) has anti-atherogenic properties and the plasma level of HDL cholesterol correlates inversely with the risk of coronary artery disease. The atheroprotective functions of HDL can be explained by its function in the reverse cholesterol transport. Blood coagulation is activated in response to tissue damage and involves a series of enzymatic protein complexes that assembl

Popular Abstract in Swedish Under sin livstid har Jorden genomlevt upprepade naturliga klimatförändringar. Genom att undersöka dessa klimatförändringar över tid och rum så kan vi öka vår förståelse för underliggande dynamik och mekanismer och därmed bättre förstå klimatsystemet. Två grundläggande förutsättningar för sådana undersökningar är trovärdiga rekonstruktioner av tidigare variationer i styThroughout its history Earth experienced a variety of natural climate changes. By investigating their spatial and temporal evolution we can increase the understanding of the mechanisms and dynamics underlying natural climate change and improve our general comprehension of the climate system. Prerequisites of these investigations are reliable reconstructions of past forcing variations as well as so

The present article discusses the Central Swedish word accents – Accent 1 and Accent 2 – and their productive association to suffixes from the point of view of prediction theories of speech processing. Based on recent neurophysiological findings, we propose that both word accents are used predictively, but that Accent 1 is more ‘predictively useful’ than Accent 2, due to the fact that Accent 1 ste

Popular Abstract in Swedish Målet avhandlingen har varit att undersöka möjligheten att bygga en kvantdator i kristaller dopade med joner av sällsynta jordartsmetaller. Det har visat sig att sådana joner har en väldigt lång livstid, vilket är en förutsättning för de typer av experiment som har utförts i den här avhandlingen. För att ytterliggare förhindra att de känsliga tillstånden i jonerna störs

We have carried out a combined X-ray photoelectron spectroscopy (XPS), ultraviolet photoelectron spectroscopy(UPS), and scanning tunnelling microscopy (STM) study of the C-60-Si(1 1 1) interaction where the XPS/UPS spectrometer and STM are integrated on a single UHV system. This enables a direct comparison of the XPS/UPS spectra with the STM data and eliminates any uncertainty in C-60 coverage mea

The centenary of the outbreak of the First World War in 1914 has spurred a lively popular and academic debate about the conflict's role in shaping the twentieth century and the European present. This article examines the war from a slightly different perspective, taking as its point of departure the impact of the war on neutral Scandinavia and its place in contemporary Scandinavian historical cons

Abstract Negative pressure wound therapy is a concept introduced initially to assist in the treatment of chronic open wounds. Recently, there has been growing interest in using the technique on closed incisions after surgery to prevent potentially severe surgical site infections and other wound complications in high-risk patients. Negative pressure wound therapy uses a negative pressure unit and s