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The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. Growing evidence indicates that patients with genetic susceptibilit
Popular Abstract in Swedish Alzheimers sjukdom (eng. Alzheimer’s disease, AD) är den vanligaste orsaken till de- mens. Demens innebär en permanent sänkning av intellektuella förmågor som påverkar individen påtagligt i vardagen. Förekomsten av demenssjukdomar ökar betydligt efter 65 års ålder. AD är en långsamt progredierande sjukdom, som oftast börjar med försämrat närminne. Redan idag är AD en beBackground: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. No diagnostic method can identify AD in patients with MC
Introduction: Older patients’ knowledge about their medicines is generally poor. Patients are entitled to be informed on an individual and adequate level. Evidence-based guidelines should, in most cases, be followed also in the treatment of elderly to avoid suboptimal treatment, for example for cardiovascular conditions, or risky prescriptions in the case of renal impairment. Objectives: 1. To de
Popular Abstract in Swedish Tuberkulos (tbc) är en av de sjukdomar som sedan tusentals år orsakat mest lidande för mänskligheten. Mycobacterium tuberculosis är den bakterie som orsakar tbc hos människor. Att vi lever tätare inpå varandra på grund av växande befolkning globalt gör att denna luftburna smitta kan fortleva. Fattigdom och undernäring är viktiga bidragande orsaker som förklarar varför dRapid, accurate diagnosis and management of TB in HIV-positive individuals is critical for the success of antiretroviral treatment programmes in primary health care in Sub-Saharan Africa. These studies aim to develop and evaluate methods for TB case finding in adults receiving care at Ethiopian health centres. The prevalence of active TB in a prospective cohort of 812 HIV-positive adults was deter
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Skivepitelcancer i huvud- och halsregionen (SCCHN) Kliniska aspekter Prognosen vid SCCHN är i stort sett oförändrat dålig sedan 30 år tillbaka; cirka hälften av patienterna dör av sin sjukdom. Trots stora tekniska framsteg kring behandlingsteknikerna (ofta en kombination av kirurgi, strål- och i viss mån cellgiftsbehandling) medför dAt present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. Tumor samples were investi
Popular Abstract in Swedish På utsidan av insidan - slemmet i tarmen Kroppens slemhinnor, till exempel de i magsäcken och tarmen, täcks av ett slemlager. Slemmet skyddar cellerna i slemhinnan från skadliga ämnen och mikroorganismer genom att ‘fånga’ dem och därmed hindra dem från att nå fram till cellerna. Slemmet är uppbyggt av stora, trådlika och ’klistriga’ molekyler, så kallade muciner, som gHighly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. Among the latter, the oligomeric mucins are responsible for mucus formation. The various tissues have characteristic muc
In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). Long-term growth factor-expanded
Popular Abstract in Swedish De flesta barn som insjuknar i epilepsi tillfrisknar eller blir anfallsfria med hjälp av antiepileptisk medicin. Hos drygt en fjärde del av barnen blir epilepsin svårbehandlad och anfallskontroll är svår att uppnå. Dessa barn ska i första hand erbjudas möjlighet till epilepsikirurgisk utredning och behandling. När epilepsikirurgisk behandling inte är möjlig att utföra eWhen anti-epileptic drugs fail, and epilepsy surgery is found unfeasible or ineffective, there remains a group of at least 25% of children with epilepsy in whom seizure control cannot be achieved. Vagus nerve stimulation (VNS) is an adjunctive treatment for medically refractory epilepsy. It is an implantable, multi-programmable pulse generator that delivers current electrical stimulation to the va
Många sjukdomar som inte beror på virus eller bakterier kopplas ofta till genetik. Vår förståelse kring hur gener påverkar vår hälsa har ökat dramatiskt med molekylärbiologins framfart. Sedan 1930-talet har det utvecklats nya tekniker för att tyda gener och dess DNA. Länge var gener ett ganska abstrakt koncept, man visste att det fanns något som fördes vidare genom generationerna men inte exakt vaTo find true genetic associations in complex diseases, such as allergic rhinitis and chronic rhinosinusitis, is a difficult task. Both are polygenetic diseases where it is believed that genetic variation in several genes make up their phenotypes. In addition, the environment of the affected individuals also play an important role, further obscuring eventual associations. Today most genetic associa
Ensamkommande unga som flyr undan krig eller förföljelse i sitt hemland möts i det nya landet av en migrationsprocess där åldern är central för prövningen av uppehållstillstånd. Anledningarna till det är flera. Bland annat tillerkänns personer under 18 år bostad, utbildning och sjukvård. Är den av sökanden påstådda åldern tveksam startar en åldersbedömning för att utreda om han eller hon är ett baUnaccompanied children who are fleeing war or persecution in their native country meet in the new country a migration process where the age is central for the legal examination of residence permit. The reasons for this are several. Among other things, individuals younger than eighteen are granted housing, education and medical care. If the age that the applicant claims is doubtful, an age assessme
Popular Abstract in Swedish Analytisk kemi är den gren inom kemin där man studerar, utvecklar och använder metoder och tekniker för att undersöka olika ämnens kemiska innehåll och exakta sammansättning. Den analytiska kemin spelar en mycket central roll inom många vitt skilda vetenskapliga fält och utgör den grund på vilka alla kemiska analyser vilar – medicinska tester och studier, kvalitetskontrFuelled by the current demands of the biological sciences, there is today a growing interest in microscale analysis. Miniaturisation of analytical instruments has become a long-standing trend. Miniaturisation offers several advantages, including rapid separation times, high performance and throughput, reduced costs, etc. But the increased surface area to volume ratio can sometimes be a disadvantag
Purpose: To evaluate and increase the efficiency of the internal processes by clearly visualizing the information flow and present improvement suggestions at Vestas Northern Europe.
Problem definition: To clearly define what information is shared today, identify where the critical interfaces take place and where vital information is lost.
Method: This study takes a her
1 Universitetsbiblioteket, Lunds universitet DE LA GARDIESKA ARKIVET TOPOGRAPHICA, Finland Förteckning reviderad av Per Stobaeus 2015 Inledning Handlingarna rörande Finland utgör en stor del av Topographica i De la Gardieska samlingen. Följande förteckning är en reviderad och utökad version av en äldre maskinskriven företeckning.1 Kapslarna 1 och 2 innehåller kronologiskt ordnade brev från 1300-ta
https://www.ub.lu.se/en/sites/ub.lu.se.en/files/forteckning_over_topographica_finland.pdf - 2026-07-13
COSM39 Documentary film in East and South-East Asia Course director Marina Svensson and other teachers include Chontida Auikool and Zeng Jinyan. The course is an elective 7,5 credit course within the Asian studies master programme, but it can also be read as a stand-alone course. The course focuses on the development of documentary film and the socio-economic and political context in which films a
https://www.ace.lu.se/sites/ace.lu.se/files/2021-06/COSM39_2021_Literature.pdf - 2026-07-13
LBIC maintains extensive collaborations at regional, national and international levels, which are essential for strengthening research infrastructure, advancing technological capabilities and maximizing scientific impact. These partnerships enable knowledge exchange, shared resources and coordinated development of advanced imaging methods across disciplines.Regional PartnershipsRegion SkåneAt the
https://www.lbic.lu.se/collaboration-partnership - 2026-07-11
With the increased occurrence of climate extremes, there is an urgent need to better understand how management strategies affect the capacity of the soil microbial community to maintain its ecosystem functions (e.g. nutrient cycling). To address this issue, intact monoliths were extracted from conventional and ecological managed grasslands in three countries across Europe and exposed under common
Neither true, nor useful The problem with framing climate change as a security threat Helena Gonzales Lindberg helenagonzaleslindberg@gmail.com 16 May 2011 Supervised by Turaj Faran turaj.faran@lucsus.lu.se A thesis submitted in fulfilment of the requirements of Lund University International Master’s Programme in Environmental Studies and Sustainability Science (LUMES) for the degree of Master of
https://www.lumes.lu.se/sites/lumes.lu.se/files/lindberg_helena_gonzales_thesis_2011_0.pdf - 2026-07-13
- when does what happen? The purpose of your time here at the Pufendorf IAS is to give you the space to explore the research problems which you described in your Theme or ASG application. As you know, we don’t expect deliverables, specific research output, but we do ask that you keep certain things in mind at specific times during your Pufendorf-year. AugustTheme: What day of the week would suit y
https://www.pi.lu.se/en/whats-going-pufendorf-ias/practical-information-themes-and-asgs/your-year-pufendorf-ias - 2026-07-11
Contributing to the Shaping of the Two UN Compacts on Refugees and Migration - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice
https://rwi.lu.se/contributing-shaping-two-un-compacts-refugees-migration/ - 2026-07-12
On this page you can read about the Faculty’s quality assurance work and about European, national and internal regulations, policies and recommendations that regulate higher education institutions and that are the starting point for the Faculty’s quality assurance processes in third cycle (doctoral level) education.The Faculty of Medicine is working systematically to maintain and develop quality i
