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Background/Purpose: There has been increasing interest in diet as a factor that may contribute to the development of rheumatoid arthritis (RA). There is limited and somewhat contradictory information on the impact of dairy products in this context. The purpose of this study was to investigate the relation between intake of various dairy products and the risk of RA in a nested case-control study.Me
Background: Homologous recombination (HR) deficiency (HRD) is prevalent in ovarian, prostate, and specific subgroups of breast cancer, particularly triple-negative breast cancer (TNBC). Tumor HRD status can be inferred through DNA-based, RNA-based, functional, or image-based approaches. A comprehensive evaluation of the concordance and discordance among HRD prediction methods derived from these di
This thesis consists of four empirical essays, all dealing with return volatility of financial assets and/or time-varying risk premia. In the first essay, Changing Risk Premia: Evidence from a Small Open Economy, the relation between risk and return is investigated for Swedish stocks. Little is known about the differences in the risk-return relationship in large economies compared with smaller, l
With today’s rapid changes in socio-economy and technology, knowledge and learning are critical issues for most companies and private and civil service organisations. The needs for competence development range from short informal courses to formal educational programs at university level. Informal learning is less predictable. It is nevertheless a very natural way of learning, although it is often
Aim: To assess the 2-year efficacy and tolerability of vildagliptin (50 mg once daily) in patients with type 2 diabetes (T2DM) and mild hyperglycaemia. Methods: This was a multicentre, randomized, double-blind, placebo-controlled trial comprising a 52-week core study with a 4-week, active treatment-free washout followed by a 52-week extension study with another washout period conducted in 131 drug
Negative pressure wound therapy in cardiac surgery Rainer Petzina, M.D. Clinical Sciences, Lund, Lund University Poststernotomy mediastinitis is a devastating complication for patients undergoing cardiac surgery. Conventional treatment includes surgical revision, continuous irrigation with drainage and wound closure with the use of the greater omentum and muscle flaps. Widespread adoption of ne
Background. Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing. Methods: We prospectively followed 478040 men and women from 10 European countries who were free of cancer at enrollment between 1992 and 1998. Information on diet and lifestyle w
Popular Abstract in Swedish Svensk Sammanfattning Gen-förändringar i endometrie- och ovarial cancer: Endometriecancer (EC, cancer i livmoderslemhinnan) är den vanligaste gynekologiska cancerformen i västvärlden. Tumörutvecklingen kan associeras till en östrogen-inducerad stimulans av endometriets tillväxt i avsaknad av den differentierande effekten av progesteron. Den maligna cancern föregås i visEndometrial cancer is the most common gynecological cancer diagnosed in western countries. Complex atypical hyperplasia (CAH) reflects a state of hyperestrinism and its role as a precursor lesion of this cancer is established. Endometrial cancers arising in association with CAH are reported in women of younger age, with early stage disease, favorable histological types, higher progesterone recepto
Bakgrund: För att tillverkande företag skall kunna vara konkurrenskraftiga, så är det viktigt att kontinuerligt sträva efter att eliminera alla orsaker till slöseri. En av de verktyg som kan användas för att bekämpa slöseri är TPM, vilket huvudsakligen är ett strukturerat sätt för att öka företagets tillförlitlighet till sina maskiner och produktionseffektiviteten genom att förstärka företagets unBackground: In order for manufacturing companies to stay competitive today, it is important to continuously strive towards eliminating any sources of waste. One of the tools to address waste elimination is to work with Total Productive Maintenance (TPM), which essentially is a structured way of improving the company’s machine reliability and production effectiveness through enhancing the sites mai
Relict spinel grains (similar to 25-250 mu m in diameter) from decomposed extraterrestrial material in Archean to Recent sediments can be used to reconstruct variations in the flux of different types of meteorites to Earth through the ages. Meteorite falls are rare and meteorites weather and decay rapidly on the Earth surface, making it a challenge to reconstruct ancient fluxes. Almost all meteori
Alla människor har rätt till hälsa enligt artikel 12 Konventionen om ekonomiska, sociala och kulturella rättigheter (ICESCR) och artikel 35 i EU:s rättighetsstadga (stadgan). För många människor är läkemedel livsviktiga. Emellertid har läkemedelsbolag med patenträttigheter en möjlighet till fri prissättning. Företag behöver tjäna pengar för att kunna forska fram nya produkter och läkemedelsbolag kAccess to pharmaceuticals can be vital for a lot of people. The public’s right to health is ensured by article 12 of the International Covenant on Economic, Social and Cultural Rights (ICESCR) and by article 35 of the Charter of Fundamental Rights of the European union (the EU Charter). However, pharmaceutical companies with patent rights can charge whatever price they want on medicines. Companies
In the last couple of decades in Sweden, there has been an adoption of “workfare”-oriented policy approaches to unemployment (as opposed to the former, less conditioned welfare-oriented ones). Consequently, labour market policies more and more have started to encompass the Social Services Department (in Swedish; “socialtjänsten”). In Scandinavia, active labour market policies are commonly referred
MAX-lab is a synchrotron radiation laboratory run in cooperation between Lund University and the Swedish Research Council. It currently consists of three stor-age rings, however, construction has begun of the fourth. MAX IV will be located outside of the Lund University Faculty of Engineering campus, in the northeastern part of Lund. Induced by the development in material technology at the nanomet
Runt om i världen pågår en omställning av energisystem på internationell, nationell och regional nivå av en omfattning som inte noterats på många årtionden. Omställningen innebär i första hand en övergång från fossila, icke förnybara energikällor till fossilfria, förnybara sådana med huvudsakligt syfte att begränsa de antropologiska klimatförändringarna och andra negativa effekter på miljön. Den f
Genom samhällsutvecklingen utmanas gamla sjukdomsbegrepp och lagar. I medierapportering och forskning har självskadebeteende uppmärksammats allt mer. Självskadebeteenden kan ta olika uttryck och även sex har påvisats kunna utgöra ett medel för att skada sig själv. Idag finns det medicinsk forskning om sex som självskadebeteende och rättsvetenskaplig forskning om tillämpningen respektive tolkningenSocietal development is constantly challenging old concepts of disease and law. In media reporting and medical research, self-injurious behavior has received increased interest. Self-injurious behavior can be expressed in various forms. Sex as self-injury is a new concept in the research field and the current knowledge of sex as self-injury did not exist when the Care of Young Persons Act, hereaft
I studien undersöks utmaningar och förbättringsförslag relaterade till arbetsmiljö, säkerhet och kommunikation inom byggindustrin för utländska arbetstagare, med extra fokus på länderna Polen och Litauen. Fri rörlighet för arbetstagare inom EU, som fastställs av artikel 45 i EUF-fördraget, möjliggör lika tillgång till både arbetsmöjligheter och behandling oavsett nationalitet. Syftet med studien The study examines challenges and improvement suggestions related to the work environment, safety, and communication within the construction industry for foreign workers, with a particular focus on Poland and Lithuania. The free movement of workers within the EU, as established by Article 45 of the treaty on the functioning of the European Union, ensures equal access to both employment opportuniti
Interactions between metals and natural organic matter (NOM) are of great environmental importance and one of the key factors influencing hydrolysis, solubility, and speciation of the metals. However, studying geochemically relevant metals like Al, Fe, and Cu is sometimes associated with analytical problems; for example Fe and Cu are both redox active. Gallium (Ga) is a non-redox active metal that
In 1997-2003, a protocol for treatment of acute myeloid leukaemia (AML) (except promyelocytic leukaemia) was activated in four Swedish health care regions covering 50% of the national population. Based on cytogenetics and clinical findings, patients aged 18-60 yr were assigned to one of three risk groups. In this report we account for the long-term clinical outcome of enrolled patients. Patients r
NMR relaxation experiments have provided a wealth of information about molecular motions in macromolecules and ordered fluids. Even though a rigorous theory of spin relaxation is available, the complexity of the investigated systems often makes the interpretation of limited datasets challenging and ambiguous. To allow physically meaningful information to be extracted from the data without commitme
In the future atmospheric CO2 concentrations might exceed 550 ppm according to the RCP8.5 scenario by mid-century from our current 410 ppm, while our world population is projected to surpass the 9.7 billion threshold within the same time span. This challenge leads to the raising of questions addressing future food security. Elevated CO2 has been shown to not only increase photosynthetic rates in
