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Background: Weused a sensitive and specific beta-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) assay to determine the relationship between BACE1 activity in cerebrospinal fluid (CSF) and markers of APP metabolism and axonal degeneration in early and late stages of Alzheimer disease (AD). Objective: To assess CSF BACE1 activity in AD. Design: Case-control and longitudinal follow-up
Popular Abstract in Swedish Leukemi, "det vita blodet", var ursprungligen en beskrivande diagnos på tillstånd där leukocyter (vita blodkroppar), eller snarare deras maligna, d.v.s. canceromvandlade former, tillväxte i sådan grad att de trängde undan andra blodbildande celler. I en sådan situation drabbas patienterna av blodbrist, infektioner och blödningar. Med tiden har vi lärt oss särskilja olikIn the present thesis, clinicogenetic correlations are investigated in a large population-based series of acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), acute lymphoblastic leukemia, and chronic myeloid leukemia, for which the karyotypes were analyzed at the same center. The karyotypic pattern, i.e. normal karyotype or 1, 2 or ³3 anomalies, does not differ between males and female
Popular Abstract in English Typically, when we speak of ionic solutions we mean a salt (as solute) dissolved in some liquid (the solvent). In this thesis, we predominantly consider ionic solutions for which there is no solvent---room-temperature ionic liquids (RTILs). It follows that these liquids have a large concentration of charged particles, a property that causes them to be effective electrRoom-temperature ionic liquids (RTILs) are compounds composed entirely of ions, which are liquid at temperatures below 100 degrees Celsius. Their high ionic strength and strong coupling make them useful for a number of applications, e.g. as electrolytes in supercapacitors. These properties also make them interesting subjects for theoretical research, as the canonical theories of the electrical dou
Long-term eddy covariance measurements of energy and water fluxes and associated climatic parameters were carried out above a Scots pine (Pinus sylvestris) forest in the middle taiga zone of Central Siberia. Data from June 1998 through October 2000 are presented. With the exception of winter 1998/1999, data collection over this period were more or less continuous. A distinct seasonality in surface
Inland waters were recently recognized to be important sources of methane (CH4 ) and carbon dioxide (CO2 ) to the atmosphere, and including inland water emissions in large scale greenhouse gas (GHG) budgets may potentially offset the estimated carbon sink in many areas. However, the lack of GHG flux measurements and well-defined inland water areas for extrapolation, make the magnitude of the poten
Popular Abstract in Swedish Östersjön är ett grundhav med tillförsel av saltvatten från havet och sötvatten från omgivande floder. De två vattenmassorna är vertikalt skiktade, vilket resulterar i en estuarin cirkulation, vilken har genomgått stora förändringar till följd av landhöjningen efter senaste nedisningen. För att kunna rekonstruera havsmiljöers förändringar bakåt i tiden är det nödvändigtThe Baltic Sea is a continental shelf sea that is influenced by both river runoff and marine water. The two water masses are vertically stratified in the Baltic Sea, resulting in a positive, estuarine circulation system, which has undergone changes in the past due to isostatic uplift of the Baltic basin. For researchers to understand past changes in the marine environment of the Baltic Sea, a soun
Popular Abstract in Swedish Akupunktur är en mer än 2000 år gammal terapeutisk metod, som ingår i den traditionella kinesiska medicinen (TCM), för lindring av en del sjukdomar och symtom såsom smärta. Tunna, solida nålar instickes i så kallade akupunkturpunkter, oftast belägna i muskulaturen och utspridda över hela kroppen längs linjer som kallas meridianer. Det finns ett flertal olika sätt att teIn a retrospective follow-up study, n=202, long-term pain relief (>6 months) after a course of acupuncture treatments was found mainly among patients with chronic nociceptive pain while patients with neurogenic or psychogenic pain did not benefit much. In a placebo-controlled randomised single-blind long-term study with independent observer of chronic nociceptive low back pain, n=50, it was found
Popular Abstract in Swedish Ett fonetogram är ett diagram som beskriver röstfunktionens status genom att visa extremvärden av ljudtrycksnivå som funktion av grundtonsfrekvens. Tillvägagångssättet är att försökspersonen uttalar en vokal, i denna avhandling genomgående vokalen [a], på en given tonhöjd så svagt och så starkt som möjligt inom hela röstomfånget. Provet utföres i ett ljudisolerat rum meA phonetogram is a diagram displaying sound pressure levels (SPL) of softest and loudest possible phonation over the entire fundamental frequency range (F0) of a voice. Female singers mean phonetogram had a significantly higher upper contour than female nonsingers. When reading at various voice levels female singers produced markedly higher mean equivalent sound pressure levels (Leq) and mean rel
Popular Abstract in English Plants harvest sunlight to fix air carbon dioxide into a form which is the fundamental source of energy for other organisms such as animals. The domestication of crop plants and traditional breeding practices has resulted in increased yield and nutritional value of crops. This comes at a cost of loss in genetic variability that is required by living organisms to adapt tPotato is one of the major food crops and its yield is severely affected by late blight disease caused by Phytophthora infestans. P. infestans has the ability to manipulate plant defence signalling by secreting effector molecules causing so called effector triggered susceptibility. Some plants can recognize these effectors via resistance proteins that reactivate plant defence and lead to effector
Bygg- och fastighetssektorn står inför en stor förändringsprocess för att kunna minska sin miljö- och klimatpåverkan. Ur ett europeiskt perspektiv står byggsektorn idag för hälften av alla råvaror som utvinns, hälften av den totala energianvändningen, en tredjedel av all vattenanvändning och en tredjedel av allt avfall som genereras. Genom att skapa en mer cirkulär byggbransch minskar klimatutsläp
A recent statement from the European-Society-for-Sexual-Medicine has highlighted the limitations of using the rat model for nerve-sparing prostatectomy. The use of young rats with no comorbidities and the early evaluation of the erectile function (EF) are deemed a source of bias. Our aim was to evaluate the long-term consequences in EF of bilateral nerve cavernous crush- injury (BNCI) in type 1 di
Den 1 januari 2016 skärptes kraven för luftutsläpp från förbränningsanläggningar genom För-ordningen (2013:252) om stora förbränningsanläggningar. I förordningen skärptes bland annat kraven för utsläpp av kväveoxider, NOX. Till följd av de skärpta kraven berördes Kraftringens produktionsanläggning Gunnesboverket. På anläggningen finns tre biooljeeldade hetvatten-pannor för fjärrvärmeproduktion därNew regulations regarding emissions of air pollutants came into force as of January 1st 2016 in Sweden. The regulations are found in “The Regulation on Large Combustion Plants” SFS 2013:252. The regulation contained stricter regulations of NOX emissions which affected the energy company Kraftringen and their three biooil-fueled boilers, at the heating plant Gunnesboverket, that are used for produc
Individuals with chronic lymphocytic leukemia (CLL) face an increased risk for severe COVID-19. This study from Sweden, a country that only had a few mandatory restrictions at the onset of the pandemic, used 10 nationwide registers to compare the risks for severe COVID-19 outcomes of polymerase chain reaction-verified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections through
Purpose: The purpose of this research was to investigate how outdoor textile brands align their brand bdentity with their management actions and communication to become more circular. It was as a consequence explored how communication strategies of outdoor brands align with their management decision and how management actions push the transition of a brand towards more circularity. Methodology: Th
Titel: Att träna eller inte träna - en enkätstudie över en grupp kvinnors träningsvanor och besvär före och under graviditet Bakgrund: Under en graviditet drabbas många kvinnor av olika besvär och komplikationer, exempelvis ländryggs- och bäckensmärta, graviditetsdiabetes, illamående och havandeskapsförgiftning. Genom träning kan man minska risken för att utveckla dessa besvär men även uppnå flera
This paper investigates the accuracy of three different methods that are used to perform a relative valuation. I also study the valuation accuracy of the three most widely used multiples used within these methods, the enterprise value to EBITDA (EV/EBITDA), the forward-looking price per share to earnings per share (P/EPS1), and the price-book (P/B). In addition, the difference between industries r
Studien syftar till att ta fram rekommendationer och råd kring hur klimatpåverkan från anläggningsentreprenader kan beräknas och redovisas. Detta genom att undersöka hur andra aktörer inom branschen agerar i frågan och kartlägga modeller och verktyg för klimatberäkningar. Studien har utförts som en kombination av kvalitativa och kvantitativa forskningsmetoder, vilket kan liknas vid begreppet triaThe purpose of the study is to come up with recommendations and advice on how to calculate and present the climate impact from construction works. This will be implemented by examining how other actors within the construction industry is acting on the issue and examine models and tools for climate calculations. The study was conducted as a combination of qualitative and quantitative research meth
This study assesses the performance of buildings affected by climate change under future climate predictions for three time-periods until the end of the 21st century. Objects studied are residential multi-storey buildings, originally built before 1970 and retrofitted during the last decade. A total of four actual retrofit projects, as they were performed, in Denmark and Germany were assessed in th
Abstract Title: Market Reactions to Dividend Announcements: Evidence from the Swedish Stock Market Seminar Date: 31 May 2024 Course: FEKH89, Degree Project Undergraduate level, Business Administration, 15 ECTS Authors: Suprit Chowdary, Edgar Fahlström Nygren, Jacob Rothstein Advisor: Anamaria Cociorva Keywords: Dividend Announcements, Dividend Changes, Consensus Estimates, Cumulative Abnorma
European Spallation Source (ESS) är en partikelaccelerator under konstruktion i Lund. Den kommer att skjuta protoner mot ett stort “hjul” av Wolfram, för att skapa neutroner till forskning. Hjulet kommer efter användning att bli mycket radioaktivt. En olycka, såsom att kylningssystemet går sönder, skulle släppa ut radioaktivt material som kan spridas med vinden och potentiellt bli en hälsorisk förA gamma-charged particle coincidence spectroscopy setup was constructed, with the intended purpose of analysing future aerosol samples from the ESS. The setup consists of a Compex composite high purity germanium (HPGe) detector, with a bismuth-germanate oxide (BGO) anti-Compton shield (ACS), and a single-sided silicon strip detector (SSD). A 207Bi sample was used to evaluate the performance of the
