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The association between medical risk factors and the outcome of foot ulcers was evaluated in 208 consecutive diabetic patients with severe peripheral vascular disease (systolic toe blood pressure < or = 45 mm Hg). All patients were treated and followed by the same foot care team. Eighty patients healed primarily, 83 healed after a minor or major amputation, and 45 died. The systolic toe blood pres

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PURPOSE: We review the current epidemiological and genetic knowledge regarding hereditary prostate cancer, and outline its clinical implications. MATERIALS AND METHODS: Published articles on hereditary prostate cancer were identified using the MEDLINE data base. RESULTS: A risk of prostate cancer, particularly early onset disease, is strongly affected by family history (number of relatives with pr

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Background: Limited information exists on the framework and content of postgraduate education in internal medicine in Europe. This report describes the results of a survey of postgraduate training in internal medicine in the European countries. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the othe

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Adult neurons possess the ability to adapt to a changing environment. Loss of target-derived neurotrophic factors due to axotomy or isolation by culturing is known to induce changes in neuropeptide expression in several types of peripheral neurons. The aim of the present study was to investigate changes in the expression of vasoactive intestinal polypeptide (VIP) and nitric oxide synthase (NOS) in

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Context: When using the Case Method in teaching situations, problem-solving is emphasized and taught, in order to acquire the skills and later be able to apply them in new situations. The basis of the learning process is the students’ own activity in the situation and is built on critical appraisal and discussion. Objectives: To explain what the Case Method is, what it is not and to describe when

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In recent years, public as well as private measures taken in order to protect the environment have proved to affect competition. As consumers have become more and more alert to the environmental effects of the manufacture, use and ultimate disposal of goods, undertakings have taken measures improving the environmental protection not only due to legislation imposing stricter standards on products a

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Sammanfattning Den kanske största miljöpolitiska utmaningen inom Europa är för närvarande frågan om hur det är möjligt att på ett effektivt och ändamålsenligt sätt uppnå miljömålen i syfte att skapa en hållbar utveckling i samhället. Trenden har gått från att tillgripa lagstiftningsåtgärder till att via marknadsbaserade styrmedel försöka involvera olika marknadsaktörer att på egen hand bli delaktSummary Potentially one of the greatest environmental policy challenges in the European Union is the question of how to efficiently and effectively achieve environmental goals through which society can correct for and obtain a level of sustainable development. The trend has gone from one of command and control legislation towards using more market-based instruments that seek to involve the differ

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During the last few years, crowding effects on the physics of proteins has become an increasingly popular topic of research. This is is because most biological processes involving proteins naturally take place in a crowded environment, e.g. in the cellular environment where macromolecules may occupy 30% of the volume. One such biological process would be the formation of amyloid aggregates, which

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The present Comite´ Europe´en de Normalisation (CEN) and International Organization for Standardization (ISO) standards for safety, protective and occupational footwear EN ISO 20344–20347 classify footwear as cold protective by a pass/fail test where the limits are set for an allowed 10 °C temperature drop inside the footwear during 30 min at a temperature gradient of ~40 °C. It is questionable if

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Laminar burning velocities of syngas/air premixed flames, varying with H-2/CO ratio (from 5/95 to 75/25) and N-2 or CO2 dilution rate (from 0% to 60%), were accurately measured using a Teflon coated Heat Flux burner and OH-PLIF based Bunsen flame method. Experiments were carried out at atmospheric pressure and room temperature, with fuel/air equivalence ratios ranging from fuel-lean to fuel-rich.

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Alpha-1-antitrypsin (AAT) is a glycoprotein synthesised in the liver. Its main role is to protect lung tissue from destruction by neutrophil elastase. In severe (PiZZ) AAT deficiency, there is an increased risk of emphysema, especially in smokers. The deficiency is caused by the retention and aggregation by polymerization of the AAT molecules in the liver, which increases the risk of neonatal chol

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Background: The link between squamous cell cervical carcinoma and human papillomavirus (HPV) 16/18 is well established, but the magnitude of the risk association is uncertain and the importance of other high-risk HPV (HRHPV) types is unclear. Methods: In two prospective nested case-control series among women participating in cytologic screening in Sweden, we collected 2,772 cervical smears from 51

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Background: Optimal manual closed chest compressions are difficult to give. A mechanical compression/ decompression device, named LUCAS, is programmed to give compression according to the latest international guidelines (2005) for cardiopulmonary resuscitation (CPR). The aim of the present study was to compare manual CPR with LUCAS-CPR. Methods: 30 kg pigs were anesthetized and intubated. After a

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This essay focuses on experiences of sexual harassment / abuse taken from www.minnen.se which tellstheir stories in a narrative form. The experiences shared via minnen.se are largely positive. The focus is circuit on upset feelings and displeasure of a more or less social accepted behavior, and lack of trust in the legal system. To handle the material, a criminological and sociological perspective

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Interneurons have been found to be important for normal cognitive function. Impairments to their growth or signaling have been indicated to be involved in the development of schizophrenia, autism and epilepsy. Defective functioning in GABA:ergic interneurons has been linked to undesired desynchronous firing in neural signals as a consequence of these interneurons firing too infrequently or not at

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In China, the past 30 years have been characterized by economic growth and rapid development that has transformed the nation into an important player on the international market. This phenomenal progress probably would have been impossible without the cheap labor force provided by the Chinese countryside in the form of migrant workers. Millions of rural people circulate the nation today in order t

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Infant mortality is a powerful indicator to measure the health and social status of a country. The purpose of this study is to identify the important factors that in uence the infant mortality of Bangladesh. Moreover, this study suggests the government and the policy makers to improve the health and social sectors for reducing the country's infant mortality signicantly. To investigate the impo