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Objectives: Irreversible electroporation (IRE) is a new modality for tumor ablation. Electrodes are placed around the tumor, and a pulsed, direct current with a field strength of 2000 V/cm is delivered. The direct current drives cells into apoptosis and cell death without causing significant heating of the tissues, which spares the extracellular matrix and proteins. The purpose of this review was
Overweight and obesity are increasing worldwide, but the extent in breast cancer patients is unknown. The two aims were to study secular trends in preoperative body mass index (BMI), waist circumference, and breast volume and their impacts on clinical outcome. BMI, waist circumference, and breast volume were measured preoperatively in 24–99-year-old primary breast cancer patients (n = 640) in Swed
Alloimmunization against the RhD antigen is the most common cause of hemolytic disease of the fetus and newborn. Antenatal anti-D prophylaxis in addition to postnatal anti-D prophylaxis reduces the number of RhD-immunizations compared to only postnatal administration. Cell-free fetal DNA released from the apoptotic trophoblastic placental cells into the maternal circulation can be used to determin
Although a number of different medium access control (MAC) schemes are adopted for wireless multi-hop networks, time division multiple access (TDMA) approaches based on a periodic frame of time slots are the most common when very high efficiency is needed in terms of use of radio and energy resources. Efficient resource usage is typically based on parallel compatible transmissions from multiple no
Effective societal responses to rapid climate change in the Arctic rely on an accurate representation of region-specific ecosystem properties and processes. However, this is limited by the scarcity and patchy distribution of field measurements. Here, we use a comprehensive, geo-referenced database of primary field measurements in 1,840 published studies across the Arctic to identify statistically
The recent more or less complete return and recovery in Skåne, southern-most Sweden, of epiphytic bryophyes known to have suffered from atmospheric pollution in the mid 1900’s, e.g. Zygodon rupestris, Antitrichia curtipendula, Leucodon sciuroides, Orthotrichum lyellii, O. speciosum and O. stramineum, is here discussed and illustrated on maps. However, apart from these successful recoveries, at lea
I detta delprojekt har följande genomförts:• Beräkning av effekterna av solinstrålning och förvärmning av luften vid inglasning av befintliga byggnader• Beräkning av energibesparing vid inglasning• Beräkning av termisk komfort och studie av effektiva passiva kylåtgärder• Framtagande av datorverktyg (modeller och moduler för energiberäkningsprogram, Glazing-LTH) för att bättre kunna uppskatta effek
OBJECTIVE: The midwife assisting a birth has a considerable influence on the woman's experience of the birth. The aim of this study was to investigate the experience of the midwife's professional skills among women in Norway, Denmark, Iceland, and Sweden who chose a planned home birth.DESIGN AND SETTING: All known home birth midwives were asked to inform the mothers about the project and invite th
Introduction: Soft tissue knee injury is a well-established and potent risk factor for development of knee osteoarthritis. However, there is a paucity of epidemiological data from the general population. Our aim was to estimate the annual person-level incidence for a wide spectrum of clinically diagnosed soft tissue knee injuries, and their distribution by age, sex, and season. Methods: In Sweden,
Some large ecological studies have noted a significant association of testicular cancer (TC) with maternal smoking during pregnancy, while several more controlled studies have been negative. It has been difficult to obtain reliable data on exposure because of the long lag time to cancer diagnosis. We performed a case-control study nested within Finnish, Swedish and Icelandic maternity cohorts expl
In order to obtain information on genes specifically expressed in the ectomycorrhizal symbiosis, 3,555 expressed sequence tags (ESTs) were analyzed from a cDNA library constructed from ectomycorrhiza formed between the basidiomycete Paxillus involutus and birch (Betula pendula). cDNA libraries from saprophytically growing fungus (3,964 ESTs) and from axenic plants (2,532 ESTs) were analyzed in par
Popular Abstract in Swedish Frågan om marknadshandelns karaktär har aktualiserats genom de skandaler inom företagsvärlden som media har lyft fram under senare år. Dagens situation väcker frågor om den handel som förekom i äldre samhällen? Existerade marknadshandel till exempel under vikingatid? Om så var fallet hur uppfattades och hanterades marknadshandel i detta samhälle? Handelns roll för det The view of the exchange and trade that took place during the Viking Age has varied considerably. This variation is obvious from a scrutiny of how one and the same place, Birka, is described by different scholars over a period of a hundred years. Two very polarized pictures of Birka appear: A town with a mostly free market-oriented trade or an emporium with an administered commodity exchange contr
In this thesis, theoretical models are applied to study some aspects of intrinsically disordered proteins, i.e. proteins that partly or entirely lack a stable native structure. In particular, focus is on peptide binding and aggregation. Knowledge about these mechanisms is important for understanding how proteins interact with each other and how mutations can affect the function and sometimes give
The fire technical properties of products are determining factors for the initiation and growth of fires. Measurement of fire technical properties and the understanding of how they relate to real hazards are therefore important for fire safety. This work deals with the fire technical properties of building products, their tendency to ignite and release heat in different fire scenarios. Building p
OBJECTIVE:: Emerging evidence suggests that women with vasomotor menopausal symptoms (VMS) may have an adverse cardiovascular disease (CVD) risk profile. We investigated whether VMS are related to an increased risk of future coronary heart disease (CHD) and whether possible associations can be explained by CVD risk factors. METHODS:: Data used were from a Dutch and Swedish population-based sample
AIMS/HYPOTHESIS: Islet autoantibodies are important in diabetes classification and risk assessment, and as endpoints in observational studies. The Diabetes Autoantibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type 1 diabetes. We report results for glutamic acid decarboxylase autoantibodies (GADA) and islet antigen-2 autoantibodie
PURPOSE To evaluate the early treatment response in children with acute myeloid leukemia (AML) using a response-guided induction strategy that includes idarubicin in the first course. PATIENTS AND METHODS All Nordic children with AML younger than 15 years (n = 151) were treated on the Nordic Society for Pediatric Hematology and Oncology (NOPHO) AML 2004 protocol. After the first course of idarubic
Both the external oxidation of NADH and NADPH in intact potato (Solanum tuberosum L. cv. Bintje) tuber mitochondria and the rotenone-insensitive internal oxidation of NADPH by inside-out submitochondrial particles were dependent on Ca2+. The stimulation was not due to increased permeability of the inner mitochondrial membrane. Neither the membrane potential nor the latencies of NAD+-dependent and
