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Objectives: Irreversible electroporation (IRE) is a new modality for tumor ablation. Electrodes are placed around the tumor, and a pulsed, direct current with a field strength of 2000 V/cm is delivered. The direct current drives cells into apoptosis and cell death without causing significant heating of the tissues, which spares the extracellular matrix and proteins. The purpose of this review was
Introduction: Given considerable focus on health outcomes among childhood cancer survivors, we aimed to explore whether survivor bias is apparent during long-term follow-up of childhood cancer survivors. Methods: We identified all 1-year survivors of cancer diagnosed before 20 years of age in Denmark, Finland, Iceland, and Sweden. From the general population, we randomly sampled a comparison cohor
We present extensive density-functional theory (DFT) based calculations of the clean Rh(111) surface and of CO/Rh(111) overlayer systems. We study both ground-state structural properties and core-level shifts from differences in total energies at different coverages and adsorption sites. Most results are obtained using using norm-conserving or ultrasoft pseudopotentials. The overall reliability of
Postal address P.O. Box 117, SE-221 00 Lund Visiting address Sandgatan 13A, building Gamla Kirurgen Telephone +46 46 222 00 00 Website www.sam.lu.se/en Reading list SGR016F, Sustainability Science and the SDGs: Foundations, concepts, methodologies, 7.5 credits, third cycle The reading list was approved by the Research Studies Council 4 November 2020 and is valid from the spring semester 2021. Theo
The darknet cryptomarkets marked an evolution in the drug trade by providing technological anonymity and security for both sellers and buyers. Together with their surrounding forums, they form an ecosystem where participation and access to its safety and harm reduction benefits depend on digital capital, a resource that is not equally available to all. This study examines how digital capital influ
Microsoft Word - Lägesrapport från projektet ”Minnet är kort – lantbrukares upplevelser av torkan 2018”, 19-11-19.docx Lägesrapport från projektet ”Minnet är kort – lantbrukares upplevelser av torkan 2018” Lunds universitet, november 2019 Bakgrund Projektet ”Minnet är kort – lantbrukares upplevelser av torkan 2018”, finansierat av forskningsrådet Formas med så kallat ”akutbidrag” går in i sitt slu
Guidelines for Research and Innovation Projects in the European Union's Framework Programme Horizon Europe REGULATORY DOCUMENT COVER PAGE Guidelines for Research and Innovation Projects in the European Union’s Framework Programme Horizon Europe (2021-2027) Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in t
OBJECTIVE: The late revelation of ovarian cancer ensures it as the leading cause of death among gynecologic cancers. Cytoreductive surgery (CRS) and intravenous (i.v.) chemotherapy have been the cornerstone for a long time to treat this disease. More recently, the modality of intraperitoneal administration of chemotherapy under hyperthermic conditions (HIPEC) has been added. This review surveys th
The circulation is a closed system that has been assumed to be free from bacteria, but evidence for the existence of a low-density blood microbiota is accumulating. The present study aimed to map the blood microbiota of outpatients with Crohn’s disease (CD) or with ulcerative colitis (UC) by 16S metagenomics. A diverse microbiota was observed in the blood samples. Regardless of the type of disease
A novel energy management (EM) approach is introduced, integrating core elements of collective intelligence (CI) and reinforcement learning (RL) and called CIRLEM. It operates by distributing a flexibility signal from the energy supplier to agents within the grid, prompting their responsive actions. The flexibility signal reflects upon the collective behaviour of the agents in the grid and agents
Efficient and timely maintenance is essential for the robust operation of infrastructure across all types of transport. In the railway sector, track maintenance presents unique challenges. Specifically, some maintenance tasks require track closures, which can disrupt train schedules. Coordinating these closures with regular train operations makes the scheduling process complicated. To ensure suffi
In the CONVINCE trial, the primary analysis demonstrated a survival benefit for patients receiving high-dose hemodiafiltration (HDF) as compared with high-flux hemodialysis (HD). A secondary objective was to evaluate effects on health-related quality of life (HRQoL); assessed in eight domains (physical function, cognitive function, fatigue, sleep disturbance, anxiety, depression, pain interference
Light-chain (LC) monoclonal gammopathy of undetermined significance (MGUS) is a precursor of multiple myeloma (MM) and related conditions. LC-MGUS is characterized by free light-chain (FLC) levels outside defined reference intervals, indirectly indicating underlying plasma cell (PC) monoclonality. Next-generation flow cytometry (NGF) was used to evaluate clonal PC presence in bone marrow (BM) samp
Severe viral pneumonia is a significant cause of morbidity and mortality globally, whether due to outbreaks of endemic viruses, periodic viral epidemics, or the rarer but devastating global viral pandemics. While limited anti-viral therapies exist, there is a paucity of direct therapies to directly attenuate viral pneumonia-induced lung injury, and management therefore remains largely supportive.
Popular Abstract in Swedish Frågan om marknadshandelns karaktär har aktualiserats genom de skandaler inom företagsvärlden som media har lyft fram under senare år. Dagens situation väcker frågor om den handel som förekom i äldre samhällen? Existerade marknadshandel till exempel under vikingatid? Om så var fallet hur uppfattades och hanterades marknadshandel i detta samhälle? Handelns roll för det The view of the exchange and trade that took place during the Viking Age has varied considerably. This variation is obvious from a scrutiny of how one and the same place, Birka, is described by different scholars over a period of a hundred years. Two very polarized pictures of Birka appear: A town with a mostly free market-oriented trade or an emporium with an administered commodity exchange contr
We investigated the class II B genes in a free-ranging population of the ring-necked pheasant Phasianus colchicus by a combination of restriction fragment length polymorphism (RFLP), polymerase chain reaction (PCR), and DNA sequencing. Special attention was paid to the variation in the second exon, which encodes the peptide-binding beta(i)-domain. The population was introduced, but it still exhibi
OBJECTIVE:: Emerging evidence suggests that women with vasomotor menopausal symptoms (VMS) may have an adverse cardiovascular disease (CVD) risk profile. We investigated whether VMS are related to an increased risk of future coronary heart disease (CHD) and whether possible associations can be explained by CVD risk factors. METHODS:: Data used were from a Dutch and Swedish population-based sample
PURPOSE To evaluate the early treatment response in children with acute myeloid leukemia (AML) using a response-guided induction strategy that includes idarubicin in the first course. PATIENTS AND METHODS All Nordic children with AML younger than 15 years (n = 151) were treated on the Nordic Society for Pediatric Hematology and Oncology (NOPHO) AML 2004 protocol. After the first course of idarubic
Aqueous dispersions of charged-neutral block copolymers (poly(acrylamide)-b-poly(acrylate)) complexed with an oppositely charged surfactant (dodecyltrimethylammonium) have been prepared by different approaches: the simple mixing of two solutions (MS approach) containing the block copolymer and surfactant, with their respective simple counterions, and dispersion of a freeze-dried complex salt prepa
