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BACKGROUND: Genetic variants in KLK2 and KLK3 have been associated with increased serum concentrations of their encoded proteins, human kallikrein-related peptidase 2 (hK2) and prostate-specific antigen (PSA), and with prostate cancer in older men. Low PSA concentrations in seminal plasma (SP) have been associated with low sperm motility. To evaluate whether KLK2 and KLK3 genetic variants affect p

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Vitellogenin (VTG) is a well known protein biomarker for exposure to environmental estrogens and possible endocrine disruption in fish. VTG is very dominant in plasma after the onset of vitellogenesis and the protein is heavily phosphorylated. This enables indirect quantification through measurement of alkali-labile protein bound phosphate (ALP) as an alternative to the more expensive enzyme linke

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Popular Abstract in Swedish Shimazaki Toson (1872 - 1943) anses vara Japans främste företrädare för shizenshugi - en japansk form av fransk Naturalisme. Hans debut som romanförfattare skedde 1906 med Hakai - Löftesbrottet. Romanen anses allmänt vara en representant för kokuhaku shosetsu, eller en "bekännelseroman". Denna avhandling påvisar att författaren hade politiska ambitioner att påvisa diskrPublished in 1906, Hakai or The Broken Commandment in English, by Shimazaki Tôson, is generally considered the first novel in the genre of shizenshugi, a Japanese variation of French Naturalisme. Traditionally, the novel has been viewed as an example of kokuhaku shôsetsu, or “confessional novel” in that the protagonist “confesses” his origin as a member of Eta¾an autochtonous and despised minority

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In this article, we revisit a classical optimization problem occurring in designing survivable multicommodity flow networks. The problem, referred to as FR, assumes flow restoration that takes advantage of the so-called stub release. As no compact linear programming (LP) formulation of FR is known and at the same time all known noncompact LP formulations of FR exhibit NP-hard dual separation, the

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Oatly is a company that produces and sells oat based products. Their most selling product is the oat drink, which is a substitute to milk, and over 80 percent of the annual sales volume comes from this product. Since the foundation of Oatly, the main idea has been to sell their products on markets with low milk availability and milk consumption. Most recently, Oatly identified the Chinese market a

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Populärvetenskaplig sammanfattning: Examensarbetet har gått ut på att med hjälp av satellitbilder göra markanvändningsdata för att förbättra en modell som beräknar vart de luftburna föroreningarna tar vägen. Föroreningarna svavel och kväve deponeras med olika hastighet över olika marktyper, därför vill man använda sig av markanvändningsdata i modellerna. Svavelutsläppen har ökat dramatiskt under Sulphur emissions during the last century has led to major acidification of the environment. The acidity of soil and water is a threat to health and economic interests of man, e.g. the food and paper/wood production in the agricultural and silvicultural industries. The Black Triangle region suffers from severe damage caused by acidification and actions to decrease the acid rain over fields and for

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The purposes of this article-based thesis are to explore and understand preaching as a practice in general, and the practice of preaching in digital culture and spaces in particular. Informed by the practice theory of Theodore Schatzki, it presents the results of a cross-case analysis of four different case studies of the practice of preaching in digital culture and spaces in Swedish protestant chThe purposes of this article-based thesis are to explore and understand preaching as a practice in general, and the practice of preaching in digital culture and spaces in particular. Informed by the practice theory of Theodore Schatzki, it presents the results of a cross-case analysis of four different case studiesof the practice of preaching in digital culture and spaces in Swedish protestant chu

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This article aims to ‘dig for the roots’ of the entanglement between secularity and the Bible in Sweden. By employing the concepts “religionization” and “biblical assemblages,” this study identifies and analyzes the interplay between perceptions of secularity and the Bible in the public debate on women’s ordination in the Church of Sweden (CofS) in the 1950s – a crucial decade in the secularizatioThis article aims to ‘dig for the roots’ of the entanglement between secularity and the Bible in Sweden. By employing the concepts “religionization” and “biblical assemblages,” this study identifies and analyzes the interplay between perceptions of secularity and the Bible in the public debate on women’s ordination in the Church of Sweden (CofS) in the 1950s – a crucial decade in the secularizatio

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This workshop presents an interactive and participant-oriented form of poetic inquiry that invites active and collaborative exploration of student voices through artistic, hands-on engagement.By combining ideas from concrete and graphic poetry – such as those of the pioneering poet and theorist Mary Ellen Solt – with principles of arts-based and participatory research, the session introduces a metThis workshop presents an interactive and participant-oriented form of poetic inquiry that invites active and collaborative exploration of student voices through artistic, hands-on engagement. By combining ideas from concrete and graphic poetry – such as those of the pioneering poet and theorist Mary Ellen Solt – with principles of arts-based and participatory research, the session introduces a me

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Massively multidimensional diffusion-relaxation correlation MRI provides detailed information on tissue microstructure by analyzing water populations at a sub-voxel level. This method correlates frequency-dependent tensor-valued diffusion MRI with longitudinal and transverse relaxation rates, generating non-parametric D(ω)-R1-R2-distributions. Traditionally, D(ω)-R1-R2-distributions are separated

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INTRODUCTION: Administration of large volumes of fluids is associated with poor outcome in septic shock. Recent data suggest that non-resuscitation fluids are the major source of fluids in the intensive care unit (ICU) patients suffering from septic shock. The present trial is designed to test the hypothesis that a protocol targeting this source of fluids can reduce fluid administration compared w

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Microglial cells are brain-specific macrophages that swiftly react to disruptive events in the brain. Microglial activation leads to specific modifications, including proliferation, morphological changes, migration to the site of insult, and changes in gene expression profiles. A change in inflammatory status has been linked to many neurodegenerative diseases such as Parkinson's disease and Alzhei

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In recent years, the data science and remote sensing communities have started to align due to user-friendly programming tools, access to high-end consumer computing power, and the availability of free satellite data. In particular, publicly available data from the European Space Agency’s Sentinel missions have been used in various remote sensing applications. However, there is a lack of studies th

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Background Previous trials of interferon in multiple sclerosis (MS) have shown efficacy, but the degree of clinical benefit remains uncertain, and the optimum dose is not known. We undertook a double-blind, placebo-controlled study in relapsing/remitting MS to investigate the effects of subcutaneous interferon -1a. Methods 560 patients with Kurtzke expanded disability status scale (EDSS) scores o

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Requirements on radiating structures are constantly increasing, demand for faster speed, smaller size, and higher reliability drives today's technical development. However, for electrically small structures, less than half-a-wavelength in size, performance is fundamentally limited by physical size. This thesis explores how to construct and calculate physical bounds for advanced antennas and comple

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Plasma circulating cell-free mitochondrial DNA (ccf-mtDNA) is an immunogenic molecule and a novel biomarker of psychiatric disorders. Some previous studies reported increased levels of ccf-mtDNA in unmedicated depression and recent suicide attempters, while other studies found unchanged or decreased ccf-mtDNA levels in depression. Inconsistent findings across studies may be explained by small samp

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Background: Heart function following heart transplantation (HTx) is influenced by numerous factors. It is typically evaluated using transthoracic echocardiography, but reference values are currently unavailable for this context. The primary aim of the present study was to derive echocardiographic reference values for chamber size and function, including cardiac mechanics, in clinically stable HTx

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We use Monte Carlo simulations of a coarse-grained model to investigate structure and electrochemical behaviours at an electrode immersed in room temperature ionic liquids (RTILs). The simple RTIL model, which we denote the asymmetric restricted primitive model (ARPM), is composed of monovalent hard-sphere ions, all of the same size, in which the charge is asymmetrically placed. Not only the hard-

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Background: Standard treatment of localized squamous cell carcinoma of the anus (SCCA) is radiotherapy (RT) combined with chemotherapy, that is, chemoradiation (CRT). Primary surgery has a limited role, but is a recommended treatment for small well differentiated SCCA localized in the anal margin, with re-excision or postoperative RT/CRT in case of involved surgical margins. The evidence supportin