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The immune system is of central importance to clear-off pathogens in order to keep an organism healthy. In vertebrates, the Major Histocompatibility Complex (MHC) is a genomic region that holds key genes involved in adaptive immunity and in particular in the antigen presenting process. The presentation relies on MHC class I (MHC-I) and MHC class II (MHC-II) molecules that are encoded by MHC-I and

Enabling techniques for separating target cells, such as subgroups of white blood cells and cancercells from blood and other body fluids, are necessary for lab work facilitation, inline integration withhigh-end bioanalytical instrumentation, and for point-of-care or home testing. The work of this thesisaddresses this need by further studying an equilibrium-based ultrasonic wave-based technology ca

Structural defects in Mg-doped GaN were analyzed using high-resolution scanning transmission electron microscopy combined with electron energy loss spectroscopy. The defects, in the shape of inverted pyramids, appear at high concentrations of incorporated Mg, which also lead to a reduction in free-hole concentration in Mg doped GaN. Detailed analysis pinpoints the arrangement of atoms in and aroun

Seventy-nine monoclonal antibodies submitted to the ISOBM TD-3 PSA Workshop were tested for their reactivity with recombinant human kallikrein-2 (rhK2). A sandwich immunofluorometric assay using polyclonal antiprostate- specific antigen (PSA) antiserum-coated plates was used to capture rhK2 and subsequently the test antibody. The response of each test antibody was compared with 3 reference antibod

The transport sector accounted for 37% of global CO2 emissions from end-use sectors in 2021. For the transport- and road freight sector to contribute to emissions reduction targets while still meeting the foreseen increase in transport demands, decarbonization will play a key role. This study focus on battery-electric heavy-duty trucks and the objective is to provide an overview of policy instrume

2021 marked the 30-year anniversary of the publication Fatal Years: Child Mortality in the late Nineteenth-Century United States, a pioneering work in historical demography by Samuel H. Preston and Michael R. Haines. This special issue showcases the current state of historical mortality studies through a collection of articles originally presented at two commemorative sessions at the 2021 meeting

PURPOSE In developing countries, Hodgkin lymphoma (HL) affects the young population. In Ethiopia, nearly 70% of the population are, 35 years of age. Therefore, this study aimed to elucidate the age distribution, histopathologic patterns, clinical characteristics and treatment outcomes of HL in Ethiopia. MATERIALS AND METHODS Data from clinical records of 133 consecutive patients with HL between 20

PurposeDrylands account for 47.2% of land area and contain 15.5% of global carbon (C). However, the variation in organic and inorganic C stocks across latitudinal gradients in arid and semiarid shrubland ecosystems remains understudied, and we lack in-depth understanding of the main drivers of C variation at this spatial scale.MethodsHere, we sampled soils from 95 sites across a latitudinal gradie

One of the most important challenges for modern society is how to feed the world in a sustainable manner. Agriculture is an essential part of food production, but at the same time it has many negative impacts on the environment, through for example pollution, nutrient leaching, and greenhouse gas emissions, and it is a big driver of biodiversity loss. Organic farming is a farming system that in ma

Den internationella arenan domineras av stater. Staters existens är befäst i sedvanerätten genom Montevideokonventionen. Det har dock i ivern att hålla sig fast vid denna uppstått en uppfattning om att de kriterierna som krävs för att något kan anses vara en stat, också blir gällande e contrario i hänsyn till när stater ska anses upphöra att existera. En av de fyra kriterierna är kriteriet om terrThe global arena is dominated by states. The existence of a state is regulated in the Montevideo Convention on the Rights of States. There does however seem, that in the desire to follow this convention, a definitive opinion that states losing one of the criteria set up by the convention, also means losing their stateship, as a Montevideo Convention e contrario, if you will. One of these four crit

Ett väl fungerande skattesystem utgör basen för finansieringen av välfärdssystemet. Skatteflykt ger upphov till skattebaserosion, ett fenomen som ger upphov till stora kostnader, såväl för Sverige som för andra stater och försvårar finansieringen av välfärdssystemet. Generalklausuler utgör ett verktyg mot skatteflykt. I Sverige finns sedan många år tillbaka en generalklausul mot skatteflykt i skatThe basis for the funding of welfare systems is a well-functioning tax system. Tax base erosion, founded in tax avoidance, imposes significant costs for both Sweden and other countries and it risks obstructing the funding of the welfare system. General Anti-Avoidance Rules (GAARs) is an instrument for countering tax avoidance. For many years, Sweden has had a GAAR in the Swedish Anti-Avoidance Act

Konkurrensklausuler i anställningsavtal avser att begränsa arbetstagares rätt att fritt konkurrera efter avslutad anställning. Uppsatsen ämnar att bedöma om 2015 års överenskommelse om konkurrensklausuler är att betrakta som god sed på arbetsmarknaden. Denna fråga måste först besvaras innan uppsatsens huvudfråga kan besvaras, nämligen om perdurerande viten är tillåtna i konkurrensklausuler och om The purpose of a competition clause in a employment contract is to restrain the employees possibilities to compete with the former employer after he or she quits the employment. This study aims to assess if the 2015 collective agreement on competition clauses in employment contracts is to be regarded as good practice in the Swedish labor market i.e become binding on all employers and employees whe

Sverige har historiskt sett haft ett generöst konsolideringssystem för koncerner med stora avdragsmöjligheter. Avdragsmöjligheten för bland annat ränta har dock begränsats i allt större utsträckning på grund av viktigare samhällsintressen, så som ett förhindrande av skatteflykt och aggressiv skatteplanering. Ett resultat av detta är att det år 2019 trädde i kraft nya generella ränteavdragsbegränPreviously Sweden has had a generous consolidation system for groups with large deduction possibilities. However, the possibility of interest deductions, among other things, has increasingly been limited due to more important societal interests, such as preventing tax evasion and tax avoidance practices. As a result, new general interest limitation rules were put into practice in 2019 affecting

Introduction: There is a need for risk stratification of emergency department (ED) chest pain patients. The Global Registry of Acute Coronary Events risk score (GRACE RS) predicts adverse events in patients with confirmed acute coronary syndrome (ACS), and has been validated on unselected ED patients with chest pain. Clinical gestalt is the unstructured overall clinical assessment, based on the ph

The Base of the Pyramid (BoP) refers to 4 - 4,5 billion people in the world, who are living on less than a few dollars per day. This majority of the world's population has a little resources and is usually considered as a group with no purchasing power and therefore is currently unserved and underserved by current products and services. However, more than any others, the low-income consumers a

This is a Master Thesis about the use of mineral glass in mobile phone front windows. A brief introduction to glass as a material and its behavior is followed up by our own research and investigations. We have looked at existing and unreleased phones from Sony Ericsson that use or will use mineral glass. We have also examined some competitor phones. All gathered information was analyzed, sorte

This thesis drives a twofold argument about the Swedish policies on foreign aid and development. First of all is it stated how there has been a continuity in this particular field of policy has since its inception in the 1960s and the issue has in the closest become depoliticised in mainstream politics. With the intent of bringing this field of policy back in to the light of politics and ideology