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BACKGROUND: The aim was to improve the realism of patient models for Monte-Carlo based evaluation of image-based quantification of tumour volume and activity in [68Ga]Ga-DOTA-TOC PET and [177Lu]Lu-DOTA-TATE SPECT images.METHODS: Three phantoms from the XCAT population were used as basis. Tumour structures were obtained from segmentation of patient 68Ga-PET images and positioned at relevant positio
In the fast-evolving arena of climate finance, equitable access to and allocation of funds for adaptation continue to pose a significant and urgent challenge. In theory, to prepare for the impacts of climate change in an equitable way, regional, national, and European Union (EU) funding tenders on climate adaptation should prioritize the most climate-vulnerable local administrations. However, evid
Lignins are a polymeric, renewable resource with remarkable structural diversity. Research is being conducted into the valorisation of lignins into value-added products. The absence of experimental libraries, in particular for process-modified oligomers, hampers analytical feedback to these valorisation efforts. Stochastic methods for generating libraries in-silico have been proposed, but were not
Lime-cement mixing is a method used for ground improvement of clay soils. Before mixing at a field site, laboratory samples are prepared and tested to decide the amount of lime-cement binder needed to reach the desired material strength. Strength measurements are not possible before a sample hardens, and the test process to predict final strength takes 30 days. Resistivity measurements are possibl
Water hyacinth is among the world’s most damaging aquatic invasive plants, forming dense mats that disrupt ecosystem functioning, fisheries, navigation, and livelihoods across tropical and subtropical freshwater systems. Its rapid spread is driven by clonal propagation, short life cycles, and prolific seed production, particularly under nutrient-enriched conditions. Although mechanical, chemical,
OBJECTIVE: Avacopan (AVAC), an oral selective C5a receptor inhibitor, has been approved for treatment in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Outside randomized controlled studies, real-world data are scarce. The aim of this study was to provide further insight into the clinical experience of AVAC.METHOD: We analysed data from 16 patients with severe AAV include
Accurate mapping of earthquake-damaged buildings is essential for rapid post-disaster assessment and urban recovery planning. Very high-resolution (VHR) satellite imagery enables large-scale geospatial damage detection; however, conventional convolutional neural networks (CNNs) often struggle to model complex spatial dependencies and nonlinear damage patterns efficiently. To address these limitati
The Sendai Framework for Disaster Risk Reduction (2015–2030) promotes shared responsibility as a foundational principle for effective disaster governance, emphasizing the involvement of states, communities, private actors, and civil society. However, the principle faces criticism for its conceptual vagueness and practical limitations. This paper develops and applies a structured four-dimensional f
Liquidity constraints are often seen as a barrier to entrepreneurship, with many relying on personal or informal capital to start a business. This paper examines whether increased access to equity ─ via rising value of owner-occupied housing ─ affects the likelihood of business entry. Using detailed Swedish tax return data and exploiting the 2008 property tax reform as a natural experiment, we ana
Summary: Existing approaches to modelling antibody concentration data are mostly based on finite mixture models that rely on the assumption that individuals can be divided into 2 distinct groups: seronegative and seropositive. Here, we challenge this dichotomous modelling assumption and propose a latent variable modelling framework in which the immune status of each individual is represented along
Firms struggle to translate sustainability ambitions into innovation practices, especially in crisis contexts where leaders must navigate ambiguity, competing demands, and rapid change. This study examines how top managers use sense-related practices to cultivate an adaptive space for sustainability-oriented innovation (SOI) under crisis-induced conditions. Drawing on an in-depth, process-oriented
Previous research underscores the importance of addressing biodiversity loss within environmental justice, introducing the concept of multi-species justice (MSJ) to recognise the rights and agency of non-human species. Despite its theoretical foundation, practical applications of MSJ remain underexplored. This paper contributes to operationalising MSJ in climate adaptation by exploring barriers to
Background: The aim was to evaluate bias and precision for 177Lu-activity-quantification using window-based scatter compensation in a ring-configured CZT gamma camera (StarGuide™, GE HealthCare). This paper extends a previous study by applying modified scatter compensation (MSC) methods introduced with the StarGuidePlus upgrade. The modified methods account for contamination of scatter windows by
In a context of population ageing, housing crises and socio-spatial inequalities, ageing in place depends not only on dwellings but also on neighbourhood conditions. This article examines how older adults’ social possibilities are shaped in everyday life in Angered and Högsbo, two contrasting neighbourhoods in Göteborg, Sweden. Drawing on 12 walking interviews with older adults and 72 neighbourhoo
Cold extremes bring significant uncertainties to the energy system. Their strong spatiotemporal coupling introduces growing challenges to the adequacy and flexibility of the power and heating supply, complicating risk identification and mitigation. Therefore, this paper presents a framework for spatiotemporal risk assessment and resistance enhancement under cold extremes. It captures cold-air prop
Background: This retrospective cohort study compared short-term outcomes between robotic-assisted and conventional laparoscopic surgery for rectal cancer using data from the Swedish Colorectal Cancer Registry. Method: All patients undergoing elective minimally invasive surgery for rectal cancer between 2014 and 2021 and registered in the Swedish Colorectal Cancer Registry were assessed for eligibi
Wildlife-vehicle collisions (WVCs) pose significant risks to highway safety and wildlife populations, leading to considerable economic losses. However, efforts to systematically characterize and mitigate WVCs are often constrained by substantial under-reporting in official crash record databases. This study integrates police-reported crash data with carcass removal records from 7041 road segments
