Filtyp
Context: Value stream mapping (VSM) as a tool for lean development has led to significant improvements in different industries. In a few studies, it has been successfully applied in a software engineering context. However, some shortcomings have been observed in particular failing to capture the dynamic nature of the software process to evaluate improvements i.e. such improvements and target value
A prototype of a surface emissions trap, a new device for reducing emissions of volatile organic compounds and particulate matter from surfaces while allowing evaporation of moisture, was used to improve the indoor air quality of a school building with elevated air concentrations of 2-ethyl-1-hexanol. A clear improvement of the perceived air quality was noticed a few days after the trap had been a
The autoantigen of endomysial antibodies in coeliac disease has been found to be an enzyme, tissue transglutaminase. Zinc inhibits the calcium-dependent activation of this thiol enzyme and also decreases the affinity between transglutaminase and the antibodies. Physiologically, transglutaminases catalyse the formation of bridges between lysine- and glutamine-containing peptides. Theoretically, if
De senaste åren har det blivit tydligt att detaljhandeln av idag måste hantera två förändringstryck: ökande internethandel och hållbarhetshänsyn. Hur fristående fysiska butiker och kedjor hanterar dessa tryck kommer att få avgörande betydelse för deras överlevnad. I detta kapitel argumenteras för att det finns en framtid för den fysiska butiken om miljöhänsyn tas på allvar ihop med de möjligheter
How do we perceive object motion during self-motion using visual information alone? Previous studies have reported that the visual system can use optic flow to identify and globally subtract the retinal motion component resulting from self-motion to recover scene-relative object motion, a process called flow parsing. In this article, we developed a retinal motion nulling method to directly measure
Direct searches for lepton flavour violation in decays of the Higgs and Z bosons with the ATLAS detector at the LHC are presented. The following three decays are considered: H→ eτ, H→ μτ, and Z→ μτ. The searches are based on the data sample of proton–proton collisions collected by the ATLAS detector corresponding to an integrated luminosity of 20.3 fb - 1 at a centre-of-mass energy of s=8 TeV. No
Colonoscopy plays a key role in the work-up of digestive diseases and constitutes the cornerstone in colorectal cancer diagnosis and prevention. Data suggest that the quality of colonoscopy varies widely between different endoscopists. This article summarizes current evidence and expert consensus on quality indicators, along with the evidence supporting their use in benchmarking, quality reporting
Meteorite impacts, one of the most ubiquitous processes in the solar system, have the ability to destroy as well as create habitats for life. The impact process can increase the translucency and porosity of the target substrate, as well as mobilize biologically relevant elements within the substrate. For endolithic organisms, this process has important implications, especially in extreme environme
An implantable sensor capable of long-term monitoring of tissue glucose concentrations by wireless telemetry has been developed for eventual application in people with diabetes. The sensor telemetry system functioned continuously while implanted in subcutaneous tissues of two pigs for a total of 222 and 520 days, respectively, with each animal in both nondiabetic and diabetic states. The sensor de
On Earth, the deep subsurface biosphere of both the oceanic and the continental crust is well known for surviving harsh conditions and environments characterized by high temperatures, high pressures, extreme pHs, and the absence of sunlight. The microorganisms of the terrestrial deep biosphere have an excellent capacity for adapting to changing geochemistry, as the alteration of the crust proceeds
Correct phenotypic interpretation of variants of unknown significance for cancer-associated genes is a diagnostic challenge as genetic screenings gain in popularity in the next-generation sequencing era. The Critical Assessment of Genome Interpretation (CAGI) experiment aims to test and define the state of the art of genotype-phenotype interpretation. Here, we present the assessment of the CAGI p1
Objective: Insulin release from pancreatic β-cells is controlled by plasma glucose levels via mitochondrial fuel metabolism. Therefore, insulin secretion is critically dependent on mitochondrial DNA (mtDNA) and the genes it encodes. Mitochondrial transcription factor B2 (TFB2M) controls transcription of mitochondrial-encoded genes. However, its precise role in mitochondrial metabolism in pancreati
Different approaches to anion exchange membranes (AEMs) are currently intensively investigated with the aim to develop materials for application in electrochemical energy devices such as alkaline fuel cells and electrolysers.1 One of the major challenges is to identify feasible synthetic strategies to AEM materials with sufficient long-term chemical and thermal stability. Studies of different smal
In Torfs et al. (2017) a new unified framework to model settling tanks in water resource recovery facilities was proposed providing a set of partial differential equations (PDEs) modelling different settling unit processes in wastewater treatment such as primary and secondary settling tanks (PSTs and SSTs). The extension to a multi-class framework to deal with the distributed properties of the set
BACKGROUND AND OBJECTIVES: To study selective regional binding for tau pathology in vivo, using PET with [(11) C]PBB3 in PSP patients, and other conditions not typically associated with tauopathy.METHODS: Dynamic PET scans were obtained for 70 minutes after the bolus injection of [(11) C]PBB3 in 5 PSP subjects, 1 subject with DCTN1 mutation and PSP phenotype, 3 asymptomatic SNCA duplication carrie
