Sökresultat

In unsparing efforts to find the hidden primaries, second primary cancers (SPCs) unrelated to cancer of unknown primary (CUP) are found. The detection rates of SPCs after CUP can be considered as measures for the effectiveness of modern diagnostic techniques in finding tumors. We aimed to compare the rates of specific SPCs found after the work-up of CUP and the more sign/symptom-directed diagnosti

Although extensive research has demonstrated host-retrovirus microevolutionary dynamics, it has been difficult to gain a deeper understanding of the macroevolutionary patterns of host-retrovirus interactions. Here we use recent technological advances to infer broad patterns in retroviral diversity, evolution, and host-virus relationships by using a large-scale phylogenomic approach using endogenou

Over the past 30 years a vast number of studies have demonstrated the presence of pharmaceutical residues in the environment. But still knowledge is scarce regarding the interaction of these emerging pollutants with various matrices in nature. A chromatographic system with on-line detection was devel- oped to perform a sorption study of six selected pharmaceuticals to four natural sediments and de

The Eurasian spruce bark beetle, Ips typographus, is one of the major forest insect pests in Europe, capable of mass-attacking and killing mature Norway spruce trees. The initiation and development of a new generation are strongly controlled by temperature and a warmer climate may affect the number of generations that is produced per year and hence the outbreak dynamics. Experimental knowledge reg

Modelling the formation of super-km-sized planetesimals by gravitational collapse of regions overdense in small particles requires numerical algorithms capable of handling simultaneously hydrodynamics, particle dynamics and particle collisions. While the initial phases of radial contraction are dictated by drag forces and gravity, particle collisions become gradually more significant as filaments

File sharing programs have changed the music industry in the last few years, as a lot of Internet users have started to download music. While the access to music has spread though the population of most countries, music sales have also dropped. The music industry has been pressuring political institutions to change laws to protect music copyrights. Sweden and Spain are two different countries with

When grief finds new ways - a qualitative study about grief blogs The purpose of this study was to examine why people who suffer from grief chooses to share their experiences through blogs on the Internet. Furthermore and by studying the blogs we intended to gain understanding of the advantages and disadvantages that blogging can bring to the bloggers. The study is based on a qualitative analysis

Varje år får cirka 50 000 svenskar diagnosen cancer. Mot detta är strålbehandling en vanlig behandlingsmetod och det uppskattas att cirka en tredjedel av alla som får cancer någon gång under sin behandling får strålbehandling. En viktig sak inom strålbehandling är att patienten får den dos som läkaren har ordinerat. Detta är en så vital detalj inom strålbehandling att SSI, Statens StrålskyddsinsIndependent dose calculations in radiotherapy are important as they help assure that the dose given to the patient is the same as the prescribed. The current version of software Radiation Verification Programme, RVP, does not take into account the effects that occur when a beam from a linear accelerator is moved off-axis. The aim with this project was to find a model for these effects, fit the par

Many biological and neural systems can be seen as networks of interacting periodic processes. Importantly, their functionality, i.e., whether these networks can perform their function or not, depends on the emerging collective dynamics of the network. Synchrony of oscillations is one of the most prominent examples of such collective behavior and has been associated both with function and dysfuncti

Trots att en domstolsförhandling är av stor vikt för många barn som har utsatts för sexuella övergrepp visar undersökningar att endast tio procent av anmälningarna om sexualbrott mot barn leder till åtal. Syftet med denna uppsats är dels att presentera de åtgärder som företas i förhållande till målsäganden under förundersökningen, dels att fastställa om det finns faktorer som är avgörande för huruA trial is very important for children who have been sexually abused, however studies show that only ten percent of police reports lead to a prosecution. The purpose of this essay is to discuss the current procedure for investigating reports of sexual abuses against children. The paper will determine whether there are factors that are relevant if a case is prosecuted or not and thus can contribute

Nitrogenase is the only enzyme that can convert N2 into NH3. The reaction requires the addition of eight electrons and protons to the enzyme and the mechanism is normally described by nine states, E0–E8, differing in the number of added electrons. Experimentally, it is known that three or four electrons need to be added before the enzyme can bind N2. We have used combined quantum mechanical and mo

Most recent programming languages include a collection framework as part of their standard library (or runtime). Examples are Java, C#, Python and Ruby. The Java Collection Framework provides a number of collection classes, some of which implement the same abstract data type, which makes them interchangeable. Developers can therefore choose between several functionally equivalent options. Since co

There is growing evidence that the environment experienced by one generation can influence phenotypes in the next generation via transgenerational plasticity (TGP). One of the best-studied examples of TGP in animals is predator-induced transgenerational plasticity, whereby exposing parents to predation risk triggers changes in offspring phenotypes. Yet, there is a lack of general consensus synthes

Background: Extracellular vesicles (EV) are nano-sized membranous structures released from most cells. They have the capacity to carry bioactive molecules and gene expression signals between cells, thus mediating intercellular communication. It is believed that EV confer protection after ischemic preconditioning (IPC). We hypothesize that myocardial ischemic preconditioning will lead to rapid alte

For the past four decades the compositional organization of the mammalian genome posed a formidable challenge to molecular evolutionists attempting to explain it from an evolutionary perspective. Unfortunately, most of the explanations adhered to the "isochore theory," which has long been rebutted. Recently, an alternative compositional domain model was proposed depicting the human and cow genomes

The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing uncertainty concerning optimal approaches to wound healing. The International Working Group of the Diabetic Foot (IWGDF) working group on wound healing has previously published systematic reviews of the evidence in 2008, 2012 and 2016 to inform protocols for routine care and to highlight areas which should be

Purpose: The purpose of this paper is to link humanitarian logistics (HL) and supply chain risk management (SCRM) to provide an understanding of risk mitigation strategies that humanitarian organisations use, or could use, to improve their logistics preparedness. Design/methodology/approach: Based on systematic reviews of RMS in SCRM and supply chain strategies (SCS) in HL literature, a framework

BACKGROUND: The progression of dementia disease implies increasing needs for both informal and formal care and services but also risk of institutionalisation. To better adjust care and services in the phase preceding institutionalisation it is important to find out whether utilisation of formal and informal care and services is determined by increased needs and by who meets the needs.AIM: The aim