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Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and metastasis. High levels of both uPA and PAT-1 are associated with poor prognosis in breast cancer patients. To confirm the prognostic value of uPA and PAI-1 in primary breast cancer, we reanalyzed individual patient data provided by members of the European Organization for Re

Background: Insulin-like peptide 3 (INSL3) is a constitutive hormone secreted in men by the mature Leydig cells of the testes. It is an accurate biomarker for Leydig cell functional capacity, reflecting their total cell number and differentiation status. Objectives: To determine the ability of INSL3 to predict hypogonadism and age-related morbidity using the EMAS cohort of older community-dwelling

The dielectric continuum model has rightfully been and continues to be a major workhorse for theory and modelling in Surface and Colloid Chemistry. Due to the implicit description of water, entering only as a scaling constant for charge-charge interactions, one would not expect it to work for short distances. However, considerable evidence has been accumulated over the years which shows that t

Osteoarthritis (OA) is the most common form of arthritis and often causes pain and functional impairment. Despite its high burden on society, knowledge about the occurrence of OA and its associated mortality is sparse. The epidemiology of OA is difficult to determine due to the patients’ fluctuating symptoms and challenges in detecting and defining the radiographic disease. The specific aims of th

OBJECTIVES: To compare different forms and ratios of serum prostate-specific antigen (PSA) to determine which form or ratio provides optimal diagnostic specificity and sensitivity in distinguishing between benign prostatic hyperplasia (BPH) and clinically localized prostate cancer. METHODS: Serum samples were obtained from 47 patients with BPH and 39 with clinically localized prostate cancer. Pati

Sweden has a significant rental sector with about a third of the total number of households rented out. The intention of the rental market should be that it is accessible to all people in society, regardless of nationality or income. The general mediation of rental apartments today is through a queuing system, which in Stockholm shows that a queuing time can be up to half one's life. The alter

In our society, digital cameras are used for a countless number of different purposes. There are many components going in to making such a complex product but one could argue that the camera sensor and lens make out the heart of a digital camera. Axis Communications AB, founded in 1984, is a Swedish company which pioneered and specialize in digital network cameras. In 1996 Axis delivered the first

Linking conflict events and cropland development in Afghanistan, 2001 to 2011, using MODIS land cover data and Uppsala Conflict Data Programme This thesis describes changes in land cover between 2001 and 2011 in Afghanistan, and analyzes the influence of conflict events on cropland development. How did fighting intensity affect cropland areas in Afghanistan, did cropland areas decrease or incre

Alla kvinnor i Sverige har rätt till ett liv fritt från könsbaserat våld i nära relation. Sedan början av 1990-talet har den svenska staten sett det som ett prioriterat jämställdhetsmål att utrota allt könsbaserat våld för att uppnå full jämställdhet mellan könen. Dock finns det en grupp med kvinnor som tvingas välja mellan att stå ut med våld i nära relation eller att bli utvisad. Flertalet rappoAll women in Sweden have the right to a life free from gender-based violence in close relationships. Since the early 1990s, the Swedish government sees the goal to eradicate all gender-based violence as a priority, to achieve full equality between the sexes. However, there is a group of women who are forced to choose between putting up with domestic violence or being deported. Several reports from

Background: Pancreatic cancer and other pancreaticobiliary type periampullary adenocarcinomas have a dismal prognosis even after resection and neoadjuvant chemotherapy. Intestinal type periampullary adenocarcinomas generally have a better prognosis, but little is known on optimal neoadjuvant and adjuvant treatment. New prognostic and treatment predictive biomarkers are needed for improved treatmen

Target-specific molecular imaging with radiolabeled antibodies has experienced a rapid growth over the past 20 years, and is now an essential tool to provide information on disease presence and extent. Despite all efforts to detect and control prostate cancer at an early stage, a number of men are still progressing to develop incurable metastatic disease. Because of this, development of new method

By international standards, children in Sweden experience good health. Sweden has low infant mortality rates, low accident mortality rates, a high number of breastfed children and a high proportion of vaccinated children. However, during the past twenty years the prevalence of overweight children has doubled in Sweden, while that of obese children has increased 4-5 times. Furthermore, there has be

Background: Children with Down syndrome (DS) have an increased risk for acute lymphoblastic leukemia (ALL). Although previous studies have shown that DS-ALL differs clinically and genetically from non-DS-ALL, much remains to be elucidated as regards genetic and prognostic factors in DS-ALL. Methods: To address clinical and genetic differences between DS-ALL and non-DS-ALL and to identify prognosti

Iterative decoding methods allow efficient decoding of long codes that are composed of smaller component codes. As a result reliable communication can be achieved with low decoding complexity even for rates close to Shannon capacity. This makes iteratively decodable codes a very attractive object of study in modern coding theory. This thesis focuses on different kinds of cycles which appear in th

In this thesis, the Lebanese legal system is presented using a comparative approach, with emphasis on its French influence and rapprochement to European Community law. The republic of Lebanon was formally established in 1943, following a French mandate period sanctioned by the League of Nations in 1920. During this period most of the legal institutions and material rules and codes that characteriz

The notion of organizations as learning entities has gained considerably in popularity over the last decade, and is now regarded an important issue both theoretically and in practice. Many organizational activities and events have been referred to as learning phenomena, and learning theory is being applied to increasingly varied and complex settings of organizational life. This divergence would su

Background: Prostate-specific antigen (PSA) has modest specificity for prostate cancer. A panel of four kallikrein markers (total PSA, free PSA, intact PSA, and kallikrein-related peptidase 2) is a highly accurate predictor of biopsy outcome. The clinical significance of biopsy-detectable cancers in men classified as low-risk by this panel remains unclear. Methods: The Malmo Diet and Cancer study

Popular Abstract in Swedish Reformationens budskap brukar karakteriseras med hjälp av några "allena": Kristus allena, tron allena, nåden allena och Skriften allena. I denna studie undersöks hur Martin Chemnitz (1522-86) behandlar dessa teman och hur han sätter dem i relation till Augustinus teologi. Martin Chemnitz var en av de mest framstående evangeliska teologerna i generationen efter Martin LuAs a co-author of the Formula of Concord, Martin Chemnitz (1522-86) codified the sola scriptura principle of the Reformation, that the prophetic and apostolic Scriptures are the only rule for all Church doctrine. This principle is clearly expressed in Chemnitz' own theological treatises as well, but in his argumentation one is also confronted with an astonishing number of quotations from the Churc

Background. The development of fluid and salt retention is a potential problem for all peritoneal dialysis (PD) patients. Sodium removal by the peritoneum is predominantly determined by convective fluid loss but influenced by diffusion and sieving due to free water transport as predicted by the three-pore model (TPM). The aim of the study was to establish the effect of transport status, dwell leng

A polyion-surfactant ion complex salt, cat-HECDS, has been synthesised, consisting of cationic hydroxyethyl cellulose w th dodecylsulfate counterions. Ternary phase diagrams have been established for aqueous mixtures of cat-HECDS with either the conventional surfactant NaDS or the polyelectrolyte cat-HECCl. Such mixtures represent the simplest possible aqueous mixtures of oppositely charged polyme