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Label-free cell tracking

Migrating cells under various force fields in microfluidic devices has been used as a tool to study the cell properties. Cells respond to the same force field in different ways depending on their properties, resulting in different migration velocities and trajectories which are obtained by cell tracking. The cells that are to be tracked are typically labelled with fluorescent dyes to enhance the c

Meta-Analysis of Digital Transformation in Organisations

The ongoing surge in internet users worldwide and its complexity causes organisations to digitally transform to stay competitive. Previous research repeatedly emphasised the importance of digital transformation, but the authors see a gap in the literature regarding digital transformation. General change management models have been around, but a more focused framework for digital transformation is

Omedveten oaktsamhet i mål om oaktsam våldtäkt

Sedan den 1 juli 2018 bygger våldtäktslagstiftningen i Sverige på frivillig-het, eller samtycke, som det kallas i både facklitteratur och populärkultur. Detta innebär att det som numera ligger i fokus är gärningsmannens uppsåt till det faktum att den andra personen inte deltar frivilligt i en sexuell handling. En annan förändring som gjordes vid införandet av den nya lag-stiftningen var att våldtäIn 2018, Sweden passed a new law regarding rape, which is based on the lack of voluntary participation or in other words, consent. This means that it is now the perpetrators intent, regarding that the other person does not participate voluntarily in the sexual act, which lays in the court judgements focus. Another change was that a new offense where passed, negligent rape. Thus, criminal liability

Safety and Security in Sudan: Humanitarian Aid Workers’ Risk Perception

Protection of humanitarian aid workers (HAWs) is a challenging task. There are various reports on the topic where much research seems to focus on traditional physical attacks and intentional violence against HAWs (security) rather than the accidental event risks (safety) or discussing it separately. These risks are usually defined by the organization’s security risk management holding the power in

Att straffa eller inte straffa - Om straffansvar för otjänliga försök i svensk och dansk straffrätt

Med utgångspunkt i en rättsdogmatisk metod har denna framställning syftat till att utreda gällande rättsläge beträffande otjänliga försök inom dansk och svensk straffrätt. Mer specifikt är det straffansvarets omfattning vid otjänliga försök som undersökts genom en kritisk komparation mellan svensk och dansk rätt. Som en konsekvens av en vag lagtext i 23 kap. 1 § BrB är otjänliga försök inom svenBy a legal dogmatic method, this thesis has intended to investigate the legislation in force regarding harmless attempted crimes within Danish and Swedish criminal law. More specifically, the scope of criminal liability in the case of harmless attempts has been examined through a critical comparison between Swedish and Danish law. Harmless attempted crimes are because of an indistinct text of la

Kravet på överklagbarhet - Förvaltningsmyndigheters beslut som exekutionstitlar

Den 1 september 2022 trädde en ändring i utsökningsbalken i kraft, med följden att förvaltningsmyndigheters beslut som huvudregel utgör exekutionstitlar, förutsatt att beslutet dels innehåller en betalningsförpliktelse, dels är överklagbart. Före lagändringen krävdes en särskild föreskrift för att ett sådant beslut skulle utgöra en exekutionstitel. Ändringen skedde i syfte att effektivisera verkstOn the 1st of September 2022 an amendment in the Swedish Enforcement Code (1981:774) came into effect, with the result that an administrative decision today as a general rule becomes an enforcement title, under the condition that it contains an obligation of payment as well as being appealable. The purpose of this amendment to the law was to bring about a more effective enforcement procedure conce

A Concept Proposal of a New Generation Operator Panels

This project was done for the company Beijer Electronics Products AB and the task was given by the hardware development department of the company. The project was about developing a concept proposal for a new generation operator panels. This was done to inspire the product developers at Beijer Electronics with innovative ideas before the actual operator panel development. More in detail the object

Massive MIMO performance evaluation based on measured propagation data

Massive MIMO, also known as very-large MIMO or large-scale antenna systems, is a new technique that potentially can offer large network capacities in multi-user scenarios. With a massive MIMO system, we consider the case where a base station equipped with a large number of antenna elements simultaneously serves multiple single-antenna users in the same time-frequency resource. So far, investigatio

Examestane in advanced or recurrent endometrial carcinoma: a prospective phase II study by the Nordic Society of Gynecologic Oncology (NSGO)

Background: We evaluated the efficacy and safety of the aromatase inhibitor exemestane in patients with advanced, persistent or recurrent endometrial carcinoma. Methods: We performed an open-label one-arm, two-stage, phase II study of 25 mg of oral exemestane in 51 patients with advanced (FIGO stage III-IV) or relapsed endometrioid endometrial cancer. Patients were stratified into subsets of estro

Sunnybrook and House-Brackmann Systems in 5397 Facial Gradings

Objectives. To study the correlation between Sunnybrook and House-Brackmann facial grading systems at different time points during the course of peripheral facial palsy. Study Design. Prospective multicenter trial. Setting. Seventeen otorhinolaryngological centers. Subjects and Methods. Data are part of the Scandinavian Bell's palsy study. The facial function of 1920 patients with peripheral facia

Beta-microseminoprotein in serum correlates with the levels in seminal plasma of young, healthy males

Beta-microseminoprotein (MSP) is one of the most abundant proteins secreted by the prostate gland. Because MSP is also synthesized in nonreproductive organs, the establishment of a solid relationship between the levels of MSP in serum and semen is crucial for future studies connecting MSP with aging or diseases of the prostate gland. We developed a specific, competitive, europium-based immunoassay

Peg-IFN and ribavirin treatment for recurrence of genotype 2 and 3 hepatitis C after liver transplantation

Background: Relapse of hepatitis C virus (HCV) infection after liver transplantation (LT) is universal. Tolerance for treatment with pegylated-interferon (peg-IFN) and ribavirin (RBV) is suboptimal and withdrawals due to adverse events frequent. We sought to improve tolerance for treatment to improve outcome. Methods: We used concentration-guided RBV dosing to achieve an intended 10 mu mol/L conce

Return to work after work after a workplace-oriented intervention for patients on sick-leave for burnout - a prospective controlled study

Background: In the present study the effect of a workplace-oriented intervention for persons on long-term sick leave for clinical burnout, aimed at facilitating return to work (RTW) by job-person match through patient-supervisor communication, was evaluated. We hypothesised that the intervention group would show a more successful RTW than a control group. Methods: In a prospective controlled study

Isolated hepatic perfusion as a treatment for uveal melanoma liver metastases (the SCANDIUM trial): study protocol for a randomized controlled trial

Background: Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will ultimately develop in approximately 50% of patients, with the liver being the most common site for metastases. The median survival for patients with liver metastases is between 6 and 12 months, and no treatment has in randomized trials eve

Causes of death in patients with extranodal cancer of unknown primary: searching for the primary site

Background: Cancer of unknown primary (CUP) is a fatal cancer, accounting for 3-5% of all diagnosed cancers. Finding the primary site is important for therapeutic choices and we believe that the organ which is designated as the cause of death may give clues about the primary site. Methods: A total of 20,570 patients with CUP were identified from the Swedish Family-Cancer Database. Causes of death

Difficult cannulation as defined by a prospective study of the Scandinavian Association for Digestive Endoscopy (SADE) in 907 ERCPs

Background. The definition of a "difficult" cannulation varies considerably in reports of endoscopic retrograde cholangiopancreatography (ERCP). Aims. To define a difficult cannulation, which translates into higher risk of post-ERCP pancreatitis. Patients and methods. Prospective consecutive recording of 907 cannulations in Scandinavian centers done by experienced endoscopists. Inclusion: indicati

Stability of PCR Targets for Monitoring Minimal Residual Disease in Neuroblastoma

In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper

Use of Inhaled Corticosteroids in Patients With COPD and the Risk of TB and Influenza A Systematic Review and Meta-analysis of Randomized Controlled Trials

Background: The use of inhaled corticosteroids (ICSs) is associated with an increased risk of pneumonia in patients with COPD. However the risks of other respiratory infections such as TB and influenza remain unclear. Methods: Through a comprehensive literature search of MEDLINE EMBASE CINAHL Cochrane Library and ClinicalTrials.gov from inception to July 2013 we identified randomized controlled tr