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Background. The urokinase plasminogen activator (uPA) system is involved in tissue remodelling processes and is up-regulated in many types of malignancies. We investigated whether serum levels of different forms of soluble uPA receptor (suPAR) are associated with survival and in particular with prostate cancer and cardiovascular disease mortality. Methods. Using time-resolved fluorescence immunoas
Background: Different tau biomarkers become abnormal at different stages of Alzheimer’s disease (AD), with CSF p-tau typically being elevated at subthreshold levels of tau-PET binding. To capitalize on the temporal order of tau biomarker-abnormality and capture the earliest changes of tau accumulation, we selected a group of amyloid-β-positive (A+) individuals with elevated CSF p-tau levels but ne
We summarize the theory and implementation of an open source solver for rotationally symmetric scatterers. The purpose of the code is to compute reference solutions for electrically large radome problems. The rotational symmetry decouples the azimuthal modes, enabling the three-dimensional problem to be broken down into a sequence of decoupled two-dimensional problems which require much less memor
AIMS/HYPOTHESIS: The aim of this work was to explore associations between type 1 diabetes progression from stages 1 or 2 to stage 3 and interacting ligand-receptor complexes of HLA class I (HLA-I) and KIR gene products.METHODS: Applying next-generation sequencing technology to genotype HLA-I genes (HLA-A, -B, -C) and KIR genes (KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5, KIR2DS1, KIR2DS2, KIR2DS3
Previously proposed high spin states in Na22,23 are compared with calculations from the cranked Nilsson model including Strutinsky renormalization. High K rotational isomers are proposed for Iπ=6- in Na22 and 11/2+, 13/2+, and possibly 15/2+ in Na23. The positive parity yrast sequences in these two nuclei are analyzed in terms of the change from collective to single particle behavior at I=9 (22Na)
Popular Abstract in English Alcohols and aldehydes are used in the chemical industry largely as a starting material for the manufacture of a wide range of products. They are also used as such in various industrial applications. The flexibility is due mainly to the functionalities of the alcohols and aldehydes being hydroxylic and carbonylic, respectively. Much interest is directed nowadays at convNowadays, transition metal oxide catalysts are employed to a large extent in many chemical processes for the selective production of chemicals and intermediates. Although metal oxides are mostly known as oxidation catalysts, they can successfully catalyze a wide range of reactions, such as dehydration. Two different processes have been studied in the present work: the selective oxidation of methan
Computer programming should be expressing the complicated in easily understandable parts. General languages provide tools and abstractions that allow many different problems to be formulated and solved. Unfortunately, these abstraction only rarely match the problem area precisely, resulting in solutions that are obscured by the need for support code unrelated to the problem. This can be avoided, b
Microsoft Word - Conference May 7-8 Sustainable Welfare.docx Conference May 7-8 Sustainable Welfare This expert workshop addresses the question of what is required to make welfare societies ecologically sustainable. The purpose of the workshop is to join research on welfare and sustainability, which until now has been carried out separately and in isolation with little contact and cross-fertilizat
https://www.pi.lu.se/sites/pi.lu.se/files/conference_may_7-8_sustainable_welfare.pdf - 2026-07-17
In conventional MIMO, propagation conditions are often considered wide-sense stationary over the entire antenna array. In massive MIMO systems, where arrays can span over large physical dimensions, the situation is quite different. For instance, significant variations in signal strength, due to shadowing, can be experienced across a large array. These effects vary with propagation environment in w
The people bordering the Arabian Gulf, the Mediterranean Sea and the Red Sea rely more and more on seawater desalination for safe water supply. Desalination has advantages and disadvantages which to a large extent depend on the region, location, technology, impact and amount of fresh water production. In this region, some 60% of all desalination capacity is installed. The three regions areas repre
Variations in molybdenum isotopic composition, spanning the range of similar to 2.3 parts per thousand in the terms of Mo-97/Mo-95 ratio, have been measured in sediment cores from three lakes in northern Sweden and north-western Russia. These variations have been produced by both isotopically variable input of Mo into the lakes due to Mo isotopic heterogeneity of bedrock in the drainage basins and
The Major Intrinsic Proteins, MIPs, constitute a large, ancient superfamily of membrane proteins that are found in all kingdoms of life. Most MIPs facilitate passive diffusion of water across biological membranes (aquaporins), although many channels are also permeable for glycerol and other small uncharged solutes, (aquaglyceroporins). Other substrates reported for specific MIPs are anions, carbon
Paul Ricœur was widely regarded as one of the great contemporary French philosophers and as a leading intellectual who produced during his long life influential works in numerous scholar fields ranged from phenomenology and hermeneutics, psychoanalysis and poetics to theology and ethics. In his philosophical works he was deeply concerned with the meaning of life, in particular with our constant an
Popular Abstract in Swedish I Sverige analyseras omkring 40 000 DNA-prover från brottsplatser varje år. DNA-profilerna jämförs mot DNA-profiler från misstänkta personer och kan på så vis användas för att knyta en person till ett brott. Alla typer av kroppsvävnader kan analyseras, såsom blod, saliv och hudceller. Vanliga bevismaterial är cigarettfimpar, flaskor, burkar och kläder. De material som cDNA evidence, linking perpetrators to crime scenes, is central to many legal proceedings. However, crime scene samples often contain extraneous substances that may interfere with the PCR-based forensic analysis, resulting in partial or negative DNA profiles. Extensive DNA purification may remove inhibitors, but involves the risk of DNA loss. In this work, pre-PCR processing was applied to improve
