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I dagens globala ekonomi råder det konkurrens om den högkvalificerade arbetskraften. Det är ett särskilt stort problem att attrahera denna lättrörliga personkategori till högskatteländer som Sverige och Danmark. Båda länderna har därför infört särskilda skattelättnader riktade mot denna personkrets. Den svenska expertskatten är reglerad i 11 kap 22-23 a §§ inkomstskattelagen och den danska forskerHigh-skilled workers are greatly valued on the global labor market. As a result, a number of countries have introduced targeted tax concessions for high-skilled labor in order to attract this particular part of the workforce. This is especially true for high-tax countries, concerned that the high tax rates dis¬courage high-skilled workers from locating in a particular country. Sweden and Denmark a

To most people bitumen is an unknown material although it is the most important ingredient in asphalt pavements, something that everyone knows and uses every day. By merely distilling crude oil a substance is produced with unique properties and durability, which could not have been produced by synthetic means, at least not in those quantities used. The production is not that simple and the raw mat

Acute myeloid leukemia (AML) is a highly heterogeneous blood disease which is characterized by different mutations and chromosomal rearrangements. Nearly 60% of genetic alterations have been found in AML patients involve in signaling pathways including signaling of tyrosine kinase receptor FLT3. FLT3 mutations emerged as one of the most common mutations in AML which represent around 35% of all AML

Inflammatory airway diseases and lower respiratory tract infections are leading causes of severe illness, disability and death worldwide. Much of today´s hypotheses about the underlying inflammatory processes and pathogenic contribution by immune cells come from in vitro experiments or animal models. As a consequence, our knowledge of the actual immunopathological events in real patient tissues is

The tumor microenvironment consists of several interacting cell types. Cancer research focssed mainly on the malignant cell in the past. The importance of the tumor microenvironment is increasingly appreciated, as endothelial cells and immune cells were identified as targets for anti-tumor therapy. Targeted therapy against cancer-associated fibroblasts (CAFs) are not in clinical use for the treatm

Klimatförändringarna kommer att påverka ekosystem och samhällen över hela världen. Det är ett problem som kräver drastiska och omedelbara förändringar av vårt sätt att leva och av våra samhällsstrukturer, och därmed politiskt engagemang av aldrig tidigare skådat slag. Under de senaste 30 åren, sedan bildandet av Förenta Nationernas ramkonvention om klimatförändringar (Klimatkonventionen; UNFCCC) åThe rise of climate change as an issue of global concern has rested on scientific representation and understanding of the causes and impacts of, and responses to climatic change. The Intergovernmental Panel on Climate Change (IPCC), in particular, has been central to how climate change has become known as a global political problem. This thesis aims to critically examine the production, negotiatio

The purpose of this thesis is to analyze how the ongoing controversy surrounding the Internet, the phenomena of digitalization and file sharing will affect the music industry in the form of the “big five“ labels. Furthermore the thesis aims to present a recipe of strategies for the companies’ survival by studying their situation through a theoretical perspective in conjunction with a comparative a

Pollen analyses and AMS C-14 measurements were performed on lacustrine sediments and peat sequences from two former crater lakes (Preluca Tiganului, Steregoiu) situated in the Gutaiului Mountains in northwestern Romania, in order to reconstruct the vegetation development during the Lateglacial and Early Holocene. Before c. 14,700 cal. years BP (GS-2) open vegetation with shrubs (Salix, Juniperus),

Popular Abstract in Swedish Närmare 30.000 svenskar drabbas årligen av stroke (slaganfall). I ungefär 85 % av fallen är orsaken en blodpropp i ett av hjärnans kärl s.k. hjärninfarkt. En avstängning av blodflödet orsakar en snabbt insättande förlust av funktionen i det drabbade området, t.ex. halvsidig förlamning, bortfall av delar av synfältet liksom störning av olika högre hjärnfunktioner såsom mAbstract Stroke is the third leading cause of death in the western world, and the number one cause of disability. 85% of all strokes are ischemic. Most stroke survivors will experience recovery of function. The mechanisms behind this improvement are partly unknown, but may involve elements of both compensation and restoration. Exposure to an enriched environment (EE) that stimulates social interac

Today, as a rule, the most cost-effective way to remove nitrogen from municipal wastewater is the biological method based on nitrification and subsequent denitrification. All biological systems may be affected by toxicants, and biological nitrogen removal is no exception. An investigation of influent wastewaters from 109 Swedish municipal wastewater treatment plants was accomplished. Inhibitory s

The work presented in this thesis focuses on developing methods of measuring moisture properties at high moisture levels. Paper I deal with a new method of measuring moisture diffusivity at high moisture levels. Papers II to IV present methods of measuring moisture storage capacity as well as results from such measurements. Paper V evaluates the use of thermal imaging to measure transient moisture

The incidence of Diabetes Mellitus increases globally in epidemic proportions. Type 2 Diabetes is the most prevalent form of Diabetes, comprising 90% of the patients. In Type 2 Diabetes, two processes contribute to the development of the disease: insufficient insulin secretion from the pancreatic ?-cell and insulin resistance of the target organs. This leads to loss of control of blood glucose lev

Popular Abstract in Swedish Sammanfattning Teknik är alltid skapad för en förväntad brukare i ett antaget sammanhang. Inom kommersiell luftfart är dessa antaganden när det gäller design tydliga. Såväl besättning som utrustning är certifierad för en viss typ av operationer i enlighet med flygplanets drifthandbok. Trots denna genomtänkta definition av användare i sitt sammanhang händer det ändå attAbstract Technology is always designed for an assumed user in an assumed context. In commercial aviation, these design assumptions are clearly spelt out in that both crew and equipment are certificated for a specific operation as stated in the aircraft flight manual. Despite this well defined user context, the designed-for and the real contexts often differ enough so that adaptations of working p

The design and analysis of specular radar absorbing materials are investigated throughout the dissertation. Although the topic has been investigated for more than 60 years by many researchers and numerous designs have been proposed, still many technical challenges are remained unanswered. The basic questions are, e.g., the optimal thickness of a design, the possibility of utilization of unconventi

Surface display in insect cells: Systems available for surface display that utilize bacterial phages are insufficient for displaying a number of eukaryotic proteins. By instead presenting proteins on the surface of eukaryotic cells or virus, some of these problems might be overcome. The baculovirus/insect cell system, which has a high expression rate and post-translational mashinery closely resemb

Popular Abstract in Swedish Proteiner är helt nödvändiga för alla former av liv på jorden. En typisk cell består till 50-60 % av proteiner, om man bortser från vatten. Det är ett protein, hemoglobin, som transporterar syre från lungorna till kroppens celler och ger blodet dess röda färg. Det är ett protein, alfa- keratin, som bygger upp vårt hår och våra naglar. Det är två proteiner, aktin och myoProtein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. Protein S has previously been shown to contain four binding sites with high affinities for Ca²⁺ (K_a>9x10⁵ M^-1 at physiological ionic strength) and at least one of the sites h

A youth care institution may seem like a sort of regulated home. It does not resemble a home in the sense of a private household, and the youth living there usually do not define it as a home, but it seems like a home in the sense of being a place where youth in treatment spend most of their days and nights. But is that what a home is? In many cases, people in modern societies are not supposed to

Popular Abstract in Swedish Njurarnas huvudsakliga funktion i kroppen är att rena blodet från slaggprodukter och reglera vätskebalansen. Hos patienter med nedsatt njurfunktion måste blodet renas på alternativa sätt. Antingen leds blodet ut via slangar till en maskin som renar blodet (hemodialys), eller används bukdialys, så kallad peritoneal dialys (PD). Vid PD häller patienten dialysvätska i bukhIn the present thesis, the quantitative role of active transport (transcytosis) in bulk transvascular protein movement in vivo was evaluated. Using chemical transcytosis inhibition (N-ethylmaleimide (NEM) and filipin), we were able to show that NEM actually increases endothelial permeability to macromolecules, probably as a result of unspecific toxic action on endothelial cells. Filipin, on the ot

The major uncertainty in predicting the influence of human activities on global climate change is the effect of aerosols. Two physical properties of aerosols largely controlling their influence on climate are the particle number size distribution and the interaction of the particles with the surrounding water vapor. The work presented in this thesis provides new information on the interaction bet