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Poor metabolic control, early age at onset, and marginal folate deficiency are associated with increasing levels of plasma homocysteine in insulin-dependent diabetes mellitus. A five-year follow-up study

In a previous study, we showed that diabetic patients exhibited significantly increased concentrations of total plasma homocysteine (tHcy), but not until the onset of nephropathy. It was suggested that the hyperhomocysteinaemia might contribute to the accelerated atherosclerotic process in diabetic patients. In the present study, we have analysed the main determinants of plasma homocysteine (i.e.

The Cavitation Phenomenon: A Literature Survey

The meaning of the word cavitation is not known or understandable for many people. The definition which is commonly known about such phenomena is that the formation of cavities or bubbles is encouraged by a pressure change in the surroundings. However, cavitation is much more complex. A large amount of research work and studies on the dynamics of the cavitation phenomenon via numerical investigati

Investigating the development of creativity : The Sahlin hypothesis

How should the development of creativity be approached? Many accounts of children’s creativity focus on the relation between creativity and pretend play, placing make-believe and the mental exploration of possible scenarios about the world at the fore. Often divergent thinking and story-telling are used to measure creativity with fluency, originality, and flexibility as indicators. I will argue th

Low power multi-band CMOS receiver front-end

A Multi-band CMOS front-end was designed and fabricated in a 0.13μm CMOS process. The front-end employs a common-gate low noise amplifier (LNA) with capacitive cross coupling (CCC) technique and a double balanced mixer. The band selection is performed by switching capacitors in and out of the LNA load, changing the resonance frequencies ranging from 2.5GHz to 4.5GHz in 16 different frequency bands

Role of Wnt-5a in breast cancer

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos västerländska kvinnor. I Sverige kommer var tionde kvinna att drabbas av bröstcancer, vilket motsvarar drygt 5000 kvinnor om året. Dödligheten i bröstcancer är 30%. Detta innebär att en tredjedel av de som drabbas kommer att dö av sin sjukdom. Det är dock inte själva tumören i bröstet som dödar eftersom denna i princip alltBreast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. Wnts are a family of genes that have been implicated in many human tumours, so far mainly studied in colorectal cancer where activated Wnt signalling occurs in a vast majority of tumours. Wh

In Search of Caravans Lost . Iranian Intellectuals and Nationalist Discourse in the Inter-War Years.

This dissertation examines the characteristics of Iranian nationalist discourse between the World Wars. By looking at texts of intellectuals, men and women, published in three journals (Iranshahr, Name-ye Farangestan, and Ayandeh) in the 1920s this study maps the content of nationalist discourse and to what extent this discourse allows for dissonance. Informed by the work of Reinhart Koselleck (co

Combined eyetracking and keystroke-logging methods for studying cognitive processes in text production.

Writers typically spend a certain proportion of time looking back over the text that they have written. This is likely to serve a number of different functions, which are currently poorly understood. In this article, we present two systems, ScriptLog+ TimeLine and EyeWrite, that adopt different and complementary approaches to exploring this activity by collecting and analyzing combined eye movemen

Differential effects of LPS from Escherichia coli and Porphyromonas gingivalis on IL-6 production in human periodontal ligament cells.

Abstract Objective. Periodontal ligament (PDL) cells produce IL-6 upon stimulation with inflammation promoters, but the signaling pathways involved have not been characterized. This study investigates underlying mechanisms behind regulation of PDL cell IL-6 production by E. coli and P. gingivalis LPS. Materials and methods: Human PDL cells, endothelial cells and monocytes were stimulated with E. c

Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: Results from the EPIC-EURGAST study

MicroRNAs (miRNAs) are post-transcriptional gene regulators involved in a wide range of biological processes including tumorigenesis. Deregulation of miRNA pathways has been associated with cancer but the contribution of their genetic variability to this disorder is poorly known. We analyzed the genetic association of gastric cancer (GC) and its anatomical and histological subtypes, with 133 singl

The (in-) validity of the WSSUS assumption in vehicular radio channels

The assumption of wide-sense-stationarity (WSS) and uncorrelated scattering (US) of wireless propagation channels is widespread for the design and analysis of wireless propagation channels. However, the assumption is only valid within a limited range. In this paper, we investigate the extension of this range not only in time (WSS), but also in frequency (US), for measured vehicular propagation cha

Crisis, austerity and opposition in mainstream media discourses of Greece

This article analyzes neoliberal articulations of the economic crisis in Greece, as they appear at the Ekathimerini daily. Neoliberalism is primarily understood as the ideology organizing the political strategies of late capitalist production. The analysis focuses on the ways the capitalist crisis is presented in the context of Greece, as well as the ways that socio-political opposition to neolibe

Improving the Performance of OTDOA based Positioning in NB-IoT Systems

In this paper, we consider positioning with observed-time-difference-of-arrival (OTDOA) for a device deployed in long-term-evolution (LTE) based narrow-band Internet-of-things (NB-IoT) systems. We propose an iterative expectation- maximization based successive interference cancellation (EM-SIC) algorithm to jointly consider estimations of residual frequency- offset (FO), fading-channel taps and ti

Effects of the mainstream turbulence intensity and slot injection angle on the endwall cooling and phantom cooling of the vane suction side surface

In order to obtain better performance, gas turbines always operate with high inlet temperature. This contributes to a high level of thermal load on the first stage vane endwall. To ensure safe operation of a gas turbine within a proper temperature range, the cooling performance of the vane endwall must be further investigated. In the present study, effects of the mainstream turbulence and upstream

Two-dimensional action spectroscopy of excitonic systems : Explicit simulation using a phase-modulation technique

Two-dimensional (2D) spectroscopy has been intensively used to study electronic and vibronic coherences in biological systems and semiconductors. This technique studies coherent as well as incoherent signals that arise from the nonlinear interaction of a sequence of laser pulses. In this paper we present a direct evaluation of the 2D signal based on elementary quantum kinetics in order to compare

Targeted by Persuasion: Military Uniform and the Legal Matter of Killing in War

In this paper, we argue that the legitimation of killing in war is not simply formed by adherence to certain legal requirements that exist apart from and prior to war; instead, we suggest, the law of armed conflict in itself cannot but operate through admitting certain materials onto the battlefield as distinctively legal materials. Using the theory of legal materiality, we show that the military

Labeling plasmin with technetium-99m for scintigraphic localization of thrombi

A detailed study has been made of the method for labeling plasmin (NOVO Indstri A/S Denmark) with 99mTc in order to prepare a radioactive indicator for early scintigraphic visualization of thrombi and tumors. The best method found for preparing 99mTc-plasmic involved the reduction of 2.5 ml 99mTc-pertechnetate solution with 0.5 ml of 4 mM SnCl2, 2 M NaCl and 70 mM HCl. This mixture was then added

MADSTRESS: A linear approach for evaluating scattering and absorption coefficients of samples measured using time-resolved spectroscopy in reflection

Time-resolved spectroscopy is a powerful technique permitting the separation of the scattering properties from the chemical absorption properties of a sample. The reduced scattering coefficient and the absorption coefficient are usually obtained by fitting diffusion or Monte Carlo models to the measured data using numerical optimization techniques. However, these methods do not take the spectral d

Free radical degradation of hydroxyethyl cellulose

The degradation of hydroxyethyl cellulose (HEC) using sodium persulfate (NaPS) as free radical generator was studied at 60, 70 and 80 degrees C with different NaPS/HEC ratios. During the degradation reaction samples were withdrawn at regular intervals. The amount of persulfate remaining was analyzed by titration and the evolution of the HEC molecular weight distribution and viscosity was followed

Integrated selective enrichment target - a microtechnology platform for matrix-assisted laser desorption/ionization-mass spectrometry applied on protein biomarkers in prostate diseases

The performance of a miniaturized sample processing platform for matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS), manufactured by silicon microfabrication, called integrated selective enrichment target (ISET) technology was evaluated in a biological context. The ISET serves as both sample treatment device and MALDI-MS target, and contains an array of 96 perforated nanovial

A new multifunctional platform based on high-aspect ratio interdigitated NEMS structures

A multifunctional NEMS platform based on a mass-producible, surface relief grating has been developed and fabricated directly in polymer materials. The pattern consists of high aspect ratio interdigitated nanometer-sized pairs of walls and can be produced in a low-complexity one-step patterning process with nanoimprint lithography. In this paper, we demonstrate the usefulness of the platform prima