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The ability to design and tailor-make antibodies to meet the biophysical demands required by the vast range of current and future antibody-based applications within biotechnology and biomedicine will be essential. In this proof-of-concept study, we have for the first time tailored human recombinant scFv antibodies for site-specific photocoupling through the use of an unnatural amino acid (UAA) and
Timber structures and wooden element are in general affected by moisture and moisture variation in different ways. Their hygroscopic properties result in adsorption of water when wetted and in desorption when dried. Because the volume of wood is not constant but varies with the moisture content, uneven distribution of moisture will result in induced eigen-stresses because of internal restraint hyg
Until recently, the testing of ODE/DAE software has been limited to simple comparisons and benchmarking. The process of developing software from a mathematically specified method is complex: it entails constructing control structures and objectives, selecting iterative methods and termination criteria, choosing norms and many more decisions. Most software constructors have taken a heuristic approa
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and basal ganglia, the nature of the reciprocal interactions between these three brain regions remains unclear. This consensus paper gathers diverse recent views on a variety of important roles played by the cerebellum within the cerebello-basal ganglia-thalamo-cortical system across a range of motor and cogniti
In order to simplify computational methods based on dynamic programming, an approximative procedure based on upper and lower bounds of the optimal cost was recently introduced. The convergence properties of this procedure are analyzed in this paper. In particular, it is shown that the computational effort in finding an approximately optimal control law by relaxed value iteration is related to the
Supply chains are difficult to plan because they involve complex relationships that influence supply chain performance. In this paper, discrete-event simulation (DES) is discussed in order to identify if it could be a technique used to improve supply chain planning. Two DES models have been developed and are used in this paper to find out whether DES could be a technique for unraveling the complex
Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a
The aim of the present study was to enhance our understanding of vegetables as living organisms, interacting dynamically with the environment, and to explore the possible influence of metabolic changes on subsequent processing operations. Growing conditions, harvesting and handling in the packing house and storage conditions are key events leading to a defined “physiological status” of the vegetab
Popular Abstract in Swedish Nu levande fåglar delas traditionellt in i två grupper. Den ena gruppen är Palaeognathae och omfattar ratiter (struts, nandu etc.) och stubbstjärthöns. Den andra gruppen, Neognathae, representerar alla övriga fåglar, drygt 20 ordningar med över 9.000 arter. Grunden för denna uppdelning utgörs i första hand av morfologiska studier av fåglarnas gommar. Man har ansett att The Class Aves (birds) is generally divided into two main groups - the Palaeognathae and the Neognathae. Paleognathous birds are the flightless ratites and the tinamous, while Neognathae include all other extant birds (more than 9,000 species). This opinion has prevailed for more than a century and is primarily based on morphological studies of the avian bony palate. In this study, the relationsh
Christopher Polhem (1661-1751), called the father of Swedish mechanics, is the most famous figure in Swedish history of technology and our nation's foremost inventor ever. Remarkably enough, a close survey in a monograph has never been written on this inventor who in many ways initiated the technical and industrial development of Sweden. In this project will Polhem for the first time get a broad a
The extraction of spectral information in the inversion process of time-domain (TD) induced polarization (IP) data is changing the use of the TDIP method. Data interpretation is evolving from a qualitative description of the subsurface, able only to discriminate the presence of contrasts in chargeability parameters, towards a quantitative analysis of the investigated media, which allows for detail
Electron beam optics (particle betatron motion) and trajectory (centroid secular motion) in the FERMI@Elettra free electron laser (FEL) are modeled and experimentally controlled by means of the ELEGANT particle tracking code. This powerful tool, well known to the accelerator community, is here for the first time fully integrated into the Tango-server based high level software of an FEL facility, t
Purpose - To provide an integrated perspective to similarities and differences between approaches to automated classification in different research communities (machine learning, information retrieval and library science), and point to problems with the approaches and automated classification as such. Design/methodology/approach - A range of works dealing with automated classification of full-text
Både i Sverige och utomlands finns det ett behov av tvistlösning som alternativ till domstolsprövning. I Sverige har sedan 1917 Stockholms Handelskammares Skiljedomsinstitut fungerat som institut för alternativ tvistlösning genom skiljeförfarande och en gångbar lagstiftning på området har i Sverige funnits sedan 1929. Skiljeförfarandet som tvistlösningssätt präglas av fyra essentiella hörnstenar -In Sweden as well as in other countries, there is a need for alternative dispute resolution as supposed to dispute resolution through a court of law. The Stockholm Chamber of Commerce has functioned as an institute for alternative dispute resolution by arbitration since 1917, whereas passable regulations on arbitration have been in force since 1929. The arbitration as a method of dispute resolutio
Author: Erika Kalliokulju and Jane Stensson Titel: Integration coaches work concerning asylum seeking children Supervisor: Johan Cronehed Assessorer: The aim of this study is to examine how Helsingborg, a town in Sweden, works with integration of unaccompanied asylum seeking children regarding a temporary home for refugee children and how integration of children which have received asylum is perfo
In the ever evolving and ambiguous environment of VAT treatment of sales of shares, the underlying purpose test has arisen as a new form of controversy. While it seems to be a viable method for establishing in specific circumstances a strong enough direct and immediate link to guarantee deduction also for costs incurred in relation to an exempt or out-of-scope share disposal, the test’s nature and
The separation of hemicelluloses, like glactoglucomannans, from lignocellulosic process streams is an important step in building profitable lignocellulosic biorefineries. The most common method for the separation is membrane filtration, however, it has the draw-back of being sensitive to membrane fouling. To better understand the fouling process, it is desirable to be able to model the adsorption
Unga lagöverträdare har sedan länge särbehandlats i det svenska påföljdssystemet. Den som begår brott innan 21 års ålder särbehandlas idag både beträffande straffmätningen och påföljdsvalet. Bland annat får den unge lagöverträdaren sitt straff reducerat genom den så kallade straffrabatten. I december 2018 utkom ungdomsreduktionsutredningen med ett förslag om slopad straffrabatt för unga lagöverträYoung offenders have long been treated differently than adult offenders in the Swedish penal system. Anyone who commits crimes before the age of 21 is today treated differently both in terms of the sentencing measure and the choice of penalty. Among other things, the young offenders gets their sentence reduced by the so-called “penalty discount”. In December of 2018 a government department issued
Autenticitet ses av vissa forskare som en central del av välbefinnande. Mot bakgrund av detta ville vi fördjupa förståelsen för upplevelsen av autenticitet hos svenska gymnasieungdomar. Inom ramen för projektet “Välbefinnande och självkänsla på gymnasiet” på Lunds universitet genomförde vi semistrukturerade djupintervjuer med sju ungdomar i årskurs tre på gymnasiet om deras erfarenheter av att må Authenticity is viewed by some researchers as a central aspect of well-being. Considering this, we aimed to deepen the understanding of the experience of authenticity among Swedish high-school youths. As part of the research project ”Well-being and self-esteem in high school” at Lund university, we conducted seven semi-structured in-depth interviews with third year high school students about their
