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Purpose: The purpose of this work was to evaluate the visibility of simulated lesions in 2D digital mammography (DM) and breast tomosynthesis (BT) images of patients. Methods: Images of the same women were acquired on both a DM system (Mammomat Novation, Siemens Healthcare, Erlangen, Germany) and a BT prototype system adapted from the same type of DM system. Using the geometrical properties of the
Objective To compare drug survival on adalimumab, etanercept and infliximab in patients with rheumatoid arthritis (RA). Methods Patients with RA (n=9139; 76% women; mean age 56 years) starting their first tumour necrosis factor (TNF) inhibitor between 2003 and 2011 were identified in the Swedish Biologics Register (ARTIS). Data were collected through 31 December 2011. Drug survival over up to 5 ye
Objective To investigate the possible association of the BANK1 gene with genetic susceptibility to systemic sclerosis (SSc) and its subphenotypes. Methods A large multicentre case-control association study including 2380 patients with SSc and 3270 healthy controls from six independent case-control sets of Caucasian ancestry ( American, Spanish, Dutch, German, Swedish and Italian) was conducted. Th
The objectives of this master’s thesis were carried out for, and in cooperation with, a medical company. The goal was to assist in the development of a new product suited for organ transplantation. The product has several purposes including: helping to increase the proportion of organs suitable for transplantation, improving transplantation procedures, and increasing the length of time between org
The rise in prevalence and severity of obesity and related diseases imposes increasing costs on society. The objective of this thesis is to discuss and estimate the possible effects of a so-called fat tax as a tool for minimizing these costs. Two alternatives for differentiation of the value-added tax (VAT) on food are compared. The first alternative is an increase of the VAT levied on food contai
The latest Cyrtograptus lundgreni graptolite Chron (Late Wenlock, middle Silurian) is characterized globally by the Mulde Event faunal extinctions and glacio-eustatic sea-level change. Only in the last decade has it been recognized as one of the most severe extinction events of the Silurian Period. A section spanning the Slite Group-Halla Formation boundary on the islet Ytterholmen off main Gotlan
This dissertation aims to contribute empirically and theoretically, to the field of Islamology and Religious Studies in general. It does so by investigating the possible relation between Israeli Muslim women’s choice of religious identification and their individual experiences in everyday life transitions. Many of these women are traveling daily from their hometowns or villages to the major cities
Background More than one in five patients who undergo treatment for breast cancer will develop breast cancer-related lymphedema (BCRL). BCRL can occur as a result of breast cancer surgery and/or radiation therapy. BCRL can negatively impact comfort, function, and quality of life (QoL). Manual lymphatic drainage (MLD), a type of hands-on therapy, is frequently used for BCRL and often as part of com
Background: Fibroblast growth factor 23 (FGF23) is the earliest marker of disturbed mineral metabolism as renal function decreases. Its serum levels are associated with mortality in dialysis patients, persons with chronic kidney disease (CKD) and prevalent cardiovascular disease (CVD), and it is associated with atherosclerosis, endothelial dysfunction and left ventricular hypertrophy in the genera
Objective The complex genetic aetiology underlying irritable bowel syndrome (IBS) needs to be assessed in large-scale genetic studies. Two independent IBS cohorts were genotyped to assess whether genetic variability in immune, neuronal and barrier integrity genes is associated with IBS. Design 384 single nucleotide polymorphisms (SNPs) covering 270 genes were genotyped in an exploratory cohort (93
Objectives The aim of this study was to confirm the influence of TNFSF4 polymorphisms on systemic sclerosis (SSc) susceptibility and phenotypic features. Methods A total of 8 European populations of Caucasian ancestry were included, comprising 3014 patients with SSc and 3125 healthy controls. Four genetic variants of TNFSF4 gene promoter (rs1234314, rs844644, rs844648 and rs12039904) were selected
When it comes to political representation, all over the world women almost always make up a minority of representatives in the legislative bodies. The Scandinavian countries in general and Sweden in particular have though been exceptions to this rule with, when compared to other countries, a rather high percentage of women in elected positions. This development took off in the seventies: during th
Kultur och värderingar är ett allt mer omdiskuterat område i urvalsprocesser samtidigt som egenskaper och kompetenser krävs för att en person ska betraktas som kvalificerad för en anställning. Valet av frågor och bedömningsunderlag ligger till grund för anställningsbeslut och är därför av stor betydelse i intervjusammanhang. I denna studie genomfördes en attitydmätning för att undersöka vad yrkesv
This bachelor project by Filip Charmolu is a project where a product series has been created for a brand, Design House Stockholm. Out of passion for building products for brands a product development process started where brand identity of Design House Stockholm became the starting point and led the way forward. External and internal information about the brand from different point of views
A Power Amplifier (PA) is an essential electronic component in all microwave and millimeter-wave applications and, more specifically, in any transmitting system where the level of input power signal needs amplification to the desired level.Linearity and high efficiency are of utmost importance in PAs. However, high-efficiency PAs tend to be non-linear, and PAs working in the linear region might ha
A variety of demand side management (DSM) methods are needed to ensure electric grid reliability and to integrate increasing shares of renewable energy sources into electricity networks. To investigate whether communal laundry rooms in Stockholm represent a good candidate for employing DSM to reduce the severity of electricity load peaks, tenants are surveyed on their willingness to temporarily lo
