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PURPOSE: Epinephrine is used in local anesthetics to induce vasoconstriction and thus reduce bleeding and prolong the anesthetic effect. Finding the optimal delay between the administration of the anesthetic and skin incision to ensure vasoconstriction and minimize bleeding is important and has recently become the subject of debate. This is the first study to assess blood perfusion and oxygen satu

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Krakus Mound, a pre-historic man-made hill in Krakow, provides a magnificent panorama of the city. The opposite direction opens up to a gravel pit named Kamieniołom Libana. Here, a Jewish entrepreneur, Bernard Liban, founded a company for the production of limestone and fertilizers in 1873. Later on, the plant was used as a Nazi labor camp. At the place where this camp was situated, the American fKrakus Mound, a pre-historic man-made hill in Krakow, provides a magnificent panorama of the city. The opposite direction opens up to a gravel pit named Kamieniołom Libana. Here, a Jewish entrepreneur, Bernard Liban, founded a company for the production of limestone and fertilizers in 1873. Later on, the plant was used as a Nazi labor camp. At the place where this camp was situated, the American f

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Management decisions in conservation of threatened species require trading off social needs against biodiversity values, including the prioritization of conservation locations, i.e. where conservation efforts should take place. To improve conservation decisions for the thick-shelled river mussel, Unio crassus, a highly threatened temporary parasite on fish, we performed a field study on how mussel

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Leaching of dissolved organic carbon (DOC) from the forest floor and transport in soil solution into the mineral soil are important for carbon cycling in boreal forest ecosystems. We examined DOC concentrations in bulk deposition, throughfall and in soil solutions collected under the O and B horizons in three Norway spruce stands along a climatic gradient in Sweden. Mean annual temperature for the

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We have analyzed the content of N-unsubstituted glucosamine in heparan sulfate from glypican-1 synthesized by endothelial cells during inhibition of (a) intracellular progression by brefeldin A, (b) heparan sulfate degradation by suramin, and/or (c) endogenous nitrite formation. Glypican-1 from brefeldin A-treated cells carried heparan sulfate chains that were extensively degraded by nitrous acid

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Fitnesskulturen växte fram i USA och blomstrade under 1970-talet men har sedan dess spridit sig över hela världen. Idag hålls tävlingar och evenemang inom fitness i Sverige och fitnessbranschen växer sig större. Användningen av dopingpreparat förekommer i alla sporter och även inom fitnessbranschen. Den tidigare forskningen visar på studier som tar upp dopingpreparat som problem men i kontexten fi

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Environmental pollution caused by human activity is one of today's biggest dilemmas. Pollution in air, water and soil can pose risks to human health and the environment and can lead to a reduction in available resources. Investigating and remediating contaminated areas is therefore an important task. In the past 20 years, there have been two major spills of gasoline and diesel at the Energy Po

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Agricultural management and vegetation complexity affect arthropod diversity and may alter trophic interactions between predators and their prey. Web-building spiders are abundant generalist predators and important natural enemies of pests. We analyzed how management intensity (tillage, cutting of the vegetation, grazing by cattle, and synthetic and organic inputs) and vegetation complexity (plant

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Utsläpp från jordbruk och förbränning av fossila bränslen ökar den atmosfäriska belastningen av reaktivt kväve (N). Kvävenedfall beräknas fortsätta utgöra betydande skada både för miljön och människors hälsa under de kommande decennierna. Övergödning som resultat av kväveläckage är en av de negativa effekterna av nedfallet. Den inträffar när tillförseln av N in i ett ekosystem överstiger upptagninEmissions from agriculture and the combustion of fossil fuels increase the atmospheric load of reactive nitrogen (N). N deposition is projected to continue posing significant harm both for environmental and human health over the upcoming decades. Eutrophication as a result of N leaching is one of the negative effects of heavy deposition. It occurs when the input of N into an ecosystem exceeds its

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I had the opportunity to work with the flood plain community: Nossa Senhora das Gracas in the Amazon in Brazil. During a month long stay I observed the daily life of the people. A life where the inhabitants shape their daily routines after the rising and dropping Solemoes river. Solemoes is a part of the Amazon river. I identified a need of harvesting water during the low water season, when the r

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I takt med att världens befolkning ökar och allt fler väljer att bosätta sig inne i staden ökar behovet av att hitta smarta och hållbara sätt att förtäta. En stad har sina begränsningar och därför har det genomgående i projektet varit viktigt att undersöka hur vi kan töja på stadens gränser och tillföra nya värden utan att tumma på befintliga kvaliteter. Att förtäta en stad är en möjlighet att höjAs the world population increases and more people choose to settle in the city the need to find smart and sustainable solutions to densify increases. A city has limitations and therefore it has been important to look at how we can stretch the city´s borders and adding new values without compromising the existing qualities. To densify a city is an opportunity to improve existing urban spaces and in

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The topic of this study is the phosphorylation dependent interaction between aquaporin 2 (AQP2) and the FERM domain of ezrin. AQP2 is an important water channel for finetuning the water content of the urine based on the needs of the body. The main way of regulating how much water is reabsorbed is by regulating the amount of AQP2 present in the apical membrane. This regulation is controlled throug

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DERA, 2-deoxyribose-5-phosphate aldolase, catalyzes the retro-aldol cleavage of 2-deoxy-ribose-5-phosphate (dR5P) into glyceraldehyde-3-phosphate (G3P) and acetaldehyde in a branch of the pentose phosphate pathway. In addition to the physiological reaction, DERA also catalyzes the reverse addition reaction and, hence, is an interesting candidate for bio-catalysis of carbo-ligation reactions, which