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Osteoarthritis of the metacarpo/metatarsophalangeal joints is one of the major causes of poor performance in horses. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) may be a useful technique for noninvasively quantifying articular cartilage damage in horses. The purpose of this study was to describe dGEMRIC characteristics of the distal metacarpus3/metatarsus3 (Mc3/Mt

The aim of this literature study was to answer whether the thermal impact of geothermal energy systems pose a potential environmental risk to groundwater quality and microorganisms in the sub surface and to above ground vegetation. This study shows that the thermal impact of high temperature systems operating with temperatures ≥25⁰C in groundwater could lead to adverse effects on groundwater chemi

Frågan om dödshjälp är en pågående diskussion världen över. I Sverige är assisterat självmord inte straffbart. Eutanasi är däremot förbjudet och bedöms enligt 3 kap 2 § BrB. Denna uppsats syftar till att redogöra för den rättsliga gränsdragningen mellan assisterat självmord och eutanasi samt att analysera denna gränsdragning med hjälp av legalitetsprincipen. Rättsläget presenteras med hjälp av denThe issue of mercy killing is an ongoing discussion worldwide. In Sweden, assisted suicide is not punishable. Euthanasia, on the other hand, is prohibited and judged according to chapter 3 § 2 of the Swedish penal code. This essay aims to account for the legal demarcation between assisted suicide and eutha-nasia and to analyze this demarcation with the help of the principle of legality. The legal

We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range similar to 1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. We focused on characterizing the spatial and temporal variation of new particle formation events and relevant particle formation parameters across Europe. Dif

Understanding the relationship between photosynthesis, net primary productivity and growth in forest ecosystems is key to understanding how these ecosystems will respond to global anthropogenic change, yet the linkages among these components are rarely explored in detail. We provide the first comprehensive description of the productivity, respiration and carbon allocation of contrasting lowland Am

The platelet-derived growth factor (PDGF) ß receptor mediates mitogenic and chemotactic signals. Like other tyrosine kinase receptors, the PDGF ß receptor is negatively regulated by protein tyrosine phosphatases (PTPs). To explore whether T-cell PTP (TC-PTP) negatively regulates the PDGF ß receptor, we compared PDGF ß receptor tyrosine phosphorylation in wild-type and TC-PTP knockout (ko) mouse em

Populärvetenskaplig sammanfattning: Mer än två miljarder människor, mestadels i utvecklingsländer, saknar tillgång till moderna energikällor eller elektricitet. Behovet av rena, effektiva, pålitliga och ekonomiskt överkomliga energitjänster är en viktig fråga i utvecklingsländer, särskilt för landsbygden, där merparten av befolkningen bor. Förnyelsebara energikällor i form av småskaliga vattenkrafOver 2 billion people, mostly in developing countries, have no access to modern fuels or electricity. The necessity of clean, efficient, reliable and affordable energy services is a crucial issue in developing countries, especially in the context of rural areas where the majority of the people lives. Renewable energy sources in shape of small-scale hydropower systems are a complement or alternativ

It is essential to gain knowledge about the causes and extent of migratory connectivity between stationary periods of migrants to further the understanding of processes affecting populations, and to allow efficient implementation of conservation efforts throughout the annual cycle. Avian migrants likely use optimal routes with respect to mode of locomotion, orientation and migration strategy, infl

Although particulate organic and elemental carbon (OC and EC) are important constituents of the suspended atmospheric particulate matter (PM), measurements of OC and EC are much less common and more uncertain than measurements of e.g. the ionic components of PM. In the framework of atmospheric research infrastructures supported by the European Union, actions have been undertaken to determine and m

Proteolytic activation is a unique feature of the epithelial sodium channel (ENaC). However, the underlying molecular mechanisms and the physiologically relevant proteases remain to be identified. The serine protease trypsin I can activate ENaC in vitro but is unlikely to be the physiologically relevant activating protease in ENaC-expressing tissues in vivo. Herein, we investigated whether human t

Poster A153Introduction: Diabetic peripheral neuropathy (DPN) is a devastating complication to DM, potentially leading to diabetic foot ulcers. Studies using electrophysiology shows high occurrence of subclinical DPN among children, but it is unclear when and how to start screen children with T1D for DPN. Aim: To investigate whether evaluation of the vibrotactile sense, using a multi-frequency method, in the

Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus, additional tissue-derived signals, such as danger-associated molecular patterns (DAMPs), are indispensable for manifestation of local inflammation. S100A8/S100A9 complexes are the most abundant DAMPs in many autoimmune diseases. However, regula