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Surrogate measures of safety : Site-based observations

Traditionally, traffic safety is expressed through the number of accidents (crashes) or people injured, since these are the most direct manifestations of an unsafe traffic environment. As we discuss in this chapter, such an approach has its limitations due to the low frequency of accidents and some other issues. Neither is it unusual that accident data is not available, not reliable or lacks impor

Optimal departure decisions of songbirds from an experimental stopover site and the significance of weather

Recent models have worked with the assumption that birds try to minimize either time, energy or predation risk during migration, or some combination of these. The few empirical studies available have suggested that time minimization may be the most common strategy. One way of distinguishing between strategies is to study the departure decisions of migrating birds. We supplied migrating European ro

Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases

A series of azapeptides as potential inhibitors of cysteine proteases were synthesized. Their structures, based on the binding center of cystatins, contain an azaglycine residue (Agly) in place of the evolutionarily conserved glycine residue in the N-terminal part of the enzyme binding region of cystatins. Incorporation of Agly should lead to deactivation of the acyl-enzyme complex formed against

Tenocyte response to cyclical strain and transforming growth factor beta is dependent upon age and site of origin

The effect of strain and transforming growth factor beta on equine tendon fibroblasts (tenocytes) was assessed in vitro. Tenocytes were isolated from flexor and extensor tendons of horses from foetal to 10 years of age. These cells were cultured until confluent on collagen-coated silicone dishes. Cyclic biaxial strain of 9 +/- 1% was applied at 0.5 Hz for 24 hours with or without added TGFbeta1 or

Interpreting canopy development and physiology using a European phenology camera network at flux sites

Plant phenological development is orchestrated through subtle changes in photoperiod, temperature, soil moisture and nutrient availability. Presently, the exact timing of plant development stages and their response to climate and management practices are crudely represented in land surface models. As visual observations of phenology are laborious, there is a need to supplement long-term observatio

IL-23 to see : Gut DCs shine bright in inductive sites

The cytokine IL-23 plays important roles in intestinal barrier protection and integrity, but is also linked to chronic inflammation. In this issue of JEM, Ohara et al. (https://doi.org/10.1084/jem.20230923) provide clarity on the much-debated question of which cells produce IL-23.

Critical Step in the HCl Oxidation Reaction over Single-Crystalline CeO2-x(111) : Peroxo-Induced Site Change of Strongly Adsorbed Surface Chlorine

The catalytic oxidation of HCl by molecular oxygen (Deacon process) over ceria allows the recovery of molecular chlorine from the omnipresent HCl waste produced in various industrial processes. In previous density functional theory (DFT) model-calculations by Amrute et al. [ J. Catal. 2012, 286, 287−297.], it was proposed that the most critical reaction step in this process is the displacement of

The Biography of a Fragment : A Late Mesolithic Antler Object from the Strandvägen Site, South Central Sweden

When investigating a settlement dated to the late Mesolithic,c.5500 cal BC, at Strandvägen in south-central Sweden, an extensive assemblageof implements made of bone and antler was found. Among these finds was a richlydecorated antler piece, likely part of an antler axe. Originally it was equippedwith shallow ornamentation that was later removed and replaced by a seconddeeper motif of longitudinal

Body composition and migration strategies : a comparison between robins (Erithacus rubecula) from two stop-over sites in Sweden

Robins captured as passage migrants by the Baltic Sea in Sweden at Falsterbo and Ottenby Bird Observatories, respectively, differ with respect to body mass, fat load and orientation behaviour. Relatively more birds with large visual fat deposits are captured at Ottenby than at Falsterbo, but robins at Falsterbo carry more fat than robins at Ottenby. Robins with small fat loads at Ottenby probably

Integrated assessment of soil chemical status. 2. Application of a regionalised model to 622 forested sites in Switzerland.

A model, MAKEDEP, was developed for reconstructing historic atmospheric deposition and nutrient uptake for forests using present day values. Deposition is reconstructed by separation of wet deposition and throughfall into five different categories. Dry deposition is assumed to depend linearly on needle biomass. Non-marine deposition is scaled using general European emission and deposition trends f

Use of the 24-lead "standard" electrocardiogram to identify the site of acute coronary occlusion

This review presents the added value for diagnosis of acute ischemia/infarction of considering ST elevation in the 12 inverted leads (-I, -II, -II, -aVR, etc) of the standard electrocardiogram in addition to ST elevation in 12 positive leads. A small number of studies have been published showing substantial increases in sensitivity at the "cost of' slight decreases in specificity. One recent study

De-bordering and re-bordering practices at the intersection of gender and migration. A multi-site exploration of specialized services for migrant women experiencing violence in Italy and Sweden

This study builds on analyses of everyday professional practices to explore de-bordering and re-bordering processes in the field of gender-based violence (GBV). The concepts of de-bordering and re-bordering practices express the tensions arising from the conflictual roles taken on by civil society actors (CSAs) in their double vest of service delivery for the state and advocate for migrant women w

Optimotaxis: A Stochastic Multi-agent on Site Optimization Procedure

We consider the problem of seeking the maximum of a scalar signal using a swarm of autonomous vehicles equipped with sensors that can take point measurements of the signal. Vehicles are not able to measure their current position or to communicate with each other. Our approach induces the vehicles to perform a biased random walk inspired by bacterial chemotaxis and controlled by a stochastic hybrid

Potential Risk Handling Alternatives for Supply Chain Disruptions in Liquid Food Production – the case of V&S Vin & Sprit AB, the Sundsvall site

V&S Sundsvall (a part of V&S Vin & Sprit AB) is a Swedish company producing different alcoholic beverages, mainly for the Swedish market. The company has lately paid increasing attention to supply chain disruption risk issues. In another study, one of the authors (Paulsson 2007) developed a model, called the DRISC (Disruption Risks In Supply Chains) model, for the structuring, evaluati

A Search for Neonicotinoid Binding Sites in the Optic Lobes of Honeybees and Blowflies

Neonicotinoid insecticides are agonists to nicotinic acetylcholine receptors (nAChRs) in the brains of insects. At sub-lethal doses these chemicals cause behavioral abnormalities in several bee species, reducing overall fitness. nAChRs expressed in the optic lobes of insects bind neonicotinoids, thus may be involved in these behavioral changes. Here we attempted without success to visualize the pr