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Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo
Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r
https://www.energy.lth.se/research/energy-storage-conversion - 2026-07-07
Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient
Bookshops are one of the most visible places for books in public space. No bookshop can ever offer every book available; rather it is in its selection that each bookshop is unique. Value, writes Michael Bhaskar in Curation (2016), no longer resides in access, but in curation—in selecting and arranging. The article argues that curating practices in bookshops can be mapped from four main aspects: sp
Going on exchange studies means that you spend part of your programme at a partner university linked to Malmö Academy of Music or Lund University. Who can apply for exchange studies?Anyone studying on a programme at Malmö Academy of Music can apply for exchange studies as long as you meet the eligibility requirements. As a programme student at the Academy of Music, you have fantastic opportunities
https://www.mhm.lu.se/internt/exchange-studies - 2026-07-07
Abstract To build airtight buildings is something that is becoming increasingly important for operators in the construction industry. As stricter demands on airtightness and lower energy consumption are required This airtight project addresses two aspects of the construction for the success of air sealing. Partly which methods to use to get a building airtight but also what utilities have been dev
We consider the following combinatorial two-player game: On the random tree arising from a branching process, each round one player (Breaker) deletes an edge and by that removes the descendant and all its progeny, while the other (Maker) fixates an edge to permanently secure it from deletion. Breaker has won once the tree's root is contained in a finite component, otherwise Maker wins by building
