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Tamoxifen (Tam) is widely used in chemotherapy of estrogen receptor-positive breast cancer. It inhibits proliferation and induces apoptosis of breast cancer cells by estrogen receptor-dependent modulation of gene expression, but recent reports have shown that Tam (especially at pharmacological concentrations) has also rapid nongenomic effects. Here we studied the mechanisms by which Tam exerts rap
Senior lecturer Contact details Email: matthias [dot] lehner [at] iiiee [dot] lu [dot] se Phone: +46 46 222 02 07Organisation The International Institute for Industrial Environmental Economics Service point: 53 WebpageMatthias Lehners profile in Lund University research portalOther affiliations Affiliated researcher Centre for Retail and Logistics (REAL) Health and safety representative The Intern
https://www.iiiee.lu.se/matthias-lehner - 2026-06-06
Språk- och litteraturcentrum Litteraturlista FLRA01, Modersmålsundervisning och studiehandledning, 60 högskolepoäng Fastställd av Sektion 3 2019-06-07, reviderad av Styrelsen för Sektion 5, 25-11-27 Delkurs 1: Introduktion till modersmålsundervisning och studiehandledning, 7.5 högskolepoäng Obligatorisk kurslitteratur Ahnborg, Marie-Hélène (2025). På språklig grund - Betänkande av Utredningen om i
https://www.sol.lu.se/media/utbildning/dokument/kurser/FLRA01/20261/FLRA01_Litteraturlista_VT26_1.pdf - 2026-06-07
Popular Abstract in Swedish Titeln på den här avhandlingen är ”Nukleinsyror som läkemedel och mål för läkemedel, med fokus på anticanceraktiva platinaföreningar och små interferande RNA”. Nukleinsyror är mer kända som sina förkortningar DNA och RNA. Anticanceraktiva platinaföreningar är en typ av läkemedel mot cancer. Små interfererande RNA är en slags reglermekanism för hur mycket av ett visst prTo ensure that patients receive a safe and effective treatment, it is important to understand how drugs interact with and affect molecules within a cell. Here, evaluation of platinum based drugs and their ability to interfere with nucleic acid functions is presented. The main focus of this thesis has been to evaluate whether siRNA efficiency can be modified by two clinically used anticancer active
Predation is a well-studied driver of ecological selection on prey traits, which frequently drives divergence in anti-predator performance across environments that vary in predation risk. However, predation also alters prey mortality regimes, where low predation risk often results in higher prey densities and consequently higher intensities of intraspecific resource competition. In addition, preda
Biofuel production in the world has grown exponentially, stimulated by public policies, in countries of the North as well as of the South, and has been seen as one of the main drivers behind the recent food price hike. Thus conflicts over land need to be factored in when biofuels are assessed. Nowhere in the world is biofuel production seen to be more successful – economically, ecologically – than
Optical diagnostics are remote non-intrusive sensing techniques. The thesis work concerns the use of OH and soot optical diagnostics for combustion research.Internal combustion (IC) engines are widely used for the generation of power and for transportation purposes. Soot emission, involving carbon particles that emanate from the combustion process, is one of major sources of pollutants in engine e
To determine whether health-related lifestyle factors are associated with attendance at a population-based invitational mammography screening program in southern Sweden, data on health-related lifestyle factors (smoking, alcohol use, physical activity, BMI, diet, self-rated health, and stress) were obtained from the Malmö Diet and Cancer Study and linked to the Malmö mammography register (Sweden,
The thesis includes five separate studies concerned mainly with psychosocial aspects of the problems that athletes afflicted with long-term sport injuries face. The first study deals with relationships between personality variables, coping strategies and mood-levels, both in athletes participating in competitive sports and in a non-athlete reference groups. The results indicate the athletes to us
Southernmost Patagonia, located at the relatively narrow passage between Antarctica and South America, is a highly sensitive region for recording meridional and zonal changes in the pattern of oceanic and atmospheric circulation. The island of Isla de los Estados, situated at 54.5 degrees S, 64 degrees W, east of Argentinean Tierra del Fuego, provides an exceptional possibility, to investigate ter
“The code that guides the Path” Geosmin is a volatile metabolite that smells like the earthy odorant that is mostly predominant after a heavy rain fall; what produces this intensive surge of geosmin in the air is from the spore producing family streptomycetaceae. Not only do these bacteria produce a scent that most people find pleasant to smell, they also play a key role in modern society. Why th
Previous studies has concentrated around the area of children living with parents who has a alcohol problem, hence less research has focused on the children when they have become adults and moved away from home. I contacted a Danish organization, named Tuba, which provides free therapy to people, in the ages from 14 to 35, where one or both parents have an alcohol problem. In collaboration with Tu
This qualitative case study analyses the Chilean NGO TECHO, now present in 19 countries in Latin America and the Caribbean, from the perspective of Foucault's concept of governmentality, as elaborated by Rose and Miller (2008). They argue that non-state modes of power are the defining features of contemporary societies, and that these operate through loose, associative networks through which a
Summary This thesis is a study which primary objective is to examine the court´s risk assessment in legal custody, and contact disputes when a child is at risk of being harmed. My thesis also includes an interdisciplinary perspective to give a more detailed understanding of the process – of which consequences it entails if authorities and courts don´t make reliable risk assessments. Physical, psyc
Den tilltalades tidigare brottslighet kan i svensk rätt påverka påföljdsbestämningen för ny brottslighet, dvs. straffmätning och påföljdsval, på främst tre sätt. I första hand kan den tidigare brottsligheten beaktas genom ett skärpt påföljdsval. I andra hand har rätten möjlighet att förklara villkorligt medgiven frihet förverkad. I sista hand finns det genom straffskärpning möjlighet att förlänga
Electrical and electronic equipment (EEE) causes serious environmental impact in its end-of-life phase and it is the largest known source of heavy metals and organic pollutants in municipal waste. Moreover, waste electrical and electronic equipment (WEEE) containes valuable components that if recycled and reused, could reduce the use of virgin materials. However, nowdays WEEE is mostly landfilled.
Abstract Individuals within species often show a consistent differences in their risk-taking behavior. I investigated whether intra-specific variation in risk-taking behavior is adaptive, i.e. if it stems from the life history strategy differences between individuals. As a result of life history trade-offs, individuals vary in their investment into survival and reproduction, such that some indivi
Executive Summary Title Business Models for Mobile Internet Authors Andersson Tobias, Talborn Henric, Weikert Magnus Directors Professor Allan T. Malm Ph D Candidate Magnus Wide Purpose How should mobile operators design their business models for mobile Internet in order to be successful? Method The method used in order to reach the purpose is structured in, theory, empirical and analysis around t
