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Introduction: Designing adjuvant trials is challenging because of uncertainties of prevalence and outcome of high-risk renal cell cancer (RCC) despite use of validated risk scores. Our objective is to investigate how differences in eligibility criteria may impact on potential study results in RCC adjuvant trials. Patients and Methods: RECUR is a multicenter European database capturing patient and
We have tried to calculate the free energy for the binding of six small ligands to two variants of the octa-acid deep cavitand host in the SAMPL5 blind challenge. We employed structures minimised with dispersion-corrected density-functional theory with small basis sets and energies were calculated using large basis sets. Solvation energies were calculated with continuum methods and thermostatistic
Abstract Objective. Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare clinical entity. The objective of this study was to review a single institution's experience with this uncommon tumor, as well as review the literature. Material and Methods. Consecutive patients, who underwent surgery for a pathologically confirmed SPN between 1991 and 2010, were retrospectively reviewed. A PubMed
Single-strand RNA-binding proteins (RBPs) are involved in many aspects of RNA metabolism and in the regulation of gene transcription. The RBP RBM3 was recently suggested to be a proto-oncogene in colorectal cancer; however, such a role has not been corroborated by previous studies in the colon or other tumor types, and the prognostic implications of tumor-specific RBM3 expression remain unclear. M
Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S
The growing demand to lower greenhouse gas emissions and transition from fossil fuels, has put methanol in the spotlight. Methanol can be produced from renewable sources and has the property of burning almost soot-free in compression ignition (CI) engines. Consequently, there has been a notable increase in research and development activities directed towards exploring methanol as a viable substitu
Micron-sized aluminum (Al) particles have recently been proposed as promising carbon-free energy carriers. To facilitate the application of micron-sized Al particles as fuel in practical energy generation system, this study experimentally investigates the underlying mechanisms of the ignition, stabilization and particle-particle collision in lifted Al particle cloud flames. High-resolution shadowg
Most often, the laminar burning velocity (SL) of ammonia was measured in mixtures diluted by nitrogen bearing in mind its potential use as an alternative carbon-free fuel. Replacing the diluent with argon can increase the flame temperature and thus provide additional targets for validating pertinent detailed kinetic models. The SL data for ammonia + oxygen + argon mixtures are scarce; therefore, i
Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC) cohort. During follow-up, we identif
While research in the field of technology is surging, research on older adults playing an active role in designing and developing smart home technology (SHT) to enhance usability and adoption is lacking. It is important to co-develop products with potential users to better match their needs and desires. This study aims to generate ideas about SHT that can enhance the use and adoption of SHT that c
Today cities across the world in different scales are struggling to achieve a sustainable living space where children are full of pride to call home. My thesis project inspired by my own journey of searching for a safe and inviting public space where I can spend my leisure time. I grew up in K.S.A, where for a long time I have experienced that women are not safe in a public space. Then I came to m
Uppsatsen syftar till att undersöka vad elever säger om de didaktiska aspekterna av Våga!. Våga! är ett utbildningskoncept där musikundervisning och sex- och samlevnadsundervisning möts. Konceptet består av tre delar; en humoristisk, pedagogisk musikföreställning om sex och samlevnad, ett samtal kring föreställningen och ett efterarbetesmaterial. Uppsatsen utgår från Arfwedsson och Arfwedssons (1This essay examines what pupils say about the didactical aspects of Våga! (The Swedish word ”didaktik” is to a large extent equivalent to ”curriculum research”. However, in the lack of an exact translation, the word ”didactics” is used in this abstract, knowing that that word has different connotations in English than in Swedish.) Våga! is an educational concept, in which music education and sexua
Bakgrund: Generellt bland industrivärldens lager är denhuvudsakliga uppgiften försörjning av material mot montering och tillverkning. Så är fallet även på ABB Swedewater. När en produkt ska tillverkas plockar personalen på lagret ihop de komponenter som behövs och skickar dem till tillverkningen. Materialet till anläggningen ”kittas” för att underlätta arbetet i produktion. Detta betonar vikten avBackground: Generally among industrialized warehouses, the main operational task is to supply the assembly or manufacturing with material, so is also the situation at ABB Swedewater. When manufacturing a product, the warehouse personnel pick necessary components requested by othersections of the production. This stresses the importance of a correct performance when picking, as this forms the base
Background and Objectives: Volunteering is characterised by an obligation-free action that occurs typically in an organisational setting. Its goals are to improve the health and well-being of others. Volunteering has the possibility of increasing both mental and physical health of volunteers. Values are the guiding motivators to applying for volunteering activities. The thesis aimed to understand
Problem/ background: Since the enlargement of the EU in 2004 and the free mobility directive there has been growing concern of homelessness and destituteness among EU migrants in several European countries, Sweden being one of them. This is an important welfare and policy issue. Previous research on this matter has tended to focus on challenges faced by, as well as strategies adopted by, NGOs and
This thesis aim to increase the understanding of educational divide in the urban environment. The study takes place in Malmö, in many ways a divided city and so even within the school system. Several political decisions were implemented in the early 90s in Sweden to make the educational system more equal and adjusted to individual needs of students. A free-choice of school, private- school-establi
Den ökade användningen av läkemedel och otillräcklig teknik i reningsverken har lett till allt större halter av läkemedel och andra organiska mikroföroreningar (OMF) i naturliga vatten. Detta har i sin tur konstaterats påverka exempelvis fiskars beteende och fortplantningsförmåga. OMF har även detekterats i det svenska dricksvattnet. På grund av detta har en satsning skett de senaste åren inom forThe increased use of pharmaceuticals in combination with inadequate techniques and procedures in the wastewater treatment plants (WWTPs) have resulted in higher concentrations of pharmaceuticals and other organic micro pollutants (OMPs) in the aquatic environment. It has been established that these pollutants have caused changes in the behaviour and reproduction of fishes. Furthermore, these OMPs
Authors: Rebecka Werngren and Sofia Ekblom Title: The last way out. A qualitative study of how social workers reach a motion about compulsory institutional care for youth. [translated title] Supervisor: Claes Levin The purpose of this study has been to examine social workers opinion about compulsory institutional care for youths. The aim has been to recognize how professionals reach decisions abo
Construction engineers involved in building design at an early stage is something I think should prevent errors later during the construction process. In my study I wanted to examine a construction engineer's ability to act as both an architect and engineer in an architectural competition. I wanted to participate in an architectural competition which is contemporary and focus on energy efficie
Development of valuable products from downstream process residual biomasses and profound reduction of waste are two key components for developing a more sustainable process industry. The importance of bio-renewable feedstocks and bio-based processing techniques are also crucial in the transformation to a more sustainable and green society. Therefore focus is directed on full exploitation of seawee
