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Association Between Physiological Significance and Vulnerable Plaque Characteristics in Patients With Myocardial Infarction : A Prospect II Substudy

Background: Hemodynamically obstructive coronary plaques may contain more vulnerable plaque characteristics than nonobstructive lesions. Objectives: The authors aimed to assess whether pressure-wire–based physiologic indices in nonculprit lesions are associated with vulnerable plaque characteristics. Methods: In the PROSPECT II study, patients with recent myocardial infarction underwent coronary a

Prospective Study of Chemotherapy in Combination with Cytokine-induced Killer Cells in Patients Suffering from Advanced Non-small Cell Lung Cancer

The present study evaluated the clinical efficacy of chemotherapy in combination with cytokine-induced killer (CIK) biotherapy compared to the chemotherapy alone. Fifty-nine advanced non-small cell lung cancer (NSCLC) patients were randomly divided into two groups, group A (chemotherapy, alone, including docetaxel 75 mg/m(2), day 1; cisplatin, 25 mg/m(2), days 1-4, tri-weekly) and group B (chemoth

Manipulating charge transfer excited state relaxation and spin crossover in iron coordination complexes with ligand substitution

Developing light-harvesting and photocatalytic molecules made with iron could provide a cost effective, scalable, and environmentally benign path for solar energy conversion. To date these developments have been limited by the sub-picosecond metal-to-ligand charge transfer (MLCT) electronic excited state lifetime of iron based complexes due to spin crossover-the extremely fast intersystem crossing

Binding free energies in the SAMPL5 octa-acid host–guest challenge calculated with DFT-D3 and CCSD(T)

We have tried to calculate the free energy for the binding of six small ligands to two variants of the octa-acid deep cavitand host in the SAMPL5 blind challenge. We employed structures minimised with dispersion-corrected density-functional theory with small basis sets and energies were calculated using large basis sets. Solvation energies were calculated with continuum methods and thermostatistic

Prevalence, Disease-free, and Overall Survival of Contemporary Patients With Renal Cell Carcinoma Eligible for Adjuvant Checkpoint Inhibitor Trials

Introduction: Designing adjuvant trials is challenging because of uncertainties of prevalence and outcome of high-risk renal cell cancer (RCC) despite use of validated risk scores. Our objective is to investigate how differences in eligibility criteria may impact on potential study results in RCC adjuvant trials. Patients and Methods: RECUR is a multicenter European database capturing patient and

Risk of second cancer in Hodgkin lymphoma survivors and influence of family history

Purpose: Although advances in Hodgkin lymphoma (HL) treatment have led to improved disease-free survival, this has been accompanied by an increased risk of second cancers. We sought to quantify the second cancer risks and to investigate the impact of family history. Patients and Methods: Using the Swedish Family-Cancer Project Database, we identified 9,522 individuals with primary HL diagnosed bet

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OBJECTIVES: Degenerative mitral valve disease is the most common indication for mitral valve repair in the Western world. The aim of this study was to study the long term outcome of mitral valve repair for degenerative mitral valve regurgitation in Iceland. MATERIAL AND METHODS: A retrospective study of 101 consecutive mitral valve repair patients (average age 57.7 years, 80.2% male) operated in I

Myocardial infarction in diffuse large B-cell lymphoma patients – a population-based matched cohort study

Background: The outcome for diffuse large B-cell lymphoma (DLBCL) patients has improved with the immunochemotherapy combination R-CHOP. An increased rate of heart failure is well documented following this treatment, whereas incidence and outcome of other cardiac complications, for example myocardial infarction, are less well known. Method: We identified 3548 curatively treated DLBCL patients in Sw

Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women

Thyroid cancer (TC) is substantially more common in women than in men, pointing to a possible role of sex steroid hormones. We investigated the association between circulating sex steroid hormones, sex hormone binding globulin (SHBG) and the risk of differentiated TC in men and women within the European Prospective Investigation into Cancer and nutrition (EPIC) cohort. During follow-up, we identif

Ignition, stabilization and particle-particle collision in lifted aluminum particle cloud flames

Micron-sized aluminum (Al) particles have recently been proposed as promising carbon-free energy carriers. To facilitate the application of micron-sized Al particles as fuel in practical energy generation system, this study experimentally investigates the underlying mechanisms of the ignition, stabilization and particle-particle collision in lifted Al particle cloud flames. High-resolution shadowg

The Vitamin D Receptor as a Prognostic Marker in Breast Cancer-A Cohort Study

Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S

Experimental Investigation of Pilot Injection Strategies to Aid Low Load Compression Ignition of Neat Methanol

The growing demand to lower greenhouse gas emissions and transition from fossil fuels, has put methanol in the spotlight. Methanol can be produced from renewable sources and has the property of burning almost soot-free in compression ignition (CI) engines. Consequently, there has been a notable increase in research and development activities directed towards exploring methanol as a viable substitu

An experimental and modeling study on the laminar burning velocities of ammonia + oxygen + argon mixtures

Most often, the laminar burning velocity (SL) of ammonia was measured in mixtures diluted by nitrogen bearing in mind its potential use as an alternative carbon-free fuel. Replacing the diluent with argon can increase the flame temperature and thus provide additional targets for validating pertinent detailed kinetic models. The SL data for ammonia + oxygen + argon mixtures are scarce; therefore, i

Hållbar Upphandling; En studie om upphandling occh vad som krävs för att klara en certifiering enligt ISO-20400

Bygg- och fastighetssektorn är en av de sektorer som släpper ut mest växthusgaser. Under ett enskilt år så svarar byggbranschen för utsläpp av växthusgaser på 21 miljoner ton koldioxidekvivalenter, vilket motsvarar 21 procent av Sveriges totala utsläpp. Av det totala utsläppet på 21 miljoner koldioxidekvivalenter så kommer 12,8 miljoner ton från inhemska utsläpp av växthusgaser och 8,2 miljoner toThe building and real estate sector is one of the sectors that emits the most greenhouse gases. For a single year, the construction industry is responsible for greenhouse gas emissions of 21 million tons of carbon dioxide equivalent, which corresponds to 21 per cent of Sweden's total emissions. Of the total emissions of 21 million carbon dioxide equivalents, 12.8 million tons come from domesti

Extraction of Cellulose and Nanocellulose from the Green Seaweed Ulva sp.1 for Characterisation and Investigation of Processing Effects

Development of valuable products from downstream process residual biomasses and profound reduction of waste are two key components for developing a more sustainable process industry. The importance of bio-renewable feedstocks and bio-based processing techniques are also crucial in the transformation to a more sustainable and green society. Therefore focus is directed on full exploitation of seawee

"Människor i kris kan ju inte jobba med förändring" : En kvalitativ studie om hur socialsekreterare resonerar kring föräldrars rätt till stöd när deras barn omhändertagits enligt LVU

Authors: Emma Nilsson and Emma Silverberg Title: People in a crisis are not able to work with change Supervisor: Helene Hansen Assessor: Mikael Sandgren The aim of this study was to examine social workers reasoning on social services support to parents of children placed in compulsory care. This study was based on the Swedish social services law, 6:7 Socialtjänstlagen, that describes that parents

Analys & effektivisering av ABB Swedewaters materialhanteringsprocess

Bakgrund: Generellt bland industrivärldens lager är denhuvudsakliga uppgiften försörjning av material mot montering och tillverkning. Så är fallet även på ABB Swedewater. När en produkt ska tillverkas plockar personalen på lagret ihop de komponenter som behövs och skickar dem till tillverkningen. Materialet till anläggningen ”kittas” för att underlätta arbetet i produktion. Detta betonar vikten avBackground: Generally among industrialized warehouses, the main operational task is to supply the assembly or manufacturing with material, so is also the situation at ABB Swedewater. When manufacturing a product, the warehouse personnel pick necessary components requested by othersections of the production. This stresses the importance of a correct performance when picking, as this forms the base

Förändrad gradindelning och straffvärdebedömning för narkotikabrott - revolution eller tillnyktring?

Narkotika har sedan 1960-talet utgjort ett allvarligt samhällsproblem i Sverige. En skyndsam utbredning har varit en bidragande faktor till stor del av den grova brottsligheten i landet. På 1970-talet infördes målet om ett narkotikafritt samhälle i Norden, vilket sedan dess varit ledande för Sverige. Utmärkande för Sveriges narkotikapolitik är ett strängt och restriktivt förhållningssätt. Ett narkDrugs were noted as a serious public issue in Sweden during the 1960s with its accelerated expansion and conduciveness to heavy criminality. During the 1970s, the drug policy towards a drug free society was introduced in the Nordic region, and is still today advocated in Sweden. The drug policy in Sweden is known for the severe and restrictive approach. The drug policy has characterized the Swedis