Sökresultat

PowerPoint Presentation E-learning Module 1 Scanning at 7T Introduction This module introduces main elements that differentiates scanning at 7T from scanning at 3T, from a users perspective. Aspects of 7T physics are described, and examples of how that impact scanning will be given, with a focus on the additional challenges of scanning at 7T. In the end is a small quiz that can be used for testing

https://www.lbic.lu.se/sites/lbic.lu.se/files/philips_e-learning_7t.ppsx - 2026-07-17

Background: More than ever, clinicians need regularly updated reviews given the continuously increasing amount of new information regarding innovative cervical cancer prevention methods. Material and methods: A summary is given from recently published meta-analyses on three possible clinical applications of human papillomavirus (HPV)-DNA testing: triage of women with equivocal or low-grade cytolog

This thesis concerns the application of artificial neural network techniques to space weather physics. The networks applied include multi-layer error-backpropagation, radial basis function, and self-organized maps. Different parts in the solar-terrestrial chain are analysed with the emphasis on developing methods for real time predictions of geomagnetic activity. The neural networks are general mo

Seven-transmembrane G-protein-coupled receptors play a central role in physiology by facilitating cell communication through recognition of a wide range of ligands. Even more important, they represent important drug targets. Unfortunately, for many of these receptors the endogenous ligands, and hence their functions, remain to be identified. These receptors are referred to as "orphan" receptors. A

In recent years, nanostructure technology involving Ill-V semiconductors have made significant progress in areas such as optoelectronics and spintronics. A number of new materials and nanostructures have been invented, most of them being of a very dilute character or extremely small. Because of these properties, their structural characterization on an atomic scale is of profound importance. One im

This thesis discusses modeling and implementation of reconfigurable hardware architectures for real-time applications. The target application in this work is digital holographic imaging, where visible images are to be reconstructed based on holographic recordings. The reconstruction process is computationally demanding and requires hardware acceleration to achieve real-time performance. Thus, this

Nanowires were grown by means of a novel aerosol-based method called Aerotaxy. Here an aerosol of Au catalyst nanoparticles in N-2 is mixed with MOVPE precursors in a flow-through reactor at atmospheric pressure, whereby nanowires are produced continuously in high concentrations. We demonstrate the possibility of in situ doping of the NWs and the realization of well-controlled p-type GaAs nanowire

Studies aimed at the identification of biomarkers and treatment targets of cancer have focused on mRNAs, miRNAs, and proteins expressed by malignant cells, while glycoproteins mainly produced by stromal cells remain relatively unexplored. Glycans lack a given template for their biosynthesis that involves the concerted action of several, sometimes >15 different enzymes. This fact complicates the an

We report the solution structure of human prolactin determined by NMR spectroscopy. Our result is a significant improvement over a previous structure in terms of number and distribution of distance restraints, regularity of secondary structure, and potential energy. More significantly, the structure is sufficiently different that it leads to different conclusions regarding the mechanism of recepto

Intracellular lipolysis is a major pathway of lipid metabolism that has roles, not only in the provision of free fatty acids as energy substrate, but also in intracellular signal transduction. The latter is likely to be particularly important in the regulation of insulin secretion from islet beta-cells. The mechanisms by which lipolysis is regulated in different tissues is, therefore, of considera

Background. To evaluate the relationship between age and poor ovarian response to pregnancy and cancellation rate after IVF stimulation. Methods. Poor ovarian response was defined as <= 5 follicles at ovum pick up (OPU). Out of 1,706 consecutive OPUs performed during 2003/2004, 290 poor responders were identified. This cohort of poor responders was divided into two groups, 'older' and 'younger', w

The calcineurin/nuclear factor of activated T cells ( NFAT) signaling pathway has been found to play a role in regulating growth and differentiation in several cell types. However, the functional significance of NFAT in the vasculature is largely unclear. Here we show that NFATc1, NFATc3, and NFATc4 are expressed in human myometrial arteries. Confocal immunofluorescence and Western blot analysis r

POU5F1 has two alternatively spliced transcripts: a long (variant 1, NM_002701) and a short (variant 2, NM_203289) transcript. Only variant 1 is a key regulator of pluripotency. Hence, it is important to be able to distinguish this transcript from variant 2 and from the many pseudogenes present in the genome. Previous studies on the expression of POU5F1 were, however, usually carried out without c

Gaia, the next astrometric mission of the European Space Agency, will use a camera composed of 106 CCDs to collect multiple observations for one billion stars. The astrometric core solution of Gaia will use the estimated location of the stellar images on the CCDs to derive the astrometric parameters (position, parallax and proper motion) of the stars. The Gaia CCDs will suffer from charge transfer

Abstract in UndeterminedA common finding of 30–40 years of family migration studies worldwide is that such migration primarily benefits the careers of men in couples but generally damages the women’s careers. Findings have recently become more nuanced as the research focus has broadened,hinting that families returning to one spouse’s region of previous residence might deviate from this general obs

The emergence of automated image analysis algorithms has aided the enumeration, quantification, and immunohistochemical analyses of tumor cells in both whole section and tissue microarray samples. To date, the focus of such algorithms in the breast cancer setting has been on traditional markers in the common invasive ductal carcinoma subtype. Here, we aimed to optimize and validate an automated an

Metastatic disease is responsible for most cancer deaths, and hematogenous spread through circulating tumor cells (CTC) is a prerequisite for tumor dissemination. CTCs may undergo epithelial–mesenchymal transition where many epithelial cell characteristics are lost. Therefore, CTC isolation systems relying on epithelial cell markers are at risk of losing important subpopulations of cells. Here, a

The article focuses on individual students’ studies within a practicebased MFA program in visual art in Sweden. The individual cases of studying that form the basis for this investigation, represent a particularly autonomous and self-directed kind of studying. Although the kind of autonomy and selfdirection varies between visual art programs, as well as its extent, these are largely qualities that

Nitric oxide (NO) is a multifunctional signalling molecule, acting as a vasodilator, neurotransmitter, and modulator of inflammatory processes. It also participates in killing parasites, virus-infected cells, and tumor cells by formation of peroxynitrite, one of the most important initiators of the free radical damage. Uncontrolled production of NO can lead to nitrosative stress, causing damages t

Copper are generally bound to proteins, e.g. the prion and the amyloid beta proteins. We have previously shown that copper ions are required to nitrosylate thiol groups in the core protein of glypican-1, a heparan sulfate-substituted proteoglycan. When S-nitrosylated glypican-1 is then exposed to an appropriate reducing agent, such as ascorbate, nitric oxide is released and autocatalyzes deaminati