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Identifying the genetic variants that regulate fasting glucose concentrations may further our understanding of the pathogenesis of diabetes. We therefore investigated the association of fasting glucose levels with SNPs in 2 genome-wide scans including a total of 5,088 nondiabetic individuals from Finland and Sardinia. We found a significant association between the SNP rs563694 and fasting glucose
Context. The Milky Way nuclear star cluster (MWNSC) is located in the Galactic centre, together with the Milky Way nuclear stellar disc (MWNSD), and they dominate the gravitational potential within the inner 300 pc. However, the formation and evolution of the two systems and their possible connections are still under debate. Aims. We reanalysed the low-resolution KMOS spectra in the MWNSC with the
2593Background: PD-1 blockade has demonstrated positive anti-tumor activity across multiple tumor types. While the anti-tumoral response can be substantial and even curative, response rates remain low in many cancer types. Long-lasting responses are only observed in a minority of patients, and additional immunotherapeutic alternatives remain limited for patients who fail to respond or initially re
In very recent years, growing efforts have been devoted to the development of all-polymer solar cells (all-PSCs). One of the advantages of all-PSCs over the fullerene-based PSCs is the versatile design of both donor and acceptor polymers which allows the optimization of energy levels to maximize the open-circuit voltage (Voc). However, there is no successful example of all-PSCs with both high Voc
Background and AimsOlder persons with problematic alcohol use vary in psychosocial functioning, age of onset for problem drinking and use of other drugs. The study measured the differential risks of all-cause, alcohol, polydrug and psychiatric-related repeated hospitalizations among older persons with problematic alcohol use.DesignA linked register-based cohort study with discontinuous multiple-fa
Popular Abstract in Swedish Vår forskningsgrupp har tidigare påvisat kraftiga förändringar i genuttryck för neurotrofiner, en familj av tillväxtfaktorer för nervceller, och deras receptorer i kortikala och hippokampala nervceller vid olika hjärnskador. Det är till stora delar okänt vilken funktion neurotrofiner har efter hjärnskador, men neurotrofinsvaret skulle kunna vara en skyddande mekanism ocThis study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i.e., hippocampus and striatum, by combining specifi
Titel: Vem va’ det som kasta’? – en fallstudie av den svenska nyhetsrapporteringen i samband med fotbollsrelaterat läktarvåld Författare: Jimmy Modin och Arvid Nikka. Enhet: Medie- och kommunikationsvetenskap. Institutionen för kommunikation och medier, Lunds Universitet. Sammanfattning: Grunden för uppsatsen ligger i en nyligen genomförd undersökning av analysföretaget Novus. Undersökningen vi
The aim of this article is to draw attention to the dangerous, indeed poisonous, nature of the current debates on immigration and multiculturalism in today’s ‘omniphobic’ Europe, plagued not only by a severe economic crisis, but also a more general normative crisis, a ‘crisis of values’ so to speak, which has been consistently overlooked or manipulated by politicians and academics alike, or reduce
On July 2018, for the first time in modern Mexican history, a leftist candidate won the presidential elections in Mexico. With large promises on the eradication of corruption and ending social injustice, Andrés Manuel López Obrador and his party secured both the presidency and both chambers of the Mexican Congress. This paper inquires into to what extent a president belonging to the political left
The emergence of blockchain technology enables entrepreneurs to raise capital in an innovative way, by addressing a crowd of online investors without the need for an intermediary. This phenomenon is known as token sales, and it may have the potential to revolutionize entrepreneurial finance. However, information asymmetry is particularly severe in this context, and the need for entrepreneurs to se
Medieval Europe was characterized by geopolitical disorder and territorial disunion. Around 1500 AD, as the modern era dawned, Europe comprised some 1,500 districts which were largely politically independent. Gradually, medium sized territories emerged around cores made up of cultural, economic, and political centres. The Lake Malar area in Sweden was such a territory; London, Paris, Berlin-Potsda
A growing body of research highlights how the Internet and social media offer new platforms for advocacy. This article contributes to the debates on digital advocacy by combining interest group and social media studies and present the notions of digital access politics, digital information politics, and digital protest politics for a comprehensive analysis of digital advocacy. Based on a netnograp
Drawing upon the perspective of the cultural studies of emotions, this article examines the reception of political satire and the re-contextualization of humour. More precisely, it investigates the multiplicity of tensions that come into play in the production, erasure, rediscovery, and reception in BelarusianInternet media of politically oriented Russian television humour mocking the Belarusian p
In ESS, a 5 MW proton beam will hit a helium cooled tungsten target to generate neutrons by spallation. For the purpose of investigating various aspects of cooling with helium, an experimental system has been constructed at Lund University, Department of Energy Sciences. A helium flow of 3 g/s is circulated in a closed loop with pre-heater, cooler, filters and a test vessel. The vessel has windows
